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Results Ultrasound studies have demonstrated that 14 cases chromosomal defects are associated with multiple fetal abnormalities, including 11 cases cardiac abnormalities (78.6%), 9 cases hydroamniofluids (64.3%), 8 cases mild ventriculomegaly (57.1%), 7 cases fetal growth restriction (50%), 5 cases abnormal umbilical arterial doppler waveforms (35.7%), 4 cases esophageal atresia (28.6%), 3 cases exomphalos (21.4%), 1 cases clubhands (7.1%), 1 cases cleft lip (7.1%).

结果 14例胎儿产前超声检查均发现二项以上的超声表现异常,其中心脏结构异常11例(78.6%);羊水过多9例(64.3%);脑室增宽8例(57.1%);胎儿生长受限7例(50%);脐动脉血流指标增高5例(35.7%);食道闭锁4例(28.6%);脐疝3例(21.4%);腕关节异常1例(7.1%);唇裂1例(7.1%)。

Lthough a low frequency of abnormal growthof nucellus was observed,no embryo originating from nucellus cell and integumentwas found.

PⅣ珠心组织出现低频率的异常生长现象,但未观察到由珠心细胞发育形成的不定胚。

The research advance on organogenesis, somatic embryogenesis and protoplast regeneration system of soybean are introduced in this paper.

终于在20世纪80年代初期有了转机,人们选择了幼胚、幼胚子叶或胚轴为外植体,用异常高浓度的植物生长调节物质,建立了大豆的体细胞胚胎发生和器官发生再生系统。

Agents of the Company's products urapidil grass for functional health supplies, urapidil grass under the Cyperaceae, the natural growth of herbaceous plants for many years, leaves soft, fibrous dysplasia tenacity.

本公司代理的乌拉草系列产品为功能性保健用品,乌拉草隶属莎草科,自然生长的多年草本植物,叶片柔软,纤维异常坚韧。

Observation under Transmission Electron Microscope was carried out and growth curve of E. coli was ploted out. It was indicated that PSPPs might change the permeability of cell membrane, make cell excrescent and inhibit cell division.

透射电镜观察和大肠杆菌生长曲线表明,该色素的抑菌作用可能是通过增强细胞膜的通透性,使细胞异常生长,抑制对数生长期的细胞分裂,使细胞质稀薄、细胞解体。

The main changes were the downward and backward rotation of the mandible, the retrusion of the lower incisors, the protrusion of the upper incisors.FR-Ⅲ also promotes the growth of maxilla and reaches the normal relationship of the anterior overjet and overbite.

结果:FR-Ⅲ能矫正上下颌基骨异常的矢状关系,主要变化是下颌骨向下、向后旋转,改变下颌骨生长的方向,同时使下颌切牙舌倾、上前牙唇倾,上颌骨向前生长。

Though the primary stimulator of 1H is not clear, it is related to physical, cell and body fluid IH is a chronic process involving multiple faction injury and blood flowing abnormal are revamped as the main reason, the proliferation level depend on the length and width of the injure of vessel large amount research illustrate injury cause many growth factor infolded in IH, for example: template derived growth factor, fibroblast growth factor, transmission growth factor , endothelin (ET-1) et al, some early responsive gene such as c-fos、c-jun c-myc also take part in SMC proliferation after vessel injury.

虽然IH的确切起始刺激因子并未阐明,但已知与物理、细胞和体液因子有关。IH是一个多因素参与的慢性过程,损伤和血液动力学异常一真被认为是IH的主要因素。内膜增殖的程度有赖于血管损伤的长度和深度。近年来大量的实验研究结果表明,损伤等刺激引起的众多的生长因子样物质在IH中起关键作用。如血小板源性生长因子、碱性纤维母细胞生长因子、转化生长因子β、内皮素-1(ET-1)等诸如C-fos、C-jun、C-myc等早期应答基因也参与了血管损伤后SMC的增殖。

During the first two weeks after birth, the growth performances were not significant between the mutant mice and the normal ones, but after that, the mutant mice grew much slower. The differences were significant in the indexes of eyes, lungs, thymuses, and adrenal glands between the genders. At the same time, the differences were significant in the organ indexes, such as lungs, adrenal glands, uterine and testicles between the normal phenotype mutant mice and the abnormal ones. And these two kinds of mice showed different amount of hemoglobin and red blood cell.

结果:B6-Co小鼠不育率22%、平均产仔数5.62±2.55只、离乳成活率56.59±41.22显著低于正常的B6小鼠,而胎间隔29.50±10.50天比正常B6小鼠短。B6-Co小鼠出生后2周内生长发育与正常B6小鼠基本一致,2周后,其生长发育慢于正常B6小鼠。B6-Co小鼠雌雄间的眼球、肺、胸腺、肾上腺的脏器指数差异有统计学意义。B6-Co表型异常小鼠与B6-Co表型正常小鼠相比,肺、肾上腺、子宫、睾丸的脏器系数差异有统计学意义。B6-Co小鼠表型异常小鼠在血红蛋白和红细胞数量上异于B6-Co表型正常小鼠。

Results: B6-Co mice showed higher sterile rate, and significant lower average litter size and survival rate at weaning than the normal B6 mice, but the time interval between deliveries was shorter in the mutant population. During the first two weeks after birth, the growth performances were not significant between the mutant mice and the normal ones, but after that, the mutant mice grew much slower. The differences were significant in the indexes of eyes, lungs, thymuses, and adrenal glands between the genders. At the same time, the differences were significant in the organ indexes, such as lungs, adrenal glands, uterine and testicles between the normal phenotype mutant mice and the abnormal ones. And these two kinds of mice showed different amount of hemoglobin and red blood cell.

结果:B6-Co小鼠不育率22%、平均产仔数5.62±2.55只、离乳成活率56.59±41.22显著低于正常的B6小鼠,而胎间隔29.50±10.50天比正常B6小鼠短。B6-Co小鼠出生后2周内生长发育与正常B6小鼠基本一致,2周后,其生长发育慢于正常B6小鼠。B6-Co小鼠雌雄间的眼球、肺、胸腺、肾上腺的脏器指数差异有统计学意义。B6-Co表型异常小鼠与B6-Co表型正常小鼠相比,肺、肾上腺、子宫、睾丸的脏器系数差异有统计学意义。B6-Co小鼠表型异常小鼠在血红蛋白和红细胞数量上异于B6-Co表型正常小鼠。

Theoretically, re-expression of tumor suppressor genes by demethylating agents may contribute to inhibiting the development of tumor. It has been suggested that DNA hypermethylation results in resistance to chemotherapy and consequently reduces the efficacy of chemotherapeutic treatment.

由于高度甲基化而暂停表达的抑癌基因,如果能应用去甲基化制剂逆转甲基化的异常状态,使之重获表达,理论上即可发挥其抑制肿瘤细胞生长的功能。

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