异常发育

In view of geological records preserved from different regions of the world are not identical, it's suggested that, when correlating the Ordovician-Silurian boundary, at the global boundary stratotype section, the FAD of N. persculptus be selected as the biomark, the transgression event identical to the FAD of N. persculptus as the auxiliary physical mark and the mass extinction and chemical anomaly events respectively as the auxiliary biomark and chemomark. In some regions with few graptolite, the Ordovician-Silurian boundary should be indicated by the auxiliary marks, such as the transgression event, mass extinction or chemical anomaly event, with the other fossil such as conodont nearest to other geological events as the provincial biomark for correlation. In other regions with much stratigraphic hiatus originated from the regression, the Ordovician-Silurian boundary should be marked by the regression-transgression event nearly relevant to the N. persculptus Zone.

鉴于不同地区留下的地质记录不完全相同，奥陶/志留系界线对比方法不同：在界线层型剖面上，以N.persculptus的首现为生物标志，以与之基本一致的海侵事件为辅助的物理标志，以生物集群绝灭事件和化学异常事件为辅助的生物和化学标志；在笔石极不发育的地区，则以海侵事件、生物绝灭事件或化学异常事件为辅助标志，以与其相距最近、并且具有区域对比性的其它门类化石作为界线对比的生物标志；对于由于海退事件所造成地层缺失很多的地区，则以海退/海侵事件作为划分界线的物理标志，并以相映的海侵事件的开始作为奥陶/志留系的分界。

In viewof geological records preserved from different regions of the world are not identical, its suggested that, whencorrelating the Ordovician-Silurian boundary, at the global boundary stratotype section, the FAD of N.persculptus be selected as the biomark, the transgression event identical to the FAD of N. persculptus as theauxiliary physical mark and the mass extinction and chemical anomaly events respectively as the auxiliarybiomark and chemomark. In some regions with few graptolite, the Ordovician-Silurian boundary should beindicated by the auxiliary marks, such as the transgression event, mass extinction or chemical anomaly event,with the other fossil such as conodont nearest to other geological events as the provincial biomark forcorrelation. In other regions with much stratigraphic hiatus originated from the regression, theOrdovician-Silurian boundary should he marked by the regression-transgression event nearly relevant to the N.persculptus Zone.

鉴于不同地区留下的地质记录不完全相同，奥陶／志留系界线对比方法不同：在界线层型剖面上，以N.persculptus的首现为生物标志，以与之基本一致的海侵事件为辅助的物理标志，以生物集群绝灭事件和化学异常事件为辅助的生物和化学标志；在笔石极不发育的地区，则以海侵事件、生物绝灭事件或化学异常事件为辅助标志，以与其相距最近、并且具有区域对比性的其它门类化石作为界线对比的生物标志；对于由于海退事件所造成地层缺失很多的地区，则以海退／海侵事件作为划分界线的物理标志，并以相映的海侵事件的开始作为奥陶／志留系的分界。

Cases of the abnormal sex differentiated diseases in children were presented. Among them, there were 4 cases of Turner's syndrome, 1 Klinefelter's syndrome, 9 female pseudohermaphroditism, 2 male pseudohermaphroditism, and 4 true hermaphroditism.

本文报道小儿性分化异常疾病20例(包括先天性卵巢发育不全综合征4例、先天性睾丸发育不全综合征1例、女性假两性畸型9例、男性假两性畸型2例、真两性畸型4例)，对上述病例进行了细胞染色体核型分析，同时作了口腔上皮细胞性染色质、中性粒细胞核鼓植体及尿17酮类固醇、17羟类固醇的检查。

Pre-school children's eyes in the growth and development has a certain degree of physiological hyperopia, eye development is the normal course of its normal value for :3-4-year-old hyperopia within 200 degrees, 4-5-year-old hypermetropia less than 150 degrees, 6-8-year-old hypermetropia less than 100, more than the normal range, and compared with the abnormal or pathological hyperopia.

学龄前儿童的眼睛在生长发育中有一定的生理远视，是眼发育的正常过程，它的正常值为：3-4岁远视200度以内，4-5岁远视150度以内，6-8岁远视100以内，超过正常范围的，则为异常的或病理性远视。

So,detection of SRY gene may play an important role in the study of hypospadias.

2先天性尿道下裂是一种性别发育异常，尿道缺失是性腺发育不全表现。

All cases tested were immunoreactive for S100 and CD34; Mib-1 reactivity was absent to low. Cytogenetic aberrations included chromosome 8 abnormalities in 8 cases, nonspecific numerical abnormalities in 1 case, and a normal karyotype in 1 case. Ten patients had other medical conditions including macrocephaly, seizures, developmental delay, autism, congenital anomalies, Sturge-Weber syndrome, or a family history of multiple lipomas.

免疫组化所标病例均表达S100和CD34 ；Mib-1指数为零或低。8例细胞遗传学显示8号染色体异常，1例显示非特异性染色体数目异常，1例显示正常染色体组型。10例患者伴有其他疾病：巨头畸形、癫痫、发育延迟、自闭症、先天畸形、斯德奇-韦伯综合症、多发性脂肪瘤家族史。

There is a cognitive disorder in 85.7 percent of microcephaly children with atelencephalia that is influenced by multifarious factors.

结果 42例患儿发育商值异常者占85.7%（36/42），影响早期认知功能的因素主要包括患儿有异常头颅影像学改变、性别、初诊年龄。

Calidonian granites are widely developed in the Yema Nanshan area in the western segment of the Qilian orogenic belt. The geochemical characteristics of most of the granites are similar to those of adakites: SiO2≥56%, Al2O3≥15.0%, low MgO (average 2.04%), high Sr (257-889μg/g, average 546.42μg/g), low Y (7.1-25.3μg/g,average 16.67μg/g), average Sr/Y=5.89, no pronounced Eu anomaly and Sr positive anomaly. Adakites in this area have five rock types, quartz diorite, quartz monzodiorite, quartz monzonite, monzogrannite and hornblende granite. These rocks commonly contain hornblende, belonging to I-type granites.

提要：祁连西段野马南山一带发育大量的加里东期花岗岩，其中大部分花岗岩具有与adakite岩相似的地球化学特征，SiO2≥56%， Al2O3≥15.0％，低MgO（平均2.04％），高Sr(257～889μg/g，平均值546.42μg/g)，低Y（7.1～25.3μg/g，平均16.67μg/g），Sr/Y平均为35.89μg/g，Eu无明显负异常，Sr正异常，Adakite岩石类型有石英闪长岩、石英二长闪长岩、石英二长岩、角闪花岗岩、二长花岗岩，岩石中普遍含有角闪石，属I型花岗岩，地球化学图解反映该花岗岩形成环境为板块碰撞前的岛弧型，锆石U-Pb同位素年龄为444+38/-33 Ma，处在祁连造山带板块俯冲收缩阶段，因此可以推断野马南山埃达克质Adakite花岗岩是俯冲板片部分融熔和壳幔岩浆混合形成的。

For example, in McCune-Albright syndrome, there are patchy dysplastic changes in the bone, abnormalities of endocrine glands, patchy pigmentary changes, and occasionally abnormalities in the heart or liver.

例如在McCune-Albright综合征中，骨中有发育不良斑块，还有内分泌腺异常，色素斑以及偶有心或肝的异常。

For example, in McCune-Albright syndrome, there are patchy dy lastic changes in the bone, a ormalities of endocrine glands, patchy pigmentary changes, and occasionally a ormalities in the heart or liver.

例如在McCune-Albright综合征中，骨中有发育不良斑块，还有内分泌腺异常，色素斑以及偶有心或肝的异常。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。