异常发育

Holoprosencephaly is the most common abnormality of the deelopment of the forebrain in humans.

前脑无裂畸形是人类前脑发育异常中最常见的类型。

In addition, germ-line epimutations of other tumor suppressor genes, such as MSH2 and BRCA1, have also been reported, demonstrating that epimutations might arise in the germ-line (during gametogenesis or early embryonic development).

随后，关于其他抑癌基因MSH2与BRCA1等的胚系异常甲基化也陆续有报道。这提示，表观突变也可以起源于胚系（生殖细胞形成期或胚胎发育早期），从而造成全身细胞广泛的基因转录沉默。

One patient had transient insufficient blood supply of the glans and recovered gradually by symptomatic treatment.

结果：26例患者都有不同程度的阴茎浅筋膜发育异常，22例患者行阴茎海绵体松解牵拉术，10例行maizels术。

Zhuyangguan -Xiaguan fault zone is a long 40 km translithospheric fracture, on the way fracture appear in public many Yanshanian cycle granite -porphyry and some Cu、Au、Ag、Pb、Zn anomaly and the noplemetal metalliztion developed.

朱阳关-夏馆断裂是一条长约400余km、深达上地幔的超壳断裂，沿断裂出露有较多的燕山期花岗斑岩小岩体及一系列Cu，Au，Ag，Pb，Zn异常，有色金属、贵金属成矿作用发育。

The results showed that high incubation temperature caused early hatched chickens, and low hatchability and abnormal newly hatched chickens increased.

试验结果显示，高温会加速胚胎发育且提早孵出时间，并导致孵化率下降以及雏鸡异常数增加。

Results All the patients of this group had characteristics of ineffective hematopoiesis.

结果：所有患者均存在不同程度的血细胞发育异常的形态学表现。

Intracal malacoma 32 cases,cyst of pellucid septal cave 19 cases ,alba dysplasia 16 cases,grey matter heterotopia 7cases,porencephaly...

脑瘫的CT检查有极高的价值：胚胎期发育异常和新生儿窒息可能是该地区小儿脑瘫的主要病因。

Neurodevelopmental disability is proportionate to the thickness of the heterotopic "band." The manifestations of this x-linked disease are more drastic than SEH; males suffer from lissencephaly, while females suffer from band heterotopia.

神经发育异常的严重程度取决于灰质带的厚度。。X-连锁性病变的现象比SEH更明显，男性表现为无脑回，女性表现为带状异位。

Their ages ranged 6 to 13 years. Their EEGs were characterized by continuous spike-and-wave discharges during non-rapid eye movement sleep, accounting for 85%-100% of the period of NREM sleep. Clinically, these children had various types of epileptic seizures and exhibited different degrees of neuropsychiatric impairments, language dysfunction, and/or behavioral disturbances. Neuroimaging abnormalities were found in 6 cases, including atelencephalia or atrophy, gray matter heterotopia and leucomalacia. CONCLUSIONS: This study indicates the characteristics of CSWS syndrome in clinical manifestations, EEG and neuroimaging examinations.

结果：9例患儿的视频脑电图结果符合CSWS诊断标准，年龄6~13岁，脑电图表现为棘慢复合波在整个非快速眼动睡眠期几乎持续存在，其放电时间占整个NREM期的85%~100%；临床上患者表现不同类型的癫癎发作，在神经精神方面存在不同程度的损害，存在言语和/或行为障碍；其中6例患儿显示有神经影像学异常，包括脑发育不全或萎缩、灰质异位、脑白质软化等。

On the variations of cerebral arteries of 204 cases on MR angiograms, the hypogenesis and absence of ACA A1 segment were seen in 10.8% and 8.3% separately, branching earlier of MCA in 1.5%, PCoA in 61.3%, fetaltype PCA in 29.9%, and the abnormal communicating arteries between ICA and BA system in 0.5%.

三、脑动脉的MRA变异中，ACA-A1段发育不良率10.8％，缺如率8.3％；MCA过早分支率1.5％；PCoA的显示率61.3％，FTP发生率29.9％；ICA与BA系统的异常交通发生率0.5％。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。