异常

In the long-period toxicity test, DCG was administered repeatedly for 60 days, the dose were 72.6,36.3,18.2 g/kg respectively(It refered to the dose of material,which amounted to 52.6,26.3,13.2 times of 50 kg human clinic use). There is no other abnormal changes about color patem,action,urine and stool,but cibation, hydroposia, body weight and index part of hematological and hematobiochemical parameters,coefficient and histomorphological figure of organs were examined during administration phase.The rats were examined in 21 days after the cessation of DCG, the abnormal changes of index was completely recovered.

定喘颗粒大鼠给药60 d的毒性试验，剂量分别为72.6，36.3，18.2 g/kg（相当于临床50 kg人用量的52.6，26.3和13.2倍），给药期间各组大鼠毛色、活动、二便均无异常变化，但给药组大鼠摄食、饮水、体重以及部分血液学、血液生化学指标和脏器系数有异常变化，停药后，上述异常变化指标均已恢复正常。

Results For the first primary lesions,most of them were stage IIa, including 12 invasive ductal caicinoma, 5DCIS, 2 invasive lobular caicinoma, a invasive carcinoma with cribriform pattern and 1 case mixed-cell carcinoma. On FFDM, 5 had microcalcification,13 were mass, 1 showed focal high attenuation and 2 were not detected. For the second primary lesions, most of them were stage 0, including 7 invasive ductal carcinoma, 12 DCIS ,1 invasive lobular carcinoma, 1 mixed-cell carcinoma.

结果；第一原发癌以Ⅱa期为主，浸润性导管癌12例，导管原位癌5例，浸润性小叶癌2例，浸润性筛状癌1例，混合细胞癌1例；5例以微钙化为主要表现，13例肿块，局部密度曾浓1例，2例未见异常；第二原发性癌以0期为主，浸润性异常癌7例，导管原位癌12例，浸润性小叶癌1例，混合细胞癌1例；11例以微钙化为主要表现，肿块3例，结构不良4例，局部密度曾浓1例，2例未见异常。

Methods Totally 173 patients diagnosed as MDS according to FAB or WHO criteria with complete clinical and cytogenetical data were included in this reseach.

方法应用骨髓细胞短期培养法和染色体G显带技术，部分病例联合应用荧光原位杂交技术，对42例细胞遗传学检查具有+8异常克隆，16例具有-7/7q-异常克隆，以及55例虽然经常规细胞遗传学检查未检出异常克隆，但是骨髓涂片原始细胞≥0.10，按照FAB或WHO标准既往诊断为MDS的病例进行了临床及血液形态学和细胞遗传学的系列研究。

Methods Totally 173 patients diagnosed as MDS according to FAB or WHO criteria with complete clinical and cytogenetical data were included in this reseach. Among them 42 had +8 chromosome aberration, 16 had -7/7q-, and 55 had normal karyotypes and more than 0.10 blast cells in the bone marrow. Short term culture and G-banding techniques and in some specimens fluorescence in situ hybridization method were used to do chromosome analysis.

方法应用骨髓细胞短期培养法和染色体G显带技术，部分病例联合应用荧光原位杂交技术，对42例细胞遗传学检查具有+8异常克隆，16例具有-7/7q-异常克隆，以及55例虽然经常规细胞遗传学检查未检出异常克隆，但是骨髓涂片原始细胞≥0.10，按照FAB或WHO标准既往诊断为MDS的病例进行了临床及血液形态学和细胞遗传学的系列研究。

Subacut myeloid leukemia can be a defined type of leukemia. The common characteristics of subacute myeloid leukemia are as follows: the onset is insidious, and anemia and hemorrhage of skin and mucosa are the main clinical manifestations. Hepatosplenomegaly is rare. There are multilineage abnormalities in blood cell counts and increased blasts in the bone marrow with cytogenetical abnormal clone in most cases. The disease course is subacute and progressive.

1、亚急性髓性白血病是一个可以确定的白血病类型，其特征为：起病隐袭，以贫血或皮肤粘膜出血为主要症状，肝脾肿大的特征较少，血象为一系、二系或三系的异常，骨髓细胞形态学检查原早幼粒细胞异常增高，细胞遗传学检查多数有克隆性异常核型，病程中可有克隆演进，呈现亚急性而进行性的临床经过。

Results: CK18 was not detected in normal and abnormal oral tissue sections. But in normal nonkeratinized mucosa, CK19 was detected in the basal cell layer dispersively. In epithelial dysplasia, CK19 was detected in the suprabasal cell layer and the number of CK19-positive cell layers was correlated with the dysplasia degree of epithelia. Furthermore, CK19 was detected in oral squamous cell carcinoma, especially in the poor-differentiated cancer cells.

结果：正常和异常的口腔粘膜均未检测到CK18；CK19可表达于正常非角化上皮的基底层细胞、异常增生上皮的基底上层细胞及口腔鳞状细胞癌中，阳性细胞数与上皮的异常增生程度及鳞癌的分化程度相关。

Negative Ce anomaly is one of diagnostic criteria of geotectonic setting of silicalite. Silicalite in Golug, Xinrenlang and Lhazê in the Gangdisê tectonic belt is characterized by unclear negative Ce anomaly characteristic of epicontinental or neritic sediment, while silicalite in Gyüzê La-Jiaqing area is characterized by weak negative Ce anomaly characteristic of sediment in transitional belt between oceanic basin and continental margin.

硅质岩Ce异常特征是构造背景判别的最有效的手段之一，冈底斯构造带谷露、新认朗与拉孜地区的硅质岩Ce负异常不明显，属大陆边缘或浅海环境，而九子拉家青地区的硅质岩具弱的Ce负异常，属大洋盆地与大陆边缘之间的过渡环境中的沉积。

The brain waves of traumatic epilepsy in 30 cases were all abnormal, and 25 of the 30 patients had epileptiform discharges, of whom 12 showed abnormal during sleep.

因此，AEEG的昼夜记录对提高癫痫诊断的阳性率价值很大。108例CT异常的病例中，104例AEEG有异常，其阳性一致率为96.3％；45例CT正常中，30例AEEG有异常，占66.7％。

The latest geopotential model, EGM96, was employed to compute the free air gravity anomaly, geoidal separation, the average density anomalies of the crust and the uppermost mantle, and the distribution pattern of the viscous stress exerted by mantle convection over Xinjiang and its neighboring areas.

利用最新的地球重力场模型，计算了新疆及邻近地区的自由空气重力异常、大地水准面扰动异常、地壳和上地幔平均密度异常以及地幔对流引起的岩石层底界面粘滞应力场分布。

Based on the summary of newest progresses of global gravity field models, isostatic models and flexural theory of Hthosphere and making used of global gravity model (UTCSR GRACE/GFZ EIGEN-GRACE), First, I calculate geoidal anomalies with different degrees and orders, isostatic residual geoidal anomalies of Hthosphere and horizontal stress distribution in Chinese mainland and vicinity and make an interpretation with multi-levels isostatic equilibrium. Secondly, combination with surface geology and others geophysical data, I analyze detailed structure of lithosphere within various segments of the central orogenic system, respectively. Then, On the basis of making a comparative analysis with among East-Asian tomography, anomalies of geoid and satellite magnetic field for lithosphere and gravity and aeromagnetic, I propose a the lithospheric structural framework model for the Chinese mainland and adjacent area, specially the COS.

利用国际最新的地球重力场模型(UTCSR GRACE/GFZ EIGEN-GRACE)和GTOPO 30数字高程模型，笔者首先计算了中国大陆不同球谐阶次大地水准面异常、岩石圈均衡剩余大地水准面异常和水平应力场分布，从岩石圈内多层次均衡角度进行了解释推断；其次，结合地表地质和其它综合地球物理资料，分区段对中央造山系及邻区分析与解释了岩石圈细结构；然后，通过东亚地区地震层析、大地水准面异常和卫星岩石圈磁场、全国重力与航空磁力对比分析，建立了中国大陆及其邻区岩石圈，特别是中央造山系的初步结构框架。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。