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Lead to the silence of intrinsic coding genes and the expression of new genes. This brought to transgenic lines the components of gliadin different from the receptor.

基因的插入,导致原有编码基因的沉默和新基因的表达,从而使转基因株系产生了异于受体的蛋白质组分。3。

Do they exist as microdomains of heterochromatin, or are they some other form of repressive chromatin?

但是在活跃的基因中也可发现沉默基因的存在,这是否因为沉默基因存在于异染色质的 microdomain 还是他们以其它染色质的形式存在呢?

If 〓mRNA positive expression, its DNA heteroploid type display as triploid or hypodiploidy, if 〓mRNA negative expression, its DNA heteroploid type display as hyperdiploidy、tetraploid or Bistem line. These from one flank demonstrate the role of 〓 gene suppress the proliferation of malignant tumor

表达阳性者,其DNA异倍体主要表现为三倍体或低二倍体,〓表达阴性者,其DNA异倍体主要表现为高倍体、四倍体和双干系,从一个侧面显示出〓基因的抑制恶性肿瘤细胞增殖的作用。

The gene regulating sequence of human collagen type Ⅰ is located at 5'end and first intron. The carriers of reporting gene was made, and the function of promoter, enhancer and inhibiter was examined in this study. On the basis of above work, MBP ectopic expression carriers were further built. The result laid a foundation for investigating the feasibility, and validity to specially express MBP gene of human nervous system, in tendon fibroblast.

人Ⅰ型胶原基因调节序列位于5'端和第一内含子,本研究构建了带报告基因的载体并检测了其启动子,增强子和减弱子的功能,以此为基础,进一步构建了MBP异位表达载体,为探索在神经系统少突胶质细胞特异表达的人脑髓鞘碱性蛋白MBP基因转至肌腱成纤维细胞表达的可行性和有效性奠定了基础。

In addition, we presume that the role of different MMPs is distinct in various stages of EMs development. The difference of subjects which is resulted by the genetic difference of MMP-1 has the association with the risk of EMs, and the abnormal expression of protein may have relation with the development of EMs; The abnormal expression of MMP-3 has a very important role in the development of EMs; As a protein of endothelial expression, MMP-7 may participate in the development of EMs, endometrial cells with high-expression MMP-7 easily take place ectopic implantation in the blood of menstruate countercurrented and increase the risk of EMs; It is not confirmed in our study that there are the association of MMP-9 with the risk of EMs, but in view of other study, we will further evaluate the role of MMP-9 in the development of EMs.

且推测不同的MMPs基因在子宫内膜异位症发生和发展的不同阶段作用不同,MMP-1基因的遗传差异所导致的个体差异与子宫内膜异位症发病风险的个体差异相关,其蛋白的异常表达还可能与子宫内膜异位症的进展相关;MMP-3基因的异常表达在子宫内膜异位症的发展中起重要作用;MMP-7作为一个上皮性表达的蛋白,可能对子宫内膜异位症的发生起重要作用,带有MMP-7高表达的在位子宫内膜细胞更易在经血逆流中"异位"种植,增加个体子宫内膜异位症的发病风险;MMP-9虽然在本研究中没有被证实与子宫内膜异位症的发生和发展有相关性,但鉴于其它相关研究,有待于从其它方法证实MMP-9在子宫内膜异位症进展中的作用。

At the same time, however, the propensity to choose someone with slightly similar genes can also avoid the problem of outbreeding - the mixing of genes that are too different.

专家认为,人类爱选与自己基因相异的人为配偶的主要原因有两点,一是具有较大差异 MHC 基因的父母生出的后代具有较好的免疫系统,其次是避免配偶有非常相似的 MHC 基因型,这样可以避免近亲繁殖。

AIM: Pristine investigation demonstrated that TJU103 could markedly decrease graft versus host disease incidence and intensity, and obviously prolonge life span after allogenetic haemopoietic stem cell transplantation in mice.

目的:前期研究表明,吲哚亚甲基异烟腙(简称TJU103)可以明显降低异基因造血干细胞移植小鼠移植物抗宿主病的发生率和程度,明显延长小鼠移植后的生存期。

The findings were compared with those from ovarian carcinomas unrelated to endometriosis, atypical endometriosis, and ovarian endome...

结果:起源于内异症的卵巢子宫内膜样癌和卵巢透明细胞癌中各有1例检测到K-ras基因第12密码子发生突变,突变类型为GGT→TGT,即甘氨酸→半胱氨酸,其余标本均未见第12、13密码子突变。p21蛋白在与内异症相关的卵巢肿瘤。。。

They both are heterozygotic of the gene.

她们都是此基因的异基因型

FDR3 was inserted into the yeast expression vector pDBLeu and then was transferred to the yeast strain M3 mediated by PEG/LiAc and by electroporation . In the medium without copper and iron, onlywith ferric citrate , the expression of FDR3 could complement the growth defect of ctrl mutant .

把FDR3基因片段克隆到酵母表达载体pDBLeu上,然后通过电击和乙酸锂转化两种方法将重组质粒导入酿酒酵母Ctrl突变体(M3 mutant)中,采用酵母异源互补法进一步鉴定FDR3基因的功能。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

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