异基因的

Regulation of the supply of precursors and expression levels can contribute to the heterologous biosynthesis systems as well.

过度的几个基因的上游，在类异戊二烯生物合成的结果是确定和克服的瓶颈，在这方面的门路。

The activated donor-type NK cells could prevent gVHD and produce significant GVT effects and also resulted in greater hematopoietic reconstitution if they were at the initial stage of allogeneic BMT in mice. Thereafter, the activated donor-type NK cells were detrimental and could exacerbate the subsequent GVHD, these results also demonstrated that GVT and GVHD could be dissociable phenomena.

①在小鼠异基因骨髓移植的初始阶段，输注供鼠的活化NK细胞能促进造血重建，预防GVHD并同时增强移植物抗肿瘤效应；输注骨髓细胞之后，输注供鼠的活化NK细胞则起到加重GVHD的不良作用；②GVT和GVHD是能够被分开的。

There was no significant difference in the engraftment of hematopoietic stem cells between HBV infected group and control group.

在自体造血干细胞移植和异基因造血干细胞移植中包括HBsAg组和HBsAb组在内的HBV感染组白细胞恢复到1×109/L所需的平均天数与对照组比较均无统计学的显著差异（P＞0.05），乙肝病毒感染组白细胞恢复到1×109/L所需的平均天数为(14.54±5.49)d。

Analysis of genomic sequence and cDNAs from spolulating-7 h oocysts,sporozoite and the second generation merzoite implied that pre-mRNA of Etmic-2 at least generated two different proteins by alternative RNA sp licing.

与二种cDNA序列比较发现，Etmic-2基因的pre-mRNA可以通过内含子的3'端的不同剪切位点而产生不同的mRNA，生成至少两种蛋白异形体。

There is no mature scheme on haploidentical non-T-depleted transplantation in China. Prognosis of chemotherapy is poor for refractory and high-risk leukemia. Allogene hematopoietic stem cell transplantation should be applied without delay. If we can go beyond the histocompatibility leukocyte antigen boundary, HLA-haploidentical family members would became the resource of allo-HSCT donors.

目前，国内外尚无单倍型相合未去T细胞移植成熟的方案，对于难治和高危白血病患者，化疗预后是很差的，应不失时机进行异基因造血干细胞移植，如果能够跨越人类主要组织相容性抗原的限制，用人类主要组织相容性抗原半相合的亲属作为造血干细胞移植的供体，就可以彻底解决干细胞来源问题。

TGF-βbinds to a heteromeric complex of type I and type II receptors. The constitutively active type II receptor phosphorylates and activates the type I receptor which phosphorylates Smad2 and Smad3 (receptor-associated Smads). Receptor-associated Smads bind the common mediator Smad4 and are translocated to the nucleus, where they associate with DNA-binding cofactors to modulategene transcription.

TGF-β与其效应细胞表面的Ⅱ型受体TβRⅡ和Ⅰ型受体TβRⅠ形成的异源二聚体结合，相继激活TβRⅡ和TβRⅠ，活化的TβRⅠ再进一步活化Smad2和Smad3，磷酸化的Smad2/3必须与Smad4结合形成复合物，才能进入细胞核，调节靶基因的转录[6]。

This study was purposed to investigate the dynamic change of clonal proliferation of T cell receptor V subfamilies in peripheral blood of patients received allo-hematopoietic stem cell transplantation and to analyze the relationship between T cell clonal proliferative changes and GVHD.

本研究观察异基因造血干细施移植患者外周血T细胞受体Vβ亚家族克隆性增殖的动态变化，分析T细胞的克隆性演变与GVHD的关系。

This study was purposed to investigate the dynamic change of clonal proliferation of T cell receptor V subfamilies in peripheral blood of patients received allohematopoietic stem cell transplantation and to analyze the relationship between T cell clonal proliferative changes and GVHD.

本研究观察异基因造血干细胞移植患者外周血T 细胞受体 Vβ亚家族克隆性增殖的动态变化，分析T细胞的克隆性演变与GVHD的关系。

The homeobox gene is in close relation to develop...

结论同源异形框基因的差异表达表明正常成人和胎儿皮肤的发育生物学状态存在差异，可能是胎儿和成人皮肤不同创面愈合方式的根本原因。

ALA-PDT alleviated GVHD following allo-BMT and preserved GVL in ALL mice One-way mixed lymphocytes predisposed with ALA-PDT and marrow cells from the donors were infused into ALL mice. The body weight increase, haematogenesis recovery and survival time were better then all the other groups.

ALA-PDT减轻急性淋巴细胞白血病(acute lymphoblastic leukemia，ALL)小鼠同种异基因骨髓移植后GVHD反应，并且保留了GVL效应将经过ALA-PDT处理过的单向混合淋巴细胞联合供鼠的骨髓细胞输注给ALL小鼠体内，ALL受鼠的体重增长情况、造血功能恢复情况及无病生存时间等指标明显好于对照组。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。