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This study was purposed to investigate the dynamic change of clonal proliferation of T cell receptor V subfamilies in peripheral blood of patients received allo-hematopoietic stem cell transplantation and to analyze the relationship between T cell clonal proliferative changes and GVHD.

本研究观察异基因造血干细施移植患者外周血T细胞受体Vβ亚家族克隆性增殖的动态变化,分析T细胞的克隆性演变与GVHD的关系。

This study was purposed to investigate the dynamic change of clonal proliferation of T cell receptor V subfamilies in peripheral blood of patients received allohematopoietic stem cell transplantation and to analyze the relationship between T cell clonal proliferative changes and GVHD.

本研究观察异基因造血干细胞移植患者外周血T 细胞受体 Vβ亚家族克隆性增殖的动态变化,分析T细胞的克隆性演变与GVHD的关系。

Within three years following-up, 5 patients with NHL were survival, but one case of NHL died at the 2 months after auto-PBSCT, one patient suicided. From 4 cases received allo-PBSCT, one patiant with NHL was died at 79 days later, one patient with chronic lymphoblastic leukemia was surviving, another 2 cases of acute lymphoblastic leukemia were dead at 17 months and 54 days respectively after allo-PBSCT.

随访3年,5例NHL患者无病生存,1例NHL患者于移植后2个月死亡,1例自杀;4例接受异基因造血干细胞移植的患者中,1例非霍奇金淋巴瘤移植后79天死亡,1例慢性淋巴细胞白血病患者无病生存,2例急性淋巴细胞白血病患者分别于移植后第54天、第17个月死亡。

Objective To investigate the distributionand the chimerism features after infusion of allogeneic bone marrow cells in rats.

目的 研究大鼠异基因骨髓细胞输注后在受者器官的嵌合状态及分布规律。

To analyze the relationship of GVHD and chimerism;5. To analyze the relationship of blood group shifting and chimerism.

寻找异基因造血干细胞稳定植入的标志和移植物被排斥或疾病复发的分子学先兆; 4。

The aim of this study was to analyze the hematopoietic chimerism after non-myeloablative allogeneic peripheral blood stem cell transplantation. 28 patients received NAPBSCT were evaluated.

本研究旨在探讨非清髓异基因外周血造血干细胞移植后造血嵌合体的临床意义。

Objective To investigate the clinicopathological characteristics of nephrotic syndrome after allogeneic bone marrow transplantation.

目的探讨异基因骨髓移植后肾病综合征的临床和病理特点。

A protocol for nonmyeloablative allogeneic hematopoietic stem-cell transplantation that includes total-body irradiation and treatment with alemtuzumab and sirolimus can achieve stable, mixed donor-recipient chimerism and reverse the sickle cell phenotype.

包括全身照射以及阿仑单抗和西罗莫司治疗在内的非清髓性异基因造血干细胞移植方案,可取得稳定的混合供者—受者嵌合性,并且可逆转镰状细胞表型。

Allogeneic hematopoietic stem cell transplantation is one of the most valid methods for the treatment of malignant and refractory haematological diseases.

异基因造血干细胞移植是当今治疗恶性和难治性造血系统疾病的最有效手段之一,移植物抗宿主病是影响allo-HSCT疗效的关键。

The clinical data of 75 patients with haematological malignancies undergoing allo-HSCT from May 1996 to March 2007 was analyzed, factors possibly correlated with the development of oral mucositis were assessed.

探讨进行异基因造血干细胞移植患者口腔黏膜炎的发生及其危险因素。

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