异基因

The peroxisome proliferator-activated receptors play an important role in adipocyte differentiation and fatty acid metabolism, activation of PPAR may induce the differentiation of adipocyte,influence the expression of genes involved in lipogenesis and fatty acid oxidation,eventually lessen ectopic fat accumulation and improve the impaired insulin signaling,so the medicine which targets to the control point of FFA metabolism would be hopeful in the treatment of a cluster of metabolic abnormalities resulted from insulin resistance.

过氧化物酶体增殖物激活受体在脂肪细胞分化、脂肪酸代谢中起重要作用，PPAR及其所调控基因的激活可促进脂肪细胞分化、减少脂质产生、增加脂肪酸氧化，从而减少脂质的异位沉积，进一步改善损伤的胰岛素信号转导通路，逆转胰岛素抵抗。针对脂肪酸合成及氧化的关键调控点的药物可能是今后治疗胰岛素抵抗引发的一系列代谢异常的新的靶点。关键词过氧化物酶体增殖物激活受体；脂肪酸代谢；胰岛素抵抗

The enzyme activity of LpsA2 was increased to 250% or above by 1 mmol/L Co2+, Hg2+ and Zn2+, respectively. The activity was also elevated to 110.7% and 138.0% by 15% dimethylformamide and dimethyl sulfoxide, and 352.7% and 189.7% by 0.1% and 1% Span-20, respectively. The enzymatic properties of LpsA2 from S. avermitilis were characterized that may provide the fundament to the screening of bio-engineered bacteria and the industrial applications in food processing and drug synthesis.

avermitilis的脂肪酶基因lpsA2进行了异源表达和酶学功能鉴定，不仅为脂肪酶的研究积累了更多数据，也为具有优良性能的脂肪酶生物工程菌的筛选奠定了基础，更为其在食品加工、药物合成等工业生产中的应用提供了依据。

Regulation of the supply of precursors and expression levels can contribute to the heterologous biosynthesis systems as well.

过度的几个基因的上游，在类异戊二烯生物合成的结果是确定和克服的瓶颈，在这方面的门路。

According to either sequence data sets or gene arrangement features at both gene junctions, Brachyuran crabs were monophyletic and divergent between Heterotremata and Thoracotremata. Potamoidea represented by S.

本文基于基因序列和排列数据的系统发生分析都支持短尾类是一单系群；异孔类和胸孔类互为姐妹群；以长江华溪蟹为代表的溪蟹总科与扇蟹总科、梭子蟹总科有较近的亲缘关系。

The objective of the present study was to investigate the effect of energy intake during the dry period on the expression of Pyruvate carboxylase and Phosphoenolpyrevate carboxykinase mRNA in the liver of periparturient diary cows.

本研究目的在於观测乾奶期不同能量摄入对围产期健康奶牛肝糖异生关键酶－丙酮酸羧化酶和磷酸烯醇式丙酮酸羧激酶基因表达的影响。

By splicing in genes from other bugs, the company was able to engineer synthetic metabolic pathways—ones that do not exist in nature—that enable the bacteria to produce isoprene from the sugars found in plant materials such as sugar cane, corn cobs and switchgrass, a tall-growing variety native to North America.

Genecor的科学家们将其它细菌的基因拼接到大肠杆菌上，从而在大肠杆菌上制造出一种自然界中不存在的代谢物合成途径。它使细菌能从植物材料中的糖分生产出异戊二烯——这些含有糖类的植物包括甘蔗、玉米芯，还有原产于北美洲的高个儿品种柳枝稷。

I also found that multi-domain polypeptide genes are less dispensable but more duplicable than single domain polypeptide genes.

可能的情况是当一个异复合体次单元基因被剔除的时候，整个复合体的功能都会受到影响。

Posterior pituitary ectopia is a developmental disorder of the porencephalon, thought to be genetic in origin.

垂体后叶异位是一种前脑发育畸形，被认为是遗传学病变，牵涉到多个基因。

Pial basement membrane breaches and glia limitans disruptions are the underlying causes of cerebellar granule neuron ectopia in POMGnT1 knockout mice and that migration into the IGL is not required for their differentiation.

1。在POMGnT-1基因敲除小鼠中，导致小脑颗粒细胞异位的原因是软脑膜基底膜层和胶质细胞的界膜的破裂，而颗粒细胞迁移到IGL并非是分化所必需。

The first pathogenetic gene identified is α-synuclein, but its phathological mechanism is unknown. In previous study, it's demonstrated that all synuclein isoforms expressed massively in early embryologic development of the central nervous system.

先前有研究指出所有的synuclein异构型在胚胎发育早期即在中枢神经系统被大量表现，显示这一类基因对中枢神经系统的发育可能是很重要的，但是研究synuclein在胚胎早期发育方面的相关研究则较少。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失