异基因

"Epistasis:an interaction between nonallelic gene s, especially an interaction in which one gene suppresses the expression of another."

异位显性：非等位基因的相互作用，尤其是一个基因对另一个基因所表现的显性现象。

"Epistasis:an interaction between nonallelic genes, especially an interaction in which one gene suppress es the expression of another."

异位显性：非等位基因的相互作用，尤其是一个基因对另一个基因所表现的显性现象。

Since then, the gene localization has developed from simply being described as at the euchromatin region and heterochromatin region to more complicated nuclear localization. Therefore, the gene regulation attracted more attention now.

因此基因在细胞核内的定位就由原来简单认为的异染色质区和常染色质区发展得更为深入了，基因在细胞核内的定位以及位置的变化与基因表达调控之间的关系也越来越受到重视。

Forced expression of fez induces ectopic expression of dlx2 and dlx6, two genes involved in brain development.

通过显微注射含有Fez基因的DNA或mRNA使该基因在野生型斑马鱼胚胎中超表达，可以诱导两个与脊椎动物前脑发育相关的基因dlx2和dlx6发生提前和异位的表达。

Lead to the silence of intrinsic coding genes and the expression of new genes. This brought to transgenic lines the components of gliadin different from the receptor.

基因的插入，导致原有编码基因的沉默和新基因的表达，从而使转基因株系产生了异于受体的蛋白质组分。3。

Do they exist as microdomains of heterochromatin, or are they some other form of repressive chromatin?

但是在活跃的基因中也可发现沉默基因的存在，这是否因为沉默基因存在于异染色质的 microdomain 还是他们以其它染色质的形式存在呢？

The gene regulating sequence of human collagen type Ⅰ is located at 5'end and first intron. The carriers of reporting gene was made, and the function of promoter, enhancer and inhibiter was examined in this study. On the basis of above work, MBP ectopic expression carriers were further built. The result laid a foundation for investigating the feasibility, and validity to specially express MBP gene of human nervous system, in tendon fibroblast.

人Ⅰ型胶原基因调节序列位于5'端和第一内含子，本研究构建了带报告基因的载体并检测了其启动子，增强子和减弱子的功能，以此为基础，进一步构建了MBP异位表达载体，为探索在神经系统少突胶质细胞特异表达的人脑髓鞘碱性蛋白MBP基因转至肌腱成纤维细胞表达的可行性和有效性奠定了基础。

In addition, we presume that the role of different MMPs is distinct in various stages of EMs development. The difference of subjects which is resulted by the genetic difference of MMP-1 has the association with the risk of EMs, and the abnormal expression of protein may have relation with the development of EMs; The abnormal expression of MMP-3 has a very important role in the development of EMs; As a protein of endothelial expression, MMP-7 may participate in the development of EMs, endometrial cells with high-expression MMP-7 easily take place ectopic implantation in the blood of menstruate countercurrented and increase the risk of EMs; It is not confirmed in our study that there are the association of MMP-9 with the risk of EMs, but in view of other study, we will further evaluate the role of MMP-9 in the development of EMs.

且推测不同的MMPs基因在子宫内膜异位症发生和发展的不同阶段作用不同，MMP-1基因的遗传差异所导致的个体差异与子宫内膜异位症发病风险的个体差异相关，其蛋白的异常表达还可能与子宫内膜异位症的进展相关；MMP-3基因的异常表达在子宫内膜异位症的发展中起重要作用；MMP-7作为一个上皮性表达的蛋白，可能对子宫内膜异位症的发生起重要作用，带有MMP-7高表达的在位子宫内膜细胞更易在经血逆流中"异位"种植，增加个体子宫内膜异位症的发病风险；MMP-9虽然在本研究中没有被证实与子宫内膜异位症的发生和发展有相关性，但鉴于其它相关研究，有待于从其它方法证实MMP-9在子宫内膜异位症进展中的作用。

At the same time, however, the propensity to choose someone with slightly similar genes can also avoid the problem of outbreeding - the mixing of genes that are too different.

专家认为，人类爱选与自己基因相异的人为配偶的主要原因有两点，一是具有较大差异 MHC 基因的父母生出的后代具有较好的免疫系统，其次是避免配偶有非常相似的 MHC 基因型，这样可以避免近亲繁殖。

In summary, FA is a sensitive indicator of the environmental stress and ecological risks induced in the parasitoid by exposure to Bt-cotton.

Bt棉对异色瓢虫也无影响，但在取食了转Bt基因棉的棉铃虫体内发育的寄生蜂较之对照表现为卵-结茧历期延长、茧重减轻、成虫寿命缩短，而其FA与个体结茧-出蜂历期呈显著正相关，表明FA是反映转Bt基因棉对斑痣悬茧蜂不利影响的敏感指标，可望成为转Bt基因棉生态风险的早期预警指标。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失