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异倍体

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Results DNA analysis showed that almost all the CISs and EMICs were diploidy , while 90% of invasive carcinomas were aneuploidy.

结果 DNA倍体分析表明CIS、EMIC和浸润性癌不同,前两者几乎都是二倍体,而后者 90 %为异倍体

That PI and the percentage of the cells in s-phase of the borderline/malignant and heteroploid/aneuploid tumors were higher ted to higher mortality and relapse rate as well as the corresponding risk. Because of the changable characters and dissociative phenomenon of the tumor, the measurement of PI and the percentage of cells in s-phase may be disturbed in few of diploid tumor and in part of double DNA stem ones. Therefore other paramet- ers should be added to analyse before making any conclu- sion.

交界性和恶性、异倍体或非整倍体肿瘤的PI和S期细胞百分率较高,病死加复发率和相对危险性增加;由于肿瘤的异质性和"分离现象",对于少数2倍体肿瘤和部分双DNA干系肿瘤PI和S期细胞百分率的测定易受干扰,故应结合其它参数综合分析。

Result:The content of cholesteatoma tissues and postauricular skin specimens are a normal euploid.

结果:胆脂瘤上皮细胞和外耳道上皮细胞的核型均为二倍体,未见异倍体

RESULTS: Of the 53 patients, 32 (60.4%) had DNA diploid and 21 (39.6%) had DNA heteroploid.

结果:53例患者中,二倍体32例(60.4%),异倍体21例(39.6%)。

The NPC patients with DNA heteroploid are more easily to emerge distant metastases than those with DNA diploid.

采用流式细胞术检测新鲜组织细胞的DNA倍体性和临床分期一样可以预测鼻咽癌患者的预后;DNA异倍体患者比二倍体患者更容易出现远处转移而导致治疗失败。

Of them are treated with immunohistochemistry modus to detect Ki-67 expression; 4. Use SPSS13.0 for windows statistics software to chisquare inspection. Results: through detecting, heteroploid pecentage and Ki-67 positive expression of the patient who suffered breast cancer grouped in the zhengqi-weak-evil-strong type is the highest in the three typies(69.4%,94.4%).

结果:乳腺癌患者术前辨证为正虚毒炽者DNA倍体异倍体、Ki-67阳性出现率最高(69.4%,94.4%),冲任失调组次之(41.0%,58.3%),肝郁痰凝组最低(23.5%,12.5%),经统计学处理,三组之间有显著差异(P.05);正虚毒炽组S期细胞比例为高度的几率最高(58.3%),冲任失调组和肝郁痰凝组无显著差异(17.9%,23.2%)。

The expression rates of CD44V5+ CD44V6+, cerbB-2+ cells in patients with metastasis, multi-metastasis nodes, DNA heteroploid, SPF elevated, and Apo decreased were higher than those of patients with non-metastasis, only one-metastasis node, DNA diploid, SPF non-elevation and Apo non-decreasing, respectively (P.01 or 0.05), while nm23+, DCC23+ and p16+ were contrary.

肿瘤转移者、多器官转移者、DNA异倍体者、SPF增高者、APO不减低者的CD44V5+、CD44V6+、cerbB-2+细胞表达率均显著高于未转移者、单器官转移者、DNA二倍体者、SPF不增高者、APO不减低者(P.01或0.05)。而nm23+、DCC+、p16+细胞的表达率与此相反。

Results The deˉtection ratio of heteroploidy in leukemia children was more than that in non-leukemia.Four of12patients with non-leukemia were heteroploidy,2of4were precancerous lesion.

结果 白血病组异倍体检出率明显高于非白血病组。12例非白血病中4例异倍体,其中2例癌变。

The heteroploidy rate of PC group was 65.71%,NP group and BPH group were DNA diploid,the cell proliferous ratio of PC group was different with NP,BPH groupP

PC高分化组的异倍体率低于中、低分化组(P.05)。DNA异倍体、高S期细胞比率是前列腺癌的重要生物学特性,也可作为鉴别PC、BPH的参考指标。

Methods The exfoliated cells from 84 cases hydrothorax and ascites(including 35 cases of malignant tumor group and 49 cases of non-tumor group) were analyzed in DNA ploid by FCM, the results were compared with the method of exfoliative cytology.

方法应用流式细胞仪对84例患者(恶性肿瘤组35例,非恶性肿瘤组49例)的胸腹水脱落细胞进行DNA倍体分析;以检出异倍体为恶性肿瘤判断标准,并与胸腹水常规脱落细胞学涂片检查结果比较。

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