异位移植

14Th week after injury, the reorganization of labelled neurons' distribution was found in the autograft group, but only one case in the NTN/PGLA group. Conclusion Local application of PGLA tube with neurturin can recover the axoplasm flow of regenerated nerve fibers, its long-term effect can match that of the nerve autograft, and collateral axonal branching occurred less.

应用NTN/PGLA导管的修复能够和自体神经移植修复一样恢复神经缺损的连续性和逆行轴浆运输功能，后期效果相当；应用NTN/PGLA导管修复后神经元分布异位明显少于自体神经移植修复，提示较少发生轴突误向再生，减少面肌联带运动的发生。

Objectives: Through studying the distribution of Sppan acetic ether extract in donor's hearts of rats and its effect on IL-1β in blood, to approach the distribution target ability of sappan in donor's hearts, and its possible immune resist mechanism.

目的：通过研究苏木乙酸乙酯提取物在同种异位心脏移植大鼠供体心脏的分布情况和对小鼠外周血IL-1β活性影响，探讨苏木免疫活性部位在供体心脏分布的选择性及其免疫抑制作用机理。

Objective: To investigate the risk of ectopic pregnancy after in vitro fertilization and embryo transfer.

目的：探讨体外受精-胚胎移植后异位妊娠发生的危险因素。

Cardiac transplantation ; Heterotopia ; Chronic rejection ; Animal model ; Rat

心脏移植；异位；慢性排斥；动物模型；大鼠

Abstract］ Objective: To establish a simplified and useful heterotopy heart-lung transplantation rat model for studying of the mechanism of transplantation rejection and cure the rejection in animal model.

目的：建立一种操作简单、可行的大鼠异位心肺联合移植模型，以利于移植排斥反应机制的研究及其实验性治疗研究。

Methods Sibling pigs were used, and the right liver lobe of the donor pig was transplanted into right subhepatic space of the recipient to establish the model of heterotopic partial liver transplantation. Hemodynamic monitoring was carried out by catheterizing from right superficial cervical vein to measure heart rate, mean arterial pressure, central vein pressure, pulmonary arterial wedge pressure, mean pulmonary arterial pressure and cardiac output.

采用同窝猪建立右肝下异位部分肝移植模型，从右颈浅静脉切开插管，监测心率、平均动脉压、中心静脉压、肺动脉楔压、心排出量、平均肺动脉压等血液动力学指标，观察异位部分肝移植术中血液动力学变化规律。

Methods: Heterotopic abdominal heart transplantations of Wistar and SD rats were performed by using Ono's method with modification of preparation of recipients, donor cardiectomy and donor transplantations.

对传统Ono术式的受体准备、供心切取、供心移植等环节进行改良，建立Wistar和SD大鼠的腹部异位心脏移植模型。

Bronchiolitis obliterans is the most disturbing complication following lung transplantation. This study is to investigate whether prolonged ischemia would promote early establishment of BO Material and Methods Left lower lobectomy was performed from miniature swine. Lung fragments, each measured 1 cm3, contained terminal bronchioles were auto- or alloimplanted into the subcutaneous area around the nipples. These lung implants were removed on 7th; 14 th; 21 th; 28th and 56th days and were fixed for histological examination. Experimental group using the same procedures but the left lower lobe was washed with 4.degree.C Lactate ringer via interlobar artery before lobar bronchus was resected.

肺移植后的阻塞性细支气管炎是肺移植后最困扰的并发症，本研究的目的希望了解缺血时间的延长是否会促进阻塞性细支气管炎提早发生实验方法施行小猪的左下肺叶切除手术，将取下的肺切成含终末支气管1 公分立方的肺小块，以自体及异体异位肺移植模式，将植入小猪皮下的肺小块於植入后第7、14、21、28 及56 天取下，在病理下检示其病理变化，并利用原位灌留的方式将左下肺叶以4℃林格氏液灌洗后再摘除之，观察有无灌洗对於阻塞性细支气管炎生成的影响。

Results:(1) CBC possesses a natural trabecular structure. Its components is similar to the mineral of bone.(2) CBC has great cellur biocompatibility. It can promote cell adhesion, proliferation and secretory while needn t modification.(3) In nude mice, the ectopic osteogenesis of MCCAB was obvious which was better than that of CBC alone and the new bone formation increased in pace with time. In the MCCAB, both intramembranous and cartilaginous osteogeneses were seen but the former dominated.(4) When MCCAB was autotransplanted intramuscularly, the osteogenesis was much better than that of negative control groups.(5) The MCCAB can repair autogenous calvaria defects effectively and the effect was much better than that of CBM alone and blank group. Conclusion:(1) CBC possesses good biocompatibility, osteoconduction and porous structure, can be used as scaffold material for constructing of tissue engineering bone.

结果：(1)CBC具有天然的多孔网状结构，最大程度地保持了骨矿的微结构特征，可以作为骨组织工程的支架材料；(2)CBC细胞亲和性好，不需作修饰即能促进成骨细胞的粘附、增殖和分泌活动；(3)MSO/CBC复合人工骨在裸鼠皮下异位成骨作用明显，兼有膜内成骨和软骨内成骨的特点，成骨效果明显优于单纯CBC植入组；(4)MSO/CBC复合人工骨兔自体肌袋异位成骨作用明显，血管化充分，成骨效果明显优于单纯CBC植入组；(5)MSO/CBC复合人工骨修复兔颅骨临界性缺损效果好，明显优于单纯植入CBC组和空白对第四旱区大学硕士学位论文一照组，可以作为骨移植替代材料用于骨缺损畸形修复。

This study retrospectively analysed the clinical data of 1134 cases after IVF-ET and 317 cases after cryopreservation and thrawing embryo transfer.

回顾性分析7年间施行IVF-ET(包括卵胞浆内单精子显微注射)1134个周期及冻融移植317个周期的资料，分析不孕原因及胚胎移植距宫底的深度与异位妊娠的关系。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。