异于...

Objective: The purpose of our studies are gaining a better insight into the effect of genistein on mesangial cell"s phenotype change and ECM expression plus degradation under DN circumstances.We add genistein with different concentrations in high glucose cultured rat mesangial cells;feed DM rats with the single concentration genistein for different days;to explore the expression of SMemb,the mark of mesangial cell"s hypertrophy phenotype change;to examine the synthesis of Fn as well as the change of the balance between MMP-2 and TIMP-l;to comprehend its effect on renal pathological changes of DM rats and some related factors;trying toexplore the possible mechanisms.Through these studies,we will have some information about the experimental value of genistein in DN field.

目的：为了研究金雀异黄素对DN环境下大鼠MC肥大表型转换标志物SMemb和ECM分泌及降解的影响，我们拟在细胞水平以不同浓度的金雀异黄素作用于高糖培养下大鼠MC，在动物水平以同一浓度的金雀异黄素作用于DM大鼠不同时间，观察细胞表型转换标志物SMemb、ECM主要成分Fn、ECM降解酶系统基质金属蛋白酶—2(MMP-2)／基质金属蛋白酶抑制剂—1(TIMP-1)表达的变化，同时观察金雀异黄素对DM大鼠肾脏病理及影响肾脏病进展的糖脂代谢紊乱的影响，并进一步探讨金雀异黄素发挥作用的可能机制；为明确金雀异黄素在DN治疗中的地位及意义提供实验依据。

Results 10 cases of PEP occurred after laparoscopic surgery,and 5 happened at laparotomy. 3 cases after salpingectomy,and 12 after after conservative operation of tubal pregnancy.

结果 持续性异位妊娠发生于腹腔镜手术后有10人，发生于开腹手术5人，持续性异位妊娠发生于输卵管切除术后3人，发生于保留输卵管后的有12人。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果：1、哇巴因作用于晶状体钠泵后，光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙，电镜下全层细胞空泡化、线粒体肿胀出现髓样结构，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后，光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离，电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后，光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整，电镜下细胞器丰富、细胞功能旺盛，RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后，光镜下晶状体质膜完整、细胞排列紧密规整，电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝，RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后，光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化，电镜下囊侧膜内有高电子密度带、细胞核仁丰富，RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后，光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏，电镜下质膜变性、线粒体肿胀，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

On the contrary, they two help us realize that romps oriented towards past or future are two fundamentally different expressions of human life.

尽管互联网时代流动性成了健康的标准，这使我们拥有了一种异于传统的生活形式，但它仍旧是历史。

In addition, the two surface of the cementing layer is not always strictly parallel. And therefore its deflection angle and transmissivity is different from the value of the order.

另外，胶合层的前后表面并不总是严格平行，因此其偏向角和光强透射比要异于正常情况下的值。

Because of the special origin of biogenic gas, the evaluation of its source rocks is different from conventional hydrocarbon source rocks.

生物气成因的特殊性，使得对生物气源岩的评价也有异于常规烃源岩。

Men differ from brutes in it that they can think and speak.

人之所以异于禽兽，就在能思想能说话。

This is a One Piece Straw Hat pirates Mission Swordsmen Solon's confession, there are different from ordinary people's capacity for liquor, but he also claimed that a true swordsman must not be drunk themselves.

这是海贼王草帽海贼团的剑士索隆的自白，有异于常人的酒量，但他也声称一位真正的剑士绝对不能将自己灌醉。

The Athenian metics with their special status played the special indispensable historical role for the prosperity and stabilization of the Athenian polis.

作为有自由之身却无政治权利的社会群体，外邦人在雅典城邦的发展过程中发挥了异于公民和奴隶的特殊历史作用。

Self-sacrificial maternal love is a virtue,which but is inherited from our animal ancestors and we seem to be unable to take pride in it for our cattles have it too.the instinct love is just animal love and that is not why human beings are different from animals.the reason is human beings have a higher-level cognition and understanding.this perspective might be seen as something too rational,too cold,in a word,something lack of "humanity"------it is actually more "humane" in that it shows the dissatisfaction for the animal love as a standard.

自我牺牲的母爱是美德，可是这种美德是我们的兽祖先遗传下来的，我们的家畜也同样具有的——我们似乎不能引以自傲。本能的仁爱只是兽性的善。人之所以异于禽兽者并不在此。人之所以为人，全在乎高一等的知觉，高一等的理解力。此种论调或者会被认为过于理智化，过于冷淡，总之，缺乏&人性&——其实倒是比较&人性&的，因为是对于兽性的善的标准表示不满。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。