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In HCI base solution lsonsorbid 5 - mononitrate have two reductive peak at - 0.50 V and-0.88 Vvs.

在盐酸底液中,单硝酸异山梨酯在汞电极上于-0.50 V 和-0.88 Vvs。

The conclusions are as follows:(1) Neologisms in each Huayu region can be classified into two major categories:self-originated and others-originated,among which the new-born words are "absolute new words" and the inherited word are "relative new words",and there are also others-originated elements in the morphemic and sense systems of new words;(2) Variation can be seen in the morpheme,formation,building and sense of new words in Huayu regions,besides individuals of new words;(3) Aggregation of current new words and compound words with one common morpheme and a same construction,together with the aggregation of synonyms and that of different senses in polysemies,reflect the relevance of the systems of new words in Huayu regions in their variation;(4) Regular participation of hinting sense of a formation element in forming and building new words is an important way of producing new sense of morpheme,and an important reason for the current emergence of words with more than one new senses;(5) Compared with ordinary words,the productivity of ways of word formation in forming new words both in general and of a particular class will change and new ways of word formation appear in Huayu regions;(6) The semantic collocation of the verbal morpheme of new verbs in a phrase has a great influence on the location of its structural center,and the complex syntactic behaviors of new verbs are related to the different processes of argument integration;(7) The processes of building new words with the same meaning differ in levels of approaches to motivation cognition,perspectives of motivation cognition,morpheme motivation and morpheme expression,etc.;(8) The lexical interaction in Huayu regions results in lexical subsystem intersections of current new words across two,three and four regions.

本文的主要结论是:(1)各华语区新词均可分为&自源新词&和&他源新词&两大类,其中的新生词和传承词分属&绝对新词&和&相对新词&,新词语的词素、词义系统中也含有他源成分;(2)除词语个体外,华语区新词在词素、构词、造词、词义等方面均体现了某种程度的变异:(3)通用词语聚合、同素同构词聚合、同义异形词聚合与一词多义聚合集中反映了各华语区新词语系统在变异中的关联;(4)构词单位经常提示词义参与构造新词是产生新语素义的重要途径,也是当代多新义词现象的重要成因;(5)相对于一般词语,构词方式在新词语中的总能产性和在某一词类中所体现的能产性都有所变化,华语区也产生了新的构词方式;(6)新动词的动素在短语中的语义搭配对结构核心的位置有很大影响,新动词的复杂句法表现与不同的论元整合过程有关;(7)同义新词造词过程的差异包括理据认知途径、理据认知角度、词素理据和词素表达等不同层面;(8)华语区的词汇互动形成了双区、三区和四区通用新词等词汇子系统交集,作为华语核心,普通话所含纳的通用词语多于各区域变体。

It was conducted to study the renewal method of multiflorous bean seed regeneration in genebank.

取材于有特殊经济价值、常异花授粉作物多花菜豆,研究基因库中种子繁殖更新方法。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病,不管是急性淋巴性白血病或是急性骨髓性白血病,在染色体11q23部位有染色体易位的情况;这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是,单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%;并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且,这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后,而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖,遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以,白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

Both DO and ORP are used as fuzzy control parameters of SBR1 aerobic duration, which can maintain heterotrophs for organics removal and Nitrosomonas in different reactors and make TSSBR system operate stably and reliably.

将DO和ORP联合作为SBR1阶段好氧反应时间的模糊控制参数,可使去除有机物的异养菌和硝化菌存在于不同的反应器内,保证两段SBR系统长期稳定运行。

Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果:倒置显微镜和透射电镜观察显示,经SAHA处理的细胞增殖速度显著减慢,细胞体积增大,细胞核较小,形状较为规则,核仁数量减少、体积变小,核内常染色质增多而异染色质减少,核质比例减小,细胞质内线粒体数量增多、线粒体嵴发达,高尔基体较为典型,粗糙型内质网增多,呈现出与正常上皮细胞相似的形态变化;MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用,并有明显的剂量依赖和时间依赖关系;免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达;流式细胞仪检测结果显示,SMMC-7721细胞经SAHA处理后,G0/G1期细胞明显增加,S期细胞则明显减少,细胞被阻滞于G0/G1期;RT-PCR检测结果表明,SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加,24h后更为明显。

The sample was mixed with norleucine as the internal standard, then derivatized with phenylisothiocyanate and analyzed on a Kromasil C18 column at 38 ℃, using gradient elution with detection at 254 nm.

以正亮氨酸为内标物,异硫氰酸苯酯为柱前衍生剂,用C18色谱柱在柱温38 ℃下采用二元梯度洗脱,于254 nm波长处检测。

In this part, the densities of sodium benzoate, sodium nitrobenzoate, sodium chlorobenzoate and sodium methylbenzoate in DMFwater mixed solvents have been measured at 298.15K with an Anton Paar Model 55 densimeter. From these densities, apparent molar volumes and partial molar volumes have been calculated, transfer volumes from water to DMF-water mixtures and substituent contributions to the transfer volumes have also been obtained. Solvent and substituent effects are discussed in detail. The Scaled Partical Theory has been applied to the ternary solutions to evaluate the partial molar volumes of cavity formation and the volumes change associated with solute-solvent interaction.

选择了含有取代基团的芳香类有机电解质,主要是苯甲酸钠、硝基苯甲酸钠、氯苯甲酸钠和甲基苯甲酸钠的邻、间、对同分异构体作为研究对象,用DMA 55型振荡管密度计测定了它们在不同质量百分数组成的DMF-水混合溶剂中的密度,利用这些密度数据,计算了表观摩尔体积和偏摩尔体积,得到了这些单取代苯甲酸钠从水到DMF-水混合溶剂中的迁移偏摩尔体积及苯环上不同位置的取代基对迁移偏摩尔体积的贡献值,讨论了溶剂效应和取代基效应,并将定标粒子理论应用于此三元电解质溶液中。

His team also examined phenethyl isothiocyanate, a constituent of cruciferous vegetables such as broccoli, on ovarian cancer cells.

斯里瓦斯塔瓦的研究小组还检测分析了存在于花椰菜等十字花科蔬菜中的异硫氰酸苯乙酯对卵巢癌细胞产生的作用。

Objective:To eliminate the rejective reaction of host-versus-graft in the SRCA,a new kind of immunosuppressed mice model was established.

:目的:建立一种适用于肿瘤药敏人癌肾包膜下移植法的免疫抑制小鼠模型,克服普通小鼠的免疫排异反应及裸鼠费用昂贵的缺陷。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。