异丙胺

Then Doripenem came into the market in the July ,2005. We studied the synthesis of Doripemen.Firstly, we synthesized the chemical 2 from the starting material------o-hydroxylphenylacylamine through Reformastky reaction, alkylation, Diekmann reaction, enolization, esterification and etc. Secondly, we synthesized the chemical 3 from L — hydroxylproline through the protection of carboxyl, amidogen and hydroxyl group, reduction by NaBr, SN_2 substitution and Mitsumobu reaction.

我们以水杨酰胺为起始原料，经Reformatsky反应、烷基化、Diekmann环合、烯醇化、酯化等反应合成双环母核2；再从L-羟基脯氨酸出发，经酯化保护羧基、保护氨基、保护羟基、硼氢化还原酯得醇、Sn2取代和Mitsumobu反应等合成巯基侧链3；最后由化合物3经脱保护、水解得硫醇，和化合物2在二异丙基乙基胺的作用下缩合，最后Pd／C催化脱保护，历经16步反应最终得到产物多尼培南。

Methods the normal desensitization with antivenin 1-2 Ampere and dexamethasone 10mg and 0.9 sodium chloride 250ml intravenous drips take off the method 19 among those example sufferer apper the severe erythra and allergic shock during the period of cure adopting comprehensive treatment for promethazine and dexamethasone and 10 calcium gluconate the blood pressure reduced over lower add to use dopamine and metaraminol etc.

常规行抗蛇毒血清1-2支地塞米松10mg0.9NS250ml静脉点滴的脱敏方法，其中19例患者在治疗过程中出现全身性皮疹及过敏性休克，采用异丙嗪、地塞米松、10葡萄糖酸钙，血压下降过低者，加用多巴胺、间羟胺等综合治疗。

The results showed that the thermo-sensitivity of hairy PNIPA changed obviously in the presence of hairy PAA as polyelectrolyte.4-cyanopentanoic acid dithiobenzoate as soluble reversible addition-fragmentation chain transfer agent was directly added into the above PS particles with photo-initiator on the surface and NVP or NIPA as monomer.

其次，将水溶性RAFT试剂直接引入上述光引发聚合体系，探讨连续相中RAFT试剂的存在对微球表面N-乙烯基吡咯烷酮或N-异丙基丙烯酰胺聚合的影响，考察了RAFT试剂对聚合过程中微球壳层高分子毛发厚度和单体转化率变化趋势。

Poly(N-isopropylacrylamide-co-2-hydroxyethyl methacrylate)/clay hydrogel was copolymerized with NIPA and HEMA cross-linked by clay to form a new kind of nanocomposite hydrogel P(NIPA-co-HEMA)/clay was obtained.

以无机粘土为交联剂制备了具有温度、pH双重敏感性的聚(N-异丙基丙烯酰胺-co-甲基丙烯酸-β-羟乙酯)/粘土纳米复合水凝胶P(NIPA-co-HEMA/clay，并用红外和X衍射对其结构和形态进行了表征。

In addition, we have developed some sensors for phenothiazine drugs and some Chinese medicinal herbs. In last 3 years, we have published 20 SCI papers, and composed two review papers for the international journals.

另外，我们还开展了异丙嗪和氯丙嗪及马兜磷酸等药物传感器以及仿生环境中神经递质多巴胺的电化学检测等相关工作的研究，取得了一定成果。

Poly (N-isopropylacrylamide) macromonomer with a styrol end group was prepared by free radical polymerization of NIPAAm.

用链转移自由基聚合和端基置换反应，合成了聚N-异丙基丙烯酰胺热敏性大分子单体。

In the present study,a novel microgel was designed by the incorporation of temperature sensititive N-isopropylacrylamide and pH sensitive acrylic acid to copolymerize with glucosamine derivative,acrylamido-2-deoxy-glucose. The novel microgel has favorable biocompatibility,tissue-targeting and stimuli-responsibility to pH and temperature.

本文利用具有生物相容性的氨基葡萄糖单糖衍生物、具有温敏性的异丙基丙烯酰胺及具有pH敏感性的丙烯酸共聚得到了全新的微凝胶，新型微凝胶具有良好的生物相容性、组织靶向性和对温度、pH的刺激响应性。

Treatment of children with ADHD drugs more, such as methylphenidate, d-amphetamine, benzene iso-mephenytoin, caffeine, such as imipramine.

治疗小儿多动症的药物较多，如哌醋甲酯，右旋苯丙胺，苯异妥英，咖啡因，丙咪嗪等。

The surface activity and micelle behavior of the copolymers in aqueous solution were deterimned by surface tension methods.

在水溶液中，聚N-异丙基丙烯胺大分子随著温度升高会产生分子链的折叠，它的最低临界溶解温度为3236℃﹝4﹞，即在低于LCST时，它能完全溶解于水溶液中，而在LCST之上，则会产生沉淀。

Methods: Cinnarizine with domperidone, promethazine with ephedrine, dimenhydrinate plus amfetamine with ginger and phecynonate hydrochloride were chosen by reviewing journal articles. The placebo was lactose. Coriolis acceleration tolerance was used to evaluate the efficacy of drugs. The incidences of symptoms and signs, and the neurobehavioral evaluation system were used to evaluate side effects and the effect on performance respectively.

通过文献资料分析，选取脑益嗪和多潘立酮、异丙嗪和麻黄素、茶苯海明与苯丙胺和生姜联合用药，以及盐酸苯环壬脂等4组药物，以乳糖为安慰剂，用Coriolis加速度耐力评价药效，用副作用症状、体征发生率评价副作用表现，用神经行为评价系统测试副作用对工作能力的影响。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。