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Whether respiration related nuclei such as nucleus retrofacialis might play a role in the mechanism of central chemoreception on respiraton or not was also studied using the methods of local HRP application, microinjection and microiontophoresis.

采用延髓腹外侧表面敷贴HRP、微量注射酸化人工CSF及微电泳H〓的方法,探讨了呼吸相关核团NRF是否也参与延髓腹外侧表面的化学感受功能。

The largest cisterna magna measurement should be no more than 10 mm in depth and no less than 2 mm.

小脑延髓池深度最大径线应不大于10mm,且不小于2mm.18周后,在标准切面上,第四脑室不应与小脑延髓池相交通,而应由完整的小脑蚓部相分隔。

Hepcidin mRNA was expressed in the mice brain.Total RNA was extracted from choroid plexus, cerebral cortex, diencephalon and mesencephalon, cerebellum, medulla oblongata and pons in mice. RT-PCR analysis demonstrated that hepcidin mRNA was expressed in all areas of mouse brain, in choroid plexus the mRNA expression was highest, although its level is generally lower than that of liver. The PCR products were purified and verified the sequence.

小鼠脑内有hepcidin基因表达提取小鼠脑脉络丛、大脑皮层、间脑及中脑、小脑和脑桥与延髓组织总RNA进行RT-PCR表明,大脑皮层、间脑和中脑、小脑、脑桥与延髓、脉络丛均有hepcidin表达,其中以脉络丛表达较高,但与肝脏相比,表达量较低。

ERK positive cell mainly distributed at nucleus of solitary tract, ambigous nucleus, and positive fibers and cells mainly distributed at medullary visceral zone, nucleus of solitary tract and ambigus nucleus. These positive cells formed an isolated zone from nucleus of solitary tract via medullary visceral zone to SP5, which could be seen using immunohistochemical stain. Positive cells and fibers also distributed at the projection from pneumogastric nerve to the stem.

免疫组织学染色可见,阳性细胞主要分布于延髓内脏带的孤束核和疑核、阳性纤维伴随阳性细胞分布于延髓内脏带的孤束核区和疑核、呈沿孤束核经延髓内脏带至三叉神经脊束核的弧行带;在迷走神经向脑干投射部位也可见阳性胞体和纤维的分布。

After HRP application to the rostral area (n=10), quite a number of labelled cells were distributed at the ventrolateral part of the nucleus of trapezoid body, the lateroventral periolivary nucleus and the retrotrapezoid nucleus. After HRP application to the caudal area (n=10), HRP labelled cells were mainly located at the lateral reticular nucleus and the ventral part of at the lateral paragigantocellular nucleus LPGi. After HRP application to the intermediate area (n=6), only 8HRP labelled cells were observed at the in 6rats. After HRP application to the control area (n=4), only 6HRP labelled cells were found at the rostral ventrolateral reticular nucleus.

大鼠延髓腹外侧表面的头端化学感受区表面敷贴辣根过氧化物酶后,在延髓斜方体核、外周橄榄腹外侧核和斜方体后核均有HRP标记细胞存在;于尾端化学感受区表面敷贴HRP后,在延髓的巨细胞旁外侧核、外侧网状核和舌下神经核有HRP标记细胞存在;于中间区表面敷贴HRP后,在6只大鼠的延髓内部区域仅观察到8个HRP标记细胞;于对照区敷贴HRP后,在4只大鼠的延髓内部区域仅观察到6个HRP标记细胞,散在地分布在头端腹外侧网状核。

After HRP application, HRP labelled cells were distributed in the nucleus of trapezoid body , lateroventral periolivary nucleus , retrotrapezoid nucleus , lateral paragigantocellular nucleus and lateral reticular nucleus . The findings demonstrated the existence of neural structural relations between the chemosensitve areas and the Tz, LVPO, NRT, LPGi and LRt, and revealed that these nuclei might participate in the mechanism of central chemical regulation on respiration.

观察到用浸有HRP的滤纸局部敷贴于延髓腹外侧表面化学感受区后,在延髓斜方体核、外周橄榄腹外侧核、斜方体后核、巨细胞旁外侧核和外侧网状核等核团找到HRP标记的细胞,表明上述延髓内部核团与腹外侧表面化学感受区之间存在神经结构联系,提示延髓腹外侧表面化学感受区对H〓等物质的化学感受机制可能与上述核团神经元伸向该区的突起有关。

The above results indicated that the localization of NPY immunoreactive neurons in New Jianghan chicken's medulla oblongata was similar to those in broiler,silky fowl and rat, and the inferior olivary nucleus might be important position where NPY is transconducted from medulla oblongata to cerebellum.

表明,江汉鸡延髓NPY阳性神经元的分布与肉鸡、乌鸡、大鼠的大体相似;下橄榄核可能是NPY在延髓-小脑传递通路中的一个重要枢纽。神经肽Y;SABC法;延髓;江汉鸡

Of the 26 lesions with pontine and bulbar involvement, three had no association with other lesions (Fig 2). Twelve were associated with tegmental and superior cerebellar peduncular extension, and six showed corticospinal tract involvement in continuity with an MDJ lesion. In one patient with additional telencephalic lesions, the right side of the pons was hyperintense on long TR/TE images that did not cross the midline, suggestive of an arterial lesion (Fig 3). In two patients with pontine tegmental lesions, there was an associated middle cerebellar peduncle and deep cerebellar white matter involvement (Fig 4). Two others had associated cervical lesions.

在26处脑桥延髓区病灶中,3处病灶仅限于脑桥延髓区,其它部位无病灶(图2);12处病灶还同时伴有背盖部和小脑上脚/结合臂处病灶;6处病灶为与中脑-间脑接合处病灶相连的皮质脊髓束受累;还有1例患者除端脑见病灶外,右侧脑桥于T2像也见高信号病灶,但未超越正中线,提示可能系动脉病变所致(图3);2例脑桥背盖部病灶的患者同时伴有小脑中脚/小脑脑桥脚和小脑深部白质受累(图4);还有2处脑桥延髓区病灶还同时伴有颈髓病灶。

Increased expression of PENK mRNA was more marked in the ipsilateral dorsal horn of the spinal cord, especially in lamina Ⅲ-Ⅳ and the contralateral medulla, especially in the gigantocellular reticular nucleus, lateral paragigantocellar reticular nucleus and lateral reticular nucleus.

本实验用原位杂交技术对电针刺激后前脑啡肽mRNA在脊髓和延髓的表达进行了观察,发现给予大鼠单侧后肢电针刺激引起脊髓和延髓中PENK mRNA阳性神经元数显著增加,尤其是同侧脊髓背角各层PENK mRNA的表达,和对侧延髓网状结构如网状巨细胞核α部、网状巨细胞外侧旁核及外侧网状核中的PENK mRNA表达增加,这与脊髓上传的信号由同侧脊髓交叉到对侧脑干的走行方式是一致的。

Results There was an extensive staining with both P2X2 and P2X4 receptors positive neurons and nerve fibers localized in medulla oblongata. It was mainly localization in the nucleus tractus solitarius,Ⅻ nucleus and ventrolateral medulla of medulla oblongata. It also scattered throughout rest of medulla.

结果 P2X2和P2X4嘌呤受体的阳性神经元和阳性纤维在新生鼠和成年鼠的延髓都有广泛表达,主要分布在孤束核、Ⅻ颅神经核和延髓腹外侧区,延髓其他区域为散在的分布。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。