延长

The Ⅰ-Ⅴ interval and interaural latency difference of Meniere's syndrome patients were within normal limits. Therefore, the abnormality of hearing is mainly in the cochlea and th...

波延长者40％，其中多数伴有Ⅰ波亦延长，但Ⅰ—Ⅴ波间期均不延长，ILD亦不延长，后两项指标应为与脑干占位疾病鉴别的主要依据。

Results:①The amount of human colon carcinoma cell line SW480 treated by quercetin decreased. The morphology of partial SW480 cells was shrunk volume, integrated cell membrane, condensed cytoplasm, pyknotic chromatin, nuclear fragmentation. Apoptotic Corpuscles were found by electron microscope.②MTT colorimetric assay showed quercetin inhibited the growth of human colon carcinoma cell line SW480 in a time- and dose-dependent manner when the concentration of quercetin was 30、60、90μmol/L.③Flow cytometry analysis showed the cell cycle of SW480 cell was restricted in G1/S. G0/G1 phase rate increased and S phase rate decreased with increasing concentration of quercetin and time lasting.④ Zymogram analysis assay showed the secretion of matrix metalloproteinases in human colon carcinoma cell line SW480 treated by quercetin decreased. With increasing concentration of quercetin, the secretion of MMP-2 and MMP-9 decreased.⑤Immunohistochemistry method demonstrated the position expression of Cathepsin-D in SW480 cell was suppressed by quercetin in a time- and dose-dependent manner.

研究结果：经槲皮素处理的人结肠癌SW480细胞数量减少，部分细胞体积缩小，细胞膜完整，胞浆浓缩，核染色质固缩，细胞核碎裂，形成凋亡小体；MTT法检测显示当作用浓度为30μmol/L~90μmol/L时，槲皮素对人结肠癌SW480细胞的生长有抑制作用，其抑制作用随着作用浓度的增加和作用时间的延长而增强；流式细胞学发现槲皮素主要作用于人结肠癌SW480细胞周期的G1/S期，大部分细胞被阻断于S期，随药物浓度的升高和作用时间的延长，G0/G1期细胞比例逐渐增加，S期细胞比例逐渐减少；酶谱分析法检测显示不同浓度的槲皮素能够抑制人结肠癌SW480细胞分泌MMP-2及MMP-9，随浓度的升高，MMP-2及MMP-9的分泌量减少；免疫组织化学法显示不同浓度的槲皮素处理人结肠癌SW480细胞后，Cathepsin-D的表达随药物浓度的升高和作用时间的延长而降低。

Methods 39cases were selected as research group that were given prolongation-delamination anastomosis. The esophagogastric mucous membrane was lengthed by2cm and3cm.Esophagogastric mucous membrane and seromuscular were separately anastomosed layer by layer.

选择3年来39例行食管胃黏膜延长分层吻合的病人为研究组，这些病人食管黏膜延长2cm，胃黏膜延长3cm，并分别吻合黏膜层和肌层。

Methods: Model of limb lengthening was established by upper metaphyseal osteotomy and fixed with a half-ring sulcated external fixator on rabbit tibia. Rate of distraction was 1mm per day (0.5mm each time).

以兔胫骨上干骺端截骨缓慢牵伸延长为动物实验模型，延长速度：1mm／d，分2次完成，延长幅度为原胫骨长度的10％、20％及40％三种。

In order to study the mechanism of the inhibitory effect of salvia miltiorrhiza and tetramethyl pyrazine on scar fibroblast, the DNA content of fibroblast and the all distribution in cellular cycle was measured by FCM. The hypertrophic scar tissue of chest was chosen for primary culture of fibroblast.

摘 要 应用流式细胞光度分析法测定丹参和川芎嗪对体外培养的瘢痕成纤维细胞DNA相对含量和细胞周期时相变化，发现药物在一定浓度作用下，DNA指数无明显变化；丹参使C2-M期细胞分布增多，G2-M期延长；川芎嗪使G2-M期细胞分布增多，G2-M期、S期延长；药物使细胞群体倍增时间延长，与浓度呈明显直线正相关。

The conclusions were that the inhibitory effect of SM was the result of inhibiting the mitosis of cells and the cellular cycle be at a standstill in G2-M stage.

应用流式细胞光度分析法测定丹参和川芎嗪对体外培养的瘢痕成纤维细胞DNA相对含量和细胞周期时相变化，发现药物在一定浓度作用下，DNA指数无明显变化；丹参使C2-M期细胞分布增多，C2-M期延长；川芎嗪使C2-M期细胞分布增多，C2-M期、S期延长；药物使细胞群体倍增时间延长，与浓度呈明显直线正相关。

METHODS Mice hot-plate, writhing test and mice menalgia model of acute stress blood stasis rat was used to compare therapeutic action of the three preparations RESULTS Both chuanxiong formula granule and decoction pieces standard broth of liquored Chuanxiong formula granule and decoction pieces stand ard broth could prolong pain threshold, extend incubation period caused by acetic acid andoxytocin, reduce writhing frequency, and improve some indexes of hemoreology in acute stress blood stasis rat.

选择热板法、扭体法、痛经模型、急性应激血淤血液流变性等方法，比较川芎配方颗粒及饮片、酒川芎配方颗粒及饮片的主要药理作用。结果川芎配方颗粒与川芎饮片标准汤剂、酒川芎配方颗粒与酒川芎饮片标准汤剂均能延长小鼠热板痛闭值，均能延长醋酸所致扭体反应的小鼠扭体潜伏期并减少扭体次数，均能延长小鼠痛经模型中催产素所致扭体反应的潜伏期并减少扭体次数，均具有改善急性应激血淤大鼠血液流变的作用。

Results: After three experiments, more than 50% average life-prolonging rate were found in both HuLuZhuan and ShuangGouZhuang groups of high and low doses, the high dose ShangShanHu group and the MengLaoHu and XiaoHongZhuan groups of low dose for the rats with tumor S...

结果：经3次实验，在生命延长率方面：对S180腹水瘤小鼠平均生命延长率超过50%的有葫芦钻、双钩钻高低剂量组，上山虎高剂量组和猛老虎、小红钻低剂量组；对H22腹水瘤小鼠平均生命延长率超过50%的有六方钻和双钩钻高剂量组。

The results showed that GP (320 mg/kg) combined with ADM (2 mg/kg) could significantly prolong survival Lime of mice bearing SF763 tumor, the life-prolonging rate was 88%(P40 mg/kg) significantly had a inhibition no A549 (P.05), the optium dosage of GP was 80 mg/kg, which had an inhibition of 82.2%(P.01) after an inoculation of 11 days; GP had a negative relation on prolonging survival time of mice bearing EC tumors between dosage of GP and the effect. The optimum dosage was 5-10 mg/kg, which had optimum prolonging rate of 32.77%(P.05). Thus GP could significantly prolong survival time of mice bearing SF763, A549 and EC tumors.

结果表明：生药剂量320 mg/kg GP联合2 mg/kg阿霉素，其生命延长率为88%(P01)，GP能明显延长荷人脑瘤SF763裸鼠生命；GP在大于40 mg/kg时对人肺腺瘤A549裸鼠具有明显的抑制作用(P.05)，最佳剂量为GP 80 mg/kg，接种时间11d，抑瘤率为82.2%(P.01)；GP对艾氏腹水瘤EC小鼠的生存期呈现负量效关系，GP最佳剂量范围在5~10 mg/kg，最高生命延长率为32.77%(P.05)。

Results The experimental eyes quickly changed from pre-experimental hypermetropin to high myopia during the experimental period, and the severity of myopia and axial length increased relative to the period of form deprivation. The expression of VIPR2 mRNA and the levels decreased over time for both groups.

结果 实验组由实验前远视眼快速演变为高度近视眼，并随遮盖时间的延长、近视度数的加深，眼轴延长；两组眼球后壁均有VIPB2 mRNA的阳性表达；随着出生时间的延长，两组VIPR2 mRNA的表达均逐渐下降。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。