应用层

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要：成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

In this paper, a new method has put forward in optical tomography and a new application put forward in spectroscopic analysis.

本文提出了光声技术在层析成像方面新的实现方法及在光谱分析领域中新的应用。

Mutti-slice helical CT VR and MPR reconstruction have an important value in thoracic injury's diagnosis and clinical application. We can observe these injuries stereoscopically.

多层螺旋CT VR和MPR在胸部损伤中有重要的诊断和临床应用价值，能够空间立体地观察胸部损伤情况。

This paper introduces the mathematical basis of multi-trace coherency techniqu e. Real data test shows that the 3-D coherency technique can determine the faul t plane extent and its detailed features quickly and accurately, and the stratal occurrency information provided by t...

本文介绍了多道相关技术的数学原理，实际应用证明，三维相干技术不仅可以快速、准确地确定断层的平面展布及其细节特征，而且可以利用其提供的地层产状信息研究目标储层的构造沉积演化体系。

This method has been applied to fluvial reservoirs of lower Minghuazhen Formation of Gangdong oil field, including setting high resolution isochronal stratigraphic framework on the base of intermediate term stratal cycle and predicting the location and type of sand bodies based on their size derived.

应用该方法对比黄骅坳陷港东油田明化镇组下段部分河流相储集层，首先建立以中期地层旋回为基础的等时地层格架，再以微相类型相同为对比约束条件，然后根据确定的砂体大小预测出砂体的位置和类型。

Eighteen compounds have been isolated from the lipid friction of the sponge suberites tylobtusa levi.

摘 要 采用体外细胞毒活性追踪的方法，应用多种层析手段，从采自西沙群岛永兴岛的皮海绵脂溶性部分中分离得到十八个化合物。

Thus sulphamate electroplating technology was used to prepare nickel coating for the repair of the airplane parts.

氨基磺酸盐电镀镍工艺镀层内应力小、沉积速度快，且具有较好的结合力，可以很好地应用于飞机零件维修。

Methods:One hundred and twenty－nine cases of supraglottic laryngeal carcinoma were retrospectively analysed through testing nm23－H1 and laminin expression by immunohistochemical staining.

应用免疫组化染色检测nm23－H1基因和层粘连蛋白的表达，回顾性分析129例声门上喉癌的病例资料。

With the rapid development of tall buildings, frame-tube structure swith a strengthened layer have been in more and more use in practicalengineering.

随着高层建筑的迅猛发展，带加强层框架-核心筒结构体系在实际工程中得到了越来越多的应用。

The mechanism of additional effect is very complicated. Experiment indicated that the additional effect of shallow water-accumulating gob had significant impact on transient electromagnetic signals. And the additional effect could not be simply incorporated into disturbance. The cause of additional effect was analyzed theorically. The examples confirmed that a the application of additional effect in detection of water-accumulating gob can produce ideal results.

附加效应产生的机理很复杂，试验表明，浅层的积水采空区的附加效应对瞬变电磁信号的影响很大，不能将这种现象简单的归结为干扰，本文从理论上分析了附加效应产生的原因，实例证明将附加效应应用到积水采空区的探测中能取得理想的效果。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。