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For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此,本文以难溶性的格列齐特为模型药物,在传统型推拉式渗透泵的基础上,设计并制备了双面打孔型推拉式渗透泵;通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面,对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察,同时,应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究;在此基础上,通过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定,结合流体力学中的Poiseuille层流定律方程,对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

Traditional Web application can be divided into three tiers: presentation tier, business logic tier and data tier.

传统的Web应用大致可以分为简单的三层:表示层,业务层和数据层。

Guided with the theory of high resolution sequence stratigraphy and based on previous research results,we constructed sequence stratigraphic scheme of Qingshankou Formation which was in front zone of the west slope in southern Songliao Basin,where six sequence boundary surfaces were identified and 5 mediumterm baselevel cycleswere divided.

在前人研究的基础上,应用高分辨层序地层学理论与研究方法,对松辽盆地南部西斜坡地区的青山口组地层进行了层序地层划分与对比工作,从中识别出6个具等时意义的层序界面,将其划分为5个中期基准面旋回(4级层序)。

Performed tests based on seven kinds of important structural parameters which were wall thickness, shielding thickness, the radial wall shielding insertion depth, the width of the radial electrode, the electrode width, the relative dielectric constant of wall material and filler shield relative dielectric constant, and studied on structural parameters and the corresponding performances by RBF neural network, the optimization based on PSO was performed with the regression model.

该方法以敏感场整体灵敏度大小等系统性能为优化目标,基于管壁厚度、屏蔽层厚度、径向屏蔽插入管壁深度、径向电极宽度、电极宽度、管壁材料的相对介电常数、屏蔽层填充物相对介电常数7种重要的结构参数进行试验。应用RBF神经网络对多组结构参数以及对应的系统性能指标进行学习,得到回归模型,并应用粒子群算法进行寻优。

Based on these parameters,cross plot technique and mathematical statistics analysis are used to establish norms and methods for effectively and visually identifying shallow gas zone.

并在此基础上,应用交会技术和数理统计方法建立了有效地快速直观显示浅气层的标准和方法,为应用老井资料识别浅气层提供了科学依据。

The study provided 2 kinds of finish systems which were pouring and anchoring rock-wool panel respectively. In general, galvanizing steel-meshwork using machine anchor can use all kinds of Rock-wool panel made in China. The interface mortar used in Rock-wool can prevent worker's hand from hurting and improve the water-proof capability and bonding intensity of rock-wool panel. The low-heat conductivity of polystyrene foaming granule paste improved the integer and anti-crack of system. The 2 kinds of rock-wool system all can resolve the current rock-wool panel applied difficulty in outer-wall external thermal insulation.

研究提出了现浇和锚固岩棉板2种涂料饰面构造做法,其中采用机械锚固热镀锌钢网施工可充分利用国产各类型岩棉板;岩棉板的界面砂浆处理可起到防止岩棉纤维扎手、增强岩棉板的防水性能和提高岩棉板与找平层的粘结强度的作用;聚苯颗粒的低导热系数过渡层提高了系统的整体性和抗裂性。2种构造做法经试验和工程试点证明均可解决目前国内岩棉难以应用在外墙外保温系统中的技术问题,具有优异防火性能的岩棉外保温系统可应用于任何类型的建筑中,在高层建筑和防火要求高的建筑中其优势更为明显。

The study provided 2 kinds of finish systems which were pouring and anchoring rock-wool panel respectively. In general, galvanizing steel-meshwork using machine anchor can use all kinds of Rock-wool panel made in China. The interface mortar used in Rock-wool can prevent worker's hand from hurting and improve the water-proof capability and bonding intensity of rock-wool panel. The low-heat conductivity of polystyrene foaming granule paste improved the integer and anti-crack of system. The 2 kinds of rock-wool system all can resolve the current rock-wool panel applied difficulty in outer-wall external thermal insulation. The rock-wool external thermal insulation which has very nice fire-proof capability can apply any kinds of builds, especially high-rise buildings.

研究提出了现浇和锚固岩棉板2种涂料饰面构造做法,其中采用机械锚固热镀锌钢网施工可充分利用国产各类型岩棉板;岩棉板的界面砂浆处理可起到防止岩棉纤维扎手、增强岩棉板的防水性能和提高岩棉板与找平层的粘结强度的作用;聚苯颗粒的低导热系数过渡层提高了系统的整体性和抗裂性。2种构造做法经试验和工程试点证明均可解决目前国内岩棉难以应用在外墙外保温系统中的技术问题,具有优异防火性能的岩棉外保温系统可应用于任何类型的建筑中,在高层建筑和防火要求高的建筑中其优势更为明显。

So from the aspects of economical and social benefit, it has a lot of advantages. On the other hand CFG pile with long screwy drill pipe inner pump pressure is low noisy and without muddy water pollution; The process of drilling will not lead to vibration and has the capacity to penetrate hard rock layer; Also the construction is of high efficiency.

并且长螺旋钻管内泵压成桩工艺具有低噪音,无泥浆污染;成孔制桩时不产生振动;成孔穿透能力强,可穿透硬土层,诸如沙层、圆砾层和粒径不大于60mm的卵石层;施工效率高等优点,所以该技术在全国推广后,得到了广泛的应用,目前已成为应用较为普遍的地基处理技术。

In order to enlarge applied field of autoclaved aerated concrete block, China engineering building standardization association sent down "A class Autoclaved aerated concrete block and brickwork structure technology rules". The rules point out definitely building autoclaved aerated concrete block tier building can only use A class Autoclaved aerated concrete block.

为了将蒸压加气混凝土砌块推广应用至具有节能、抗震保障的多层承重建筑,扩大应用领域,以求得加气混凝土行业的更大发展,中国工程建设标准化协会砌体结构委员会已下达了,《A类蒸压加气混凝土砌块砌体结构技术规程》,规程将明确指出建造加气混凝土砌块多层房屋只能用A类蒸压加气混凝土砌块。

The up-to-date call center include many kinds of advanced technologies: telephone switch、computer tech、CTI and IN.

传统的呼叫中心数据库设计采用的是二层结构,随着企业应用系统的不断扩充和新应用的不断增加,二层数据处理结构暴露出许多问题。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

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