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The expression absence of LRRC4 was ascribed to the loss of homozygosity of 7q32-ter in U251 cell lines. Conclusion The expression of LRRC4 gene is absent in glioblastoma cell lines, and it offers the important experiment proof for LRRC4 to act as a new candidate of brain tumor suppressor gene from glioma.

通过对胶质瘤细胞系基因组DNA中LRRC4的ORF序列的PCR扩增和测序分析,发现SF126,SF767,M17细胞中,ORF序列第279位氨基酸的第3个密码子存在同义点突变(3/5),而U251和U87细胞基因组DNA中发生了LRRC4基因的缺失突变(2/5)。

Methods. This prospective study included 152 consecutive patients, sequentially divided into 2 groups, underwent Windows technique and decompressive laminectomy group by 2 groups of surgeons.

这个前瞻性研究包括152位序贯患者,随后被分成2组,两组医生分别完成开窗减压和减压性椎板切除术。

The time's expression form and its connotation in steel manufacturing route have been analyzed.Some concepts,such as time point,time sequence,time domain,time position and time rhythm have been put forward.

对时间在流程中的表现形式及其内涵进行了系统解析,提出了时间点、时间序、时间域、时间位和时间节奏等概念及其内涵。

Magnetization measurements indicate that the Neel temperature for the Pr sublattice is 19.0K, which is 2K higher than the previously reported va...

磁测量显示Pr的反铁磁序温度为 19.0K ,比前人报导值高出 2K ,进一步证实样品中仅含有很少的Pr占据Ba位的缺陷。

The second type of motif,the zinc finger,consists of a peptide loop with either two cysteines and two histidines or four cysteines at the base of the loop that tetrahedrally co-ordinate a zinc ion.

另一种基序称为锌指,由一个肽环构成,在肽环底部是两个半胱氨酸和两个组氨酸或四个半胱氨酸,与锌离子配位形成面体。

It is revealed that in the condensates, the different configurations of order parameters lead to different topological structures-velocity field vortex lines, Mermin-Ho vortex lines and monopoles, and these three topological structures can all be characterized by the Hopf indices and Brouwer degrees of φ-mapping, and their locations and motions also be rigorously determined by φ-mapping theory.

文中指出,在凝聚体中,序参量的不同位形导致了不同的拓扑结构—速度场涡旋线、Mermin-Ho涡旋线和单极,而这三种结构都可由Φ-映射Hopf指标和Brouwer度所表征,并且它们的位置和运动亦可由Φ-映射理论严格确定。

It is considered that influenced by the strike-slip movement of Tanlu Faults and "episodic" chasmic evolution, buried hill draping structures with different sequences are created from the north to south in Kandong-Zhuanghai buried hill draping structure.

认为受郯庐断裂带走滑运动和渤海湾盆地第三纪&幕式&裂陷演化的影响,垦东-桩海潜山披覆构造带自北向南形成不同位序的潜山披覆构造。

This paper analyses the characteristics of urban system in Anhui Province. It is found that this region exhibits a city-size distribution following the rank-size rule. The urban primacy index is low, the scale effect is inevident, the urban scale is small in whole, the development of metropolis and big cites is not enough, medium-sized cities is prominent and the spatial distribution of cities is not equal.

运用统计数据,在深入分析的基础上,发现安徽省现状城市体系的等级规模结构呈位序—规模分布;城市首位度偏低,规模效应不明显;城市规模总体偏小,特大城市和大城市发育不足,中等城市突出;城市规模空间分布不均衡,区域分异明显。

It is found that this region exhibits a city-size distribution following the rank-size rule. The urban primacy index is low, the scale effect is inevident, the urban scale is small in whole, the development of metropolis and big cites is not enough, medium-sized cities is prominent and the spatial distribution of cities is not equal.

运用统计数据,在深入分析的基础上,发现安徽省现状城市体系的等级规模结构呈位序-规模分布;城市首位度偏低,规模效应不明显;城市规模总体偏小,特大城市和大城市发育不足,中等城市突出;城市规模空间分布不均衡,区域分异明显。

Methods: According to the mechanism of cough reflex, the c-fibres's role in the respiratory system, and the principle of isosterism. Here, a peripheral antitussive LD was regarded as a lead compound. Amino functional groups, as substituents at the 1-hydroxy group of the racemate of LD, were introduced into the structure of the molecule. These novel compounds were confirmed by 1H-NMR, MS spectrum. Their antitussive activities were studied on mice in sequential method. The EDT50, the stimulating time that caused cough by NH3 on half of mice, were measured. Then could caculated the ratio R between the EDT50 of the treated groups and control group.

根据咳嗽反射的机制及C-纤维在呼吸系统的作用,以外周镇咳药左羟丙哌嗪为先导化合物,依据电子等排原理,在其结构中引入氨基以取代羟丙哌嗪分子中1位的羟基,设计一系列未见报道的化合物(01-15);并采用了一条适宜的路线进行合成,通过1H-NMR、MS确证结构;采用&序贯法&实验进行新化合物的镇咳活性研究,动物模型采用氨水引咳小鼠,获得引致半数小鼠咳嗽的氨水刺激时间(EDT50)及给药组EDT50与对照组的比值R。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力