帕尔马斯

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

Parma boss Stefano Pioli was still looking for his first Serie A victory with just one point to his name so far and was missing Massimo Paci, sitting out a two-match ban for having simulated an elbow from Luca Toni, and the injured Andrea Gasbarroni and Zlatan Muslimovic.

帕尔马的主教练 Stefano Pioli 也同样非常渴望取得他执教意甲联赛的第一场胜利，之前的三轮联赛他只取得了一个积分，这与他的期望相差很远。但是帕辛因为在上一轮的比赛中肘击托尼而遭到了两场联赛禁赛的惩罚而缺席这场比赛，另外，加斯巴罗尼和穆斯里莫维奇也都因伤缺阵。

It occasioned my being more considered by Mr. Palmer as a young man of some ingenuity, though he seriously expostulated with me upon the principles of my pamphlet, which to him appeared abominable.

n， w+ N+ u$|8 S' F% p 突然我的作品为帕尔马斯先生发现，虽然他严重抗议我这本小册子的主张，据他看来是非常厌恶的，然而却因一个年轻人有这样的聪明而多加注意。

R d; '+?$ z# v2 {5 U'}* I It occasioned my being more considered by Mr. Palmer as a young man of some ingenuity, though he seriously expostulated with me upon the principles of my pamphlet, which to him appeared abominable.

v8 b8 o$ j 4 a a 突然我的作品为帕尔马斯先生发现，虽然他严重抗议我这本小册子的主张，据他看来是非常厌恶的，然而却因一个年轻人有这样的聪明而多加注意。

Journal of Agricultural and Food Chemistry Effect of Different Cooking Methods on Color, Phytochemical Concentration, and Antioxidant Capacity of Raw and Frozen Brassica Vegetables Abstract Full Text HTML Hi-Res PDF[965 KB] PDF w/ Links[892 KB] Nicoletta Pellegrini*, Emma Chiavaro, Claudio Gardana§, Teresa Mazzeo, Daniele Contino§, Monica Gallo#, Patrizia Riso§, Vincenzo Fogliano# and Marisa Porrini§ Department of Public Health, University of Parma, via Volturno 39, 43125 Parma, Italy Department of Industrial Engineering, University of Parma, viale GP Usberti 181/A, 43124 Parma, Italy § Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, sezione Nutrizione Umana Universit degli Studi di Milano, via Celoria 2, 20133 Milan, Italy # Department of Food Science, University of Napoli "Federico II", Parco Gussone, 80055 Portici, Napoli, Italy J.

农业化学与食品化学杂志对不同烹饪方法对颜色，植物化学浓度，及抗氧化能力的原料和冷冻甘蓝菜抽象全文网页高清晰度PDF格式[965 KB的] PDF格式瓦特/友情链接[892 KB的] 妮可佩莱格里尼*，艾玛基亚瓦罗，克劳迪奥加尔达纳§，特雷莎Mazzeo，丹尼尔蒂诺§，莫妮卡加洛＃，帕特里齐亚公共卫生部，帕尔马大学，通过沃尔彻诺39，43125帕尔马，意大利工业工程，帕尔马是：Viale大奖赛乌斯贝蒂大学181 /年，43124帕尔马，意大利§ Dipartimento迪有关科学é Tecnologie Alimentari é Microbiologiche，sezione Nutrizione乌马纳大学德利阿布鲁史都迪迪米兰，通过西洛里亚2，20133米兰，意大利＃食品科学系，那不勒斯&费德里科二&大学，Parco公司古索，80055波尔蒂奇，那不勒斯，意大利 j的农耕。

Spanair Flight 5022 was packed with vacationers bound for Las Palmas in the Canary Islands, normally a three-hour flight.

西班牙航班5022上拥挤着飞往位于金丝雀岛屿的拉斯帕尔马斯的度假客，常规飞行三小时即达。

Spanair Flight 5022 was packed with vacationers bound for Las Palmas in the Canary Islands, normally a three-hour flight.

西航5022班机搭乘去往位于CANARY群岛的拉斯帕尔马斯的游客，航程约3个小时。

Spanair Flight 5022 was packed with vacationers bound for Las Palmas in the Canary Islands, normally a three-hour flight. After a 90-minute delay, the MD-82 single-aisle aircraft, with 172 passengers and crew, tried to take off about

西班牙航班5022满载去往加利那岛的拉斯帕尔马斯旅游的乘客，通常是3小时的航程。90分钟的延误以后，MD-82单通道飞机载着172名旅客和机组人员试着在下午2点45分起飞。

The 2007 Lyra Imaging Symposium Celebrates 10 Years of Insight and Leadership Earlybird Registrants Save 24150 - t the Rancho Las Palmas Resort and Spa in Rancho Mirage California To celebrate the event%26%23039%3Bs tenth anniversary the Symposium%26%23039%3Bs official theme is %26quot%3BLeading the Way: 10 Years of Imaging Industry Insight%26quot%3B To save $150 off ...

2007lyra成像研讨会庆祝十年洞察力和领导earlybird登记节省24150-笔地区Rancho拉斯帕尔马斯加州幻象牧场度假、温泉庆祝活动26%23039%3BS中十周年座谈会26%23039%3BS中正式主题是百分之零3bleading26quot方式：10年影像业界有识之士26quot百分之零三号乙拯救过：：150

Major Cities: Madrid, Barcelona, Valencia, Sevilla, Zaragoza, Malaga, Bilbao, Las Palmas, Valladolid.

主要城市：马德里，巴塞罗纳，巴伦西亚，塞维利亚，萨拉戈萨，马拉加，毕尔巴鄂，拉斯帕尔马斯，巴利阿多利德。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。