巴比妥钠

MethodsThe pharmacological effects of the Ziziphus jujube leaf extract on the autonomic activities of mice, the time of sleep induced by pentobarbital sodium, the sleeping synergistic action of mice with barbital sodium at sub-threshold and hypnotic dosages and the central inhibitory effects in mice induced by amphetamine were investigated.

方法考察酸枣叶提取物对小鼠自主活动的影响、对延长戊巴比妥钠诱导的小鼠睡眠时间、对阈下巴比妥钠的睡眠协同作用以及对苯丙胺中枢兴奋作用的影响。

Nembutal Sodium exerts a depressant action on the CNS and shares the sedative-hypnotic actions typical of the barbiturates.

戊巴比妥钠对中枢神经系统产生抑制作用，并显示戊巴比妥类特有的镇静催眠作用。

Methods:Phenobarbital and Valproic acid were added into astrocytes and cultured permanently for 30 days. P-glycoprotein, a product of MDR1, was detected with immunocyto chemistry. Then, 5μg/ml Sibelium was added to resistance cells and nonresistance cells, MTT assay was used to measure reverse multiple and relative reverse efficiency rate.

将苯巴比妥钠和丙戊酸钠分别加入培养的星形胶质细胞内，30天后用免疫细胞化学法检测MDR1的表达产物P-糖蛋白，继之将终浓度为5μg/ml的西比灵分别加入培养的正常细胞及MDR1表达增强的细胞内，用四甲基偶氮唑盐法计算逆转倍数和相对逆转效率，了解西比灵逆转MDR1表达的作用。

Objective To establish an animal model of refractory epilepsy by peritoneal injection of phenytoin sodium and phenobarbital sodium, and investigate into their multidrug resistance mechanism in kindling rats.

目的 探索性应用苯妥英钠、苯巴比妥钠诱导建立难治性癫疒间动物模型，并研究其多药耐药机制。

AIM: To observe the effect of pentoxifyllinel on inhibition of respiration induced by acute poisoning with pentobarbital sodium , and to study the mechanisms for action of pentoxifyllinel on antagonizing the central inhibition of respiration resulted from the barbitalism.

目的： 观察己酮可可碱对急性戊巴比妥钠药物中毒所致呼吸抑制的影响，探讨其在解救巴比妥类药物中毒所致中枢性呼吸抑制中的作用及机制。

In groups B1, B2 and B3 , after 10 minutes of injecting the additional dose of pentobarbital sodium, pentoxifyllinel in doses of 60mg/kg, 30mg/kg and 15mg/kg were injected respectively. In group C, 125mg/kg of nikethamide was injected after 10 minutes of injecting the additional dose of pentobarbital sodium.

在B1、B2、B3 三组家兔，于再注戊巴比妥钠后(即加注15 mg/kg戊巴比妥钠后)10 分钟，按等比级数分别注射60mg/kg、30mg/kg、15mg/kg 剂量的己酮可可碱；在C 组家兔则注射尼可刹米125 mg/kg 作阳性对照药物。

In comparison with the control group, the time to falling asleep and the duration of sleep due to supraliminal dosage of sodium pentobarbital were shortened and prolonged significantly, respectively,in the small-dosage and large-dosage groups.

橙皮水提取物小剂量给药组，大剂量给药组能显著加速阈上剂量戊巴比妥钠的入睡时间和延长戊巴比妥钠的睡眠时间，差异有显著性意义。

Methods After taking triazolam and distilled water respectively, the mice sleeping-behavior state was observed and recorded; the ratio of sleeping mice was recorded after taking different of ingredients Eucommia ulmoides Oliv. combining with pentobarbital sodium at subliminal dose, and mice latent period and sleeping time at supraliminal dose. Measure the content of interleukin-1β(IL-1β) in mice brain with enzyme-linked immunosorbent assay, weigh spleen and thymus of mice.

通过观察记录日间小鼠睡眠行为状态，戊巴比妥钠阈下催眠剂量实验，延长戊巴比妥钠睡眠时间实验，酶联免疫吸附反应分别检测服用3种不同极性的提取部位、阳性对照物和空白对照组的小鼠脑组织中IL-1β含量，并结合脏器指数等综合分析。

MethodsThe pharmacological effects of the Ziziphus jujube leaf extract on the autonomic activities of mice, the time of sleep induced by pentobarbital sodium, the sleeping synergistic action of mice with barbital sodium at sub-threshold and hypnotic dosages and the central inhibitory effects in mice induced by amphetamine were investigated.

目的观察酸枣叶提取物对中枢神经系统作用。方法考察酸枣叶提取物对小鼠自主活动的影响、对延长戊巴比妥钠诱导的小鼠睡眠时间、对阈下巴比妥钠的睡眠协同作用以及对苯丙胺中枢兴奋作用的影响。

The electrical activity of Ⅻ nerve rootlets and inspiratory neurons were recorded.

在改良Krebs液中分别单独加入巴比妥类药物苯巴比妥钠，终浓度分别为20、40、60、80μmol/L，持续灌流1h，观察舌下神经根RRDA及吸气神经元单位电活动的变化。

Shop assistant: Please check at the door.

店员：请您到门口柜台交费。

In the end, transportation of PAHs in the environmental matrix was preliminarily investigated and discussed according to PAHs data of soils and sediments from a certain region in Shanghai. The result indicated that there are two or more pathways on PAHs transportation in the environmental matrix.

最后，对上海特定地区内PAHs在环境介质中的迁移径途进行了分析讨论，结果表明上海市土壤和沉积物等环境介质中PAHs的迁移存在多种途径。