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Objective To investigate the photodynamic therapy of human erythroleukemia cell line K562 and drug-resistance cell line K562/ADM using hexyl 5-aminolevulinate is vitro.

目的 探讨5-氨基乙酰丙酸己酯-光动力疗法对人红白血病细胞株K562及其耐阿霉素细胞株K562/ADM的杀伤效应。

And then the title compound was synthesized through reacting of 5-fluorouracil with hexyl isocyanate in the presence of 4-(N,N-diethylamino)pyridine as catalyst.

以正庚酸、氯化亚砜和叠氮化钠为原料,通过酰化、库尔提斯重排反应制备异氰酸己酯,然后在4吡啶催化下与5氟尿嘧啶缩合得到抗癌药物卡莫氟,总收率75.4%。

The most commonly used drugs Bleomycin, mitomycin C, Adriamycin, 5 - 5-fluorouracil (5 - Fu), methotrexate, cyclohexyl - nitrosourea, imipramine hydrazone, Vindesine, etoposide (VP-16), chlorine and ammonia-platinum, a single chemotherapy drug remission rate in the 15% to 20% remission for 1 to 4 months.

最常用的药物有博来霉素、丝裂霉素C、阿霉素、5-氟尿嘧啶(5-Fu)、甲氨喋呤、环己亚硝脲、丙咪腙、长春花碱酰胺、鬼臼乙叉甙(VP-16),以及顺氯氨铂,单一药物化疗的缓解率在15%~20%,缓解期为1~4个月。

The bioluminescence inhibition of N-hexylpyridinium b is imide and dichlorvos to Vibrio-qinghaiensis sp.-Q67 was determined by the microplate toxicity analysis.

应用微板毒性分析法,首先测定了离子液体N-己基吡啶双酰亚胺与敌敌畏对青海弧菌Vibrio-qinghaiensis sp。

Objective: To explore the effects of 1-4 -[2 -( 1- ethyl - 2,3 – dioxopiperazine-4- carboxamido ethyl] -phenylsulfonyl -3 -cyclohexyl urea on the fasting blood glucose and the blood lipemia in the streptozotocin -induced diabetic once and the glucose uptake in SMMC7721 cells.

目的:研究观察二氧代哌嗪苯磺酰环己脉对链脲佐菌素诱导的2型糖尿病小鼠血糖血脂的影响以及刺激SMMC7721细胞对3H-2-脱氧葡萄糖吸收影响。

N-formyl morpholine was synthesized using morpholine and formic acid as starting materials,phosphorous acid as catalyst and cyclohexane as water carrying agent.

以吗啉和甲酸为原料,磷酸为催化剂,环己烷为带水剂合成了N-甲酰吗啉。

The surface hydroxyl group onto magnetic polyvinyl acetate nanoparticles can be obtained by saponification reaction on their surface.

结果表明,磁性聚苯乙烯颗粒与丁二酸酐发生Freidel-Crafts酰基化反应,可以在颗粒表面引入少量羧基;磁性聚甲基丙烯酸甲酯颗粒分别与乙二醇、二缩三乙二醇、聚乙二醇等发生醇-酯交换反应,可以在颗粒表面接枝不同分子链长度的末端羟基;磁性聚醋酸乙烯酯颗粒经过醇解或皂化反应可以获得表面羟基;磁性聚丙烯酸甲酯颗粒通过乙二胺或1,6己二胺的胺解反应可以得到表面氨基,继而与一氯乙酸反应可以引入亚胺二乙酸基团。

In this thesis, three different chain length hybrid monomers, containing acrylate and propenyl ether group, was synthesized by three-step reaction through 1.3-propanediol, 1.4-butanediol, 1.6-hexanediol, allyl bromide and acryloyl chloride.

本文以1.3-丙二醇、1.4-丁二醇、1.6-己二醇、烯丙基溴及丙烯酰氯为主要原料,通过三步反应合成了三种不同链长的丙烯酸酯-丙烯基醚杂化单体。

In this thesis, we want to describe the new one-carbon and three-carbon chain extension and ring expansion of 2-aroyl-3,4-dihydro-2H-naphalen-l-one, which is the first report based on our knowledge.

本文在前人的研究基础上,首次开展了α—芳酰基苯并环己酮增加一个碳原子和三个碳原子的自由基扩环和链增长反应,以及自由基加成成环反应。

The auxiliary can be recovered in high yield (81%) only by filtering and recrystallization. Besides, some other aldehydes have been chosen to test the enantioselectivity of N,N\'-dibenzyl tartamide, in comparison with two other allylaborates reagents developed previously by Roush and Brown, respectively. The results show that %e.e. of homoallylic alcohol is superior to that of the former, and approaches the Brown reagent.

产物经S_N2反应得瑞格列萘中间体-甲基烯丙基-2-氯苯基-叠氮甲烷(17);同时,将筛选出的新型手性配体N-苄基酒石酸二酰胺用于其他几种醛(正丁醛,异戊醛和环己醛)的不对称烯丙基化反应,并与广泛应用的Roush配体(22)和Brown配体(27)相比较,发现其立体选择性优于Roush配体,并接近Brown配体,但明显具有可回收利用的优势。

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