巯基

Some rings were pretreatedwith oxygen radical scavengers or sulfhydryl supplements.

一些动脉环预先给予氧基清除剂或巯基补充剂。

The reaction mechanism of thione-thiol tautomerism for 2,6-dithiopurine obtained from proton transfer has been investigated by DFT B3LYP method with 6-311 ＋G basis set.

采用密度泛函B3LYP方法，在6-311＋G基组水平上对2，6-二巯基嘌呤质子转移引起的硫醇式与硫酮式互变异构反应进行了计算研究。

The reaction mechanism of thione-thiol tautomerism for 2,6-dithiopurine obtained from proton transfer has been investigated by DFT B3LYP method with 6-311＋G basis set. The reaction enthalpies, activation energies, activation free energies and the rate constants of tautomerism were obtained.

采用密度泛函B3LYP方法，在6-311＋G基组水平上对2，6-二巯基嘌呤质子转移引起的硫醇式与硫酮式互变异构反应进行了计算研究，获得了互变异构过程的反应焓、活化能、活化吉布斯自由能和质子转移反应的速率常数等性质。

Based on the above-mentioned, two kinds of target glycoclusters with different glycoterminus, flexible linkers and different scaffolds were designed, disaccharide glycocluster (including TM1-TM7) and trisaccharide glycocluster (TM8-TM9) respectively, with the purpose of obtaining glycoclusters with high binding affinity to anti-Gal antibody and thus better inhibiting the HAR.

基于上述，针对HAR产生的机制，以人体中天然存在的anti-α-Gal抗体及B细胞表面的相应受体为靶点，以α-Gal抗原末端的二糖Galα1→3Gal和三糖Galα1→3Galβ1-4GluNAc片段为糖基部分，采用柔性的连接臂（氨基保护的2-乙醇胺和3-巯基丙酸）和刚性的芳香骨架及柔性的脂肪链骨架，设计了两类结构新颖的糖簇分子：即氧苷和硫苷键连接的二糖糖簇TM1-TM7）和三糖糖簇（TM8-TM9），目的在于寻找与anti-Gal抗体及B细胞相应受体有较高结合力的糖簇分子，以便有效地抑制HAR反应的发生。

It demonstrated that the hydroxy organic acids substituted with-OH,-SH at α—C such as lactic acid, Hydroxy-acetic acid, mercapto-acetic acid, glyconic acid have good selectivity for separation of hematite and aegirine pka values of organic acids fall down because of the-I inductive effect of-OH or-SH, and lie at the pH range between two minerals point-zero-charge. As a result, the depression ability of them was enhanced, and a cyclo-pentyl chelate was formed when this organic acids acted with Fe〓 on the minerals surface.

发现在α位具有-OH、-SH等取代基的短链一元羧酸（乳酸、羟基乙酸、巯基乙酸，葡萄糖酸）对赤铁矿与钠辉石的浮选分离具有优良的选择性抑制作用，-OH、-SH的-I诱导效应导致有机酸的pKa值下降并落在两种矿物零电点之间，使其抑制性能增强，并与矿物表面的Fe〓形成稳定的五元螯合环。

Synthesized three new dithiocarbohydrazones: 1, 5-bis (4-methoxybenzaldehyde) dithiocarbohydrazone (1), 1, 5-bis (p-dimethyl aminobenzaldehyde) dithiocarbohydrazone (2), 1, 5-bis (2-furaldehyde) dithiocarbohydrazone (3), and initially reported the 〓C NMR data of the dithiocarbohydrazones.

合成了3—（谷氨酮—1—基）—4—氨基—5—巯基—1，2，4—均三唑新的中间体化合物，以元素分析，IR，NMR，MS实验技术对其结构进行了表征，研究其NMR波谱特征，并以〓H-〓H COSY，〓C-〓H COSY，COLOC二维NMR技术对其〓H，〓C NMR的谱峰进行了全归属。

In this paper, a series of 4,5-dithiacrown ether annulated 1,3-dithiole-2-thiones 8a~8d were prepared via condensing 4,5-bis-1,3-dithiole-2-thione (7) with 1,ω-dimercapto polyglycol derivatives in high dilution. The obvious template effect was found during the synthesis of 8c-8d.

在高度稀释条件下，经4，5-二溴甲基-1，3-二硫杂环戊烯-2-硫酮(7)和多缩乙二醇的1，ω-二巯基衍生物的缩合反应，方便地合成了4，5-位带二硫杂冠醚残基的2-硫代-1，3-二硫杂环戊烯的衍生物8a~8d，中间体硫杂冠醚8c~8d的合成中有明显的&模板效应&。

The major contents in this thesis are described as follows:(1) Seven new thiol fluorescence reagents containing 2-phenylbenzoxazole (or 2-phenylbenzothiazole) derivatives or benzanthrone as fluorphore and iodinacetylamine or maleimide as reaction groups have been synthesized.

本论文的研究工作主要分为以下几个方面：(1)以碘乙酰胺或马来酰亚胺为反应基团和以2-芳基苯并噁唑类化合物或苯并蒽酮为荧光团，首次合成了七种新的碘乙酰胺类和马来酰亚胺类巯基荧光试剂。

Methods The yield of combinant human IL-18 expression in E.coli remains quite low because the sequence of mature hIL-18 has 37aa rare condons for E.coli in a total of 157aa.

它们的分子中没有N-糖基化位点，不存在二硫键，很可能巯基就是分子的活性中心。

The Sulfhydryl content of glycinin and β-conglycinin are increased with the increasing of pressure and prolong of processed time; Fluorescence analysis reveals that glycinin has larger hydrophobic regions while processed by higher pressure; But to β-conglycinin, the hydrophobic regions change according to different pressure; The changes of ultraviolet difference spectra of pressured glycinin show that amino acid residues which have ultraviolet absorbance are exposed on the surface of the protein molecule with its unfolding by high pressure denaturation as well as the exposure of sulfhydryl and dissulfide groups.

处理压力的升高和时间的延长都将使大豆豆球蛋白和β-伴大豆球蛋白的半胱氨酸残基暴露，巯基含量增加。荧光分析表明，经压力处理后大豆豆球蛋白表面疏水区域增多：而对于β-球蛋白，在低压作用下，其疏水区域减少，在高压作用下，其疏水区域增加，但在过高的压力下，β-伴球蛋白中的疏水区域又呈现减少的趋势。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。