巨脑的

In the brain of adult rat, the positive immunohistochemical product of lSL-l (ISL-l-positive) was mainly located in the neuronal nucleus and found in discrete regions except to brain cortex, such as the Purkinje cell layer and the granular cell layer of cerebellum, the granular cell layer and the pyramidal cell layer of hippocampus, the mitral cell layer, the internal and external plexiform layer, the granular cell layer and the granular cell layer of olfactory bulb and so on, and several nuclei of the hypothalamus, midbrain and pons, such as claustrum, anterior olfactory nucleus, accumbens nucleus, caudate-ptamen, pallidum, substantia nigra, striatum, islands of Callaje, mammillary nucleus, anterior pretactal nucleus, habenular nucleus, amygdaloid nucleus, cuneate nucleus, rubral nucleus, gigantocellular reticular nucleus and so on.

在正常成年大鼠脑中，同源框基因islet-1表达产物（ISL-1）免疫组织化学阳性物质广泛分布于除大脑皮层外的神经细胞的细胞核内，ISL-1阳性神经元密集分布于小脑Purkinje细胞层和颗粒细胞层、海马的颗粒细胞层和锥体细胞层、嗅球的内丛层、外丛层、颗粒细胞层及僧帽细胞层等，另外在丘脑、中脑和桥脑的一些重要神经元核团均有分布，如，屏状核、前嗅核、伏核、尾壳核、苍白球、黑质、纹状体、Calleja岛、乳头体核、前顶盖前核、缰核、杏仁核、楔束核、红核网状巨细胞核等。

Pachygyria is a neuronal migration disorder that develops during the 12th to 24th week of embryologic development, and results in various degrees of muscle spasm, hyperreflexia, seizures, developmental delay, and mental retardation.

巨脑回是一种神经移行障碍，发生于胚胎发育的12-24周，其导致不同程度的肌痉挛、反射亢进、癫痫发作、发育延迟和智力低下

As the reticuloendothelial system begins to react to the hemorrhage, hemosiderin, the crystalline storage form of heme iron, begins to accumulate in macrophages and astrocytes. The pace of this process depends on the ability of a given patient's immune system to mobilize and activate cells which provide this scavenger function; over many years, hemosiderin is removed from the brain.

当网状内皮组织对出血，含铁血黄素以及以晶体形式储存的亚铁血红素产生反应时，就会刺激巨噬细胞和星形胶质细胞清除脑内的含铁血黄素，这一过程的速度取决于患者本身动员和激活吞噬功能的能力。

The CT and MRI manifestations of pachygyria and agyria are presented with a review of the pathological features of the disorders and an evaluation of the diagnostic value of both imaging modalities.

结合巨脑回和无脑回畸形的病理特点，研究两种病变的 CT、MRI表现特征，以评价两种影像学检查方法该病变的诊断价值。

The analyses confirm 7 cases with agyria, 5 with pachygyria of bilateral cerebral hemisphere and 3 with limited pachygyria of unilateral hemisphere.

结果显示：CT、MRI显示无脑回畸形 7例，双侧全大脑半球的巨脑回畸形 5例，单侧大脑半球的局限性巨脑回畸形 3例。

Blood-brain barrier, which is formed by a complex system of cerebral microvascular endothelial cells, astroglia, pericytes, perivascular macrophages, and a basal lamina, plays an important role in maintaining the normal functions of the central nervous system.

血脑屏障是由脑微血管内皮细胞、星形神经胶质细胞、外膜细胞、血管周围巨噬细胞和基底膜组成的一个复杂系统，对维持中枢神经系统的正常功能非常重要。

ABSTRACT Blood-brain barrier, which is formed by a complex system of cerebral microvascular endothelial cells, astroglia, pericytes, perivascular macrophages, and a basal lamina, plays an important role in maintaining the normal functions of the central nervous system.

血脑屏障是由脑微血管内皮细胞、星形神经胶质细胞、外膜细胞、血管周围巨噬细胞和基底膜组成的一个复杂系统，对维持中枢神经系统的正常功能非常重要。

Pachygyria has a distinctive appearance on CT and MRI, including marked thickening of the cortex, broad and flat gyri with shallow sulci, vertically-oriented and shallow Sylvian fissures, and a "figure-of-eight" appearance on axial imaging.

巨脑回畸形在MR和CT上有特征性的表现，包括明显增厚的脑皮质、宽基底扁平的脑回，垂直走行并变浅的大脑外侧裂、轴位像大脑呈8字形改变。

ResultsIn the immune deficit mice ,1.33g/kg Naoshu capsule could enhance the phagocytic activity of monocytes, 0.67g/kg and 1.33g/kg Naoshu capsule could increase content of haemolysin antibody,and decrease footpad swelling induced by cyclophosphamide.

结果1.33g/kg脑舒胶囊能提高免疫低下小鼠单核巨噬细胞吞噬功能；0.67g/kg和1.33g/kg脑舒胶囊能增加免疫低下小鼠溶血素抗体生成，并拮抗环磷酰胺诱导的免疫低下小鼠足垫肿胀度减轻。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。