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巨结肠

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Constipation can be a small number of babies suffering from congenital megacolon, anal fissure, anal atresia and other diseases caused, it is timely to go to hospital for treatment.

少数婴儿便秘可因患先天性巨结肠、肛裂、肛门闭锁等疾病而引起,应及时去医院诊治。

Anatomical variation and damnification in median sacral artery is the main cause for abnormal bleeding when separating the rectum during modified Rehbein radical operation for the treatment of megacolon.

解剖变异的骶中动脉的损伤是先天性巨结肠Rehbein改良根治术中直肠分离异常出血止血困难的重要原因,该动脉损伤引起的出血,应作骶中动静脉结扎。

Some children because of malnutrition, or suffering from rickets, such as hypothyroidism, resulting in the intestinal wall and abdominal wall muscle relaxant, difficult stool from individual children such as congenital megacolon congenital defects, resulting in recurrent constipation.

有的儿童由于营养不良,或患佝偻病、甲状腺功能减退症等,致使肠壁及腹壁肌肉松弛,大便不易排出,个别儿童因先天性巨结肠症等先天缺陷,致使经常便秘。

Keywords:median sacral artery;megacolon;modified Rehbein radical operation;bleeding

关键词]骶中动脉;先天性巨结肠;Rehbein改良根治术;出血

Only few S-100 protein immunoreative nerves can be observed in the place of primary myenteric plexus.

发育早期神经开始在肠壁肌间丛位置出现,发育中期神经成分在肠壁各层中出现并发育增生,晚期肠壁各层神经已分化和成熟,而在不同的发育阶段,原始病因可导致临床表现不一的先天性巨结肠症。

Objective To research the respects of peritoneoscope and ultrasonic surgical knife used for radical operation of congenital giant colon.

目的 探讨腹腔镜与超声手术刀配合在先天性巨结肠手术中的应用前景。

Period,12 cases defecated normally,18 cases undergoing internal sphincter myomectomy and 30 cases undergoing radical excision had good restoration.

结果 均顺利渡过最初危险期,其中12例排便恢复正常;18例行内括约肌部分切除术;30例行巨结肠根治术,术后均恢复良好。

Results Among the 60 cases, all patients past the first riskperiod,12 cases defecated normally,18 cases undergoing internal sphincter myomectomy and 30 cases undergoing radical excision had good restoration.

结果 均顺利渡过最初危险期,其中12例排便恢复正常;18例行内括约肌部分切除术;30例行巨结肠根治术,术后均恢复良好。

Objective This study attempts to elucidate the relationship between RET oncogene and Chinese patients with Hirschsprung's disease.

目的 从分子水平探讨先天性巨结肠的发病机理,了解中国人群HD发病与酪氨酸激酶受体基因突变的关系。

The results of this reseach showed that administration of SF intracolonically had protective effect on the colon injury in the rat model of colitis induced by acetic acid enema, which was probably due to the mechanism of antioxidation, inhibition ofarachidonic acid metabolis and platelets activation, administration of SF intracolonically also showed protective effect on the colon injury in the rat model of colitis induced by trinitrobenzene sulfonic acid and ethanol, which was probably due to antioxidation and inhibition of macrophages activation.

实验研究表明,大鼠分别经乙酸、TNBS和乙醇处理后均出现典型的结肠炎症状,给药后分别评价结肠粘膜损伤指标、结肠组织病理变化,检测结肠组织炎症指标、结肠组织氧化损伤指标及主要炎性细胞因子改变;实验结果:阿魏酸钠对大鼠乙酸性结肠炎结肠粘膜损伤具有缓解保护作用,其机制可能与直接抑制炎症结肠粘膜花生四烯酸代谢过度,抑制血小板活化,清除大量氧自由基有关;阿魏酸钠对大鼠TNBS性结肠炎粘膜免疫损伤亦具有缓解保护作用,其机制可能与抗氧化,抑制结肠巨噬细胞活化有关。

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