巨核

Objectives To explore the early diagnosis of atypical aplastic anemiaby analyzing the characteristic patterns of the megakaryocyte,particles and biopsy of bone marrow.

目的分析不典型再生障碍性贫血患儿的骨髓巨核细胞、骨髓小粒的特点，对其诊断进行探讨。

Objective: To test GPⅡb/Ⅲa and GPⅠb/Ⅸ specific autoantibodies of thrombocytopenic patients by MAIPA assay, evaluate the usefulness of MAIPA for the differential diagnosis of immune and nonimmune thrombocytopenia.

在血小板和巨核细胞膜表面存在大量的糖蛋白分子，它们不仅是血小板发挥功能所必需的，而且在免疫性血小板减少的发病中占重要地位。

The diagnosis of ITP is made clinically by exclusion of other causes of thrombocytopenia, the absence of splenomegaly, and the finding of normal or increased megakaryopoiesis on bone marrow examination. The nonimmune thrombocytopenia is caused by some nonimmune factors, such as acute leukemia, hypersplenism and post-chemotherapic bone marrow suppression.

特发性血小板减少性紫癜的诊断仍只是一种排除性的临床诊断，其国内诊断标准为多次化验检查血小板计数减少，脾脏不增大或仅轻度增大，骨髓检查巨核细胞数增多或正常，有成熟障碍，并且具备以下五点中的任何一点：泼尼松治疗有效，切脾治疗有效，血小板相关抗体增多，血小板相关补体增多，血小板寿命测定缩短，同时应排除继发性血小板减少症。

In vitro,we can harvest a lot of megakaryoctes derived from cord blood in the new two-step method.

在体外，使用种新的两步培养法可获取大量的脐血来源的巨核细胞以供研究使用。

The laboratory findings of a typical CCML patient comprised of peripheral blood leukocytosis, basophilia and eosinophilia,myeloid differentiation in different stages, and increased megakaryocytes. The immunohistochemical features of the CCML consisted of highly positive MPO and CD68, significant lowering of neutrophil alkaline phosphatase, positive for Philadel- phia chromosome or chimeric BCR/ABL gene, etc. But in most cases of juvenile CCML, the Philadelphia chromosome could not be detected.

临床表现以乏力、低热、贫血、肝脾及淋巴结肿大为主要特点；典型儿童慢性髓细胞白血病的实验室特点有白细胞计数高、嗜酸和嗜碱性粒细胞增多、骨髓不同阶段髓细胞分化和巨核细胞增多；免疫组化提示CD68，髓过氧化物酶，中性粒细胞碱性磷酸酶积分明显减低，Ph染色体或BCR/ABL融合基因阳性，而幼年型CCML的Ph染色体常为阴性。

It can expedites proliferation and synthesizing active of cartilage cell and osteoblast too. Quicken ossification in the cartilagines and improving bone repair. But it has no influence to engendering blood vessel.

在骨愈合早期、中期，中药可加强巨核细胞的聚集及增强其活性，并可促进软骨细胞、成骨细胞的增殖及合成活性，加快软骨内骨化，促进骨愈合；而对血管形成无明显作用。

Methods A plasma clot clonal assay, immunocytochemical staining and Western blot were used in this study.

用血浆凝块巨核细胞集落培养，观察对生长的影响，并进一步使用免疫组化和Western blot证实受体的存在和对c-fos表达的影响。

Objective To explore the significant changes of transcription factor GATA- 1 and nuclear factor erygthroid 2 (NF -E2) in megakaryocytes of bone marrow in children with acute idiopathic thrombocytopenic purpura.

目的探讨转录因子GATA-1和NF-E2在急性特发性血小板减少性紫癜患儿骨髓巨核细胞表达水平的改变及其意义。

Objective To investigate the effect of hematopoietic stimulating factors on the expansion of mature megakaryocytes.

目的：探讨造血刺激因子对巨核系成熟细胞体外扩增的影响。

Erythrocyte series proliferated extremely and pathosis hemogenesis existed in bone marrow in all cases.

骨髓红系增生过旺，全部患儿均有病态造血特征，阳性率为粒系占84.6%，红系占94.7%，巨核系39.5%。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失