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General symptoms such as purpure in mucous membrance and skin, bleeding of internal organs, decreasing of weight and bad mental state caused by modeling were well improved in four control groups (Chinese traditional medicine group, western medicine group, PG original formula group and PG major formula group), the peripheral PLT was increased, spleen weight and its action of phagocytosis and damage to PLT were both decreased, morrow megakaryocytes differentiation and maturation were improved and hyperplasia descended, which showed significant differences compared with the model group. Differences among the four control groups were not significant. The optimal dose ratio of PG major formula was finded out with homogeneous design software UST3.0 and multiple regression: Astragalus root 48g, Rhubarb 15g, peach kernel 1Og, Agrimony 24g.

结果:模型建立成功;中、西药对照组、紫癜颗粒核心方组与原方组小鼠对于免疫法造模所引起的皮肤粘膜紫癜、内脏出血、体重减轻、精神状态差等一般症状均有较好的改善;小鼠的外周血小板计数得到提高;脾脏均重及对血小板的吞噬破坏降低;骨髓巨核细胞分化成熟程度增高,增生活跃度降低,与模型组相比较,均有显著性差异,四个对照组之间无显著性差异,利用均匀设计UST3.0统计软件分析,进行多元逐步回归处理,筛选出紫癜颗粒核心方的最佳剂量配比为黄芪48g,大黄15g,桃仁10g,仙鹤草24g。

Pure red cell aplasia is a rare and special type of aplastic anemia.

单纯性红细胞再障是一种罕见特殊类型的再障,血象及骨髓象中仅有红细胞减少而粒细胞及巨核细胞数正常。

Methods 60 patients with newly diagnosed ITP, their serum TPO concentration were detected by double-antibody sandwich enzyme-linked immunosorbent assay; and the bone Marrow megakaryocytes were recorded; HP was detected by 14C urea breath test. The control group of 40 cases was also detected by above methods.

60例初治ITP患者,在接收治疗前采用双抗体夹心酶联免疫吸附法检测血清TPO水平,计数骨髓涂片的平均巨核细胞数量,用14C尿素呼气试验检测患者HP感染情况。

Immune cytochemistry was used to detect GATA - 1 and NF-E2 in megakaryocy...

结论转录因子GATA-1和NF-E2在AITP患儿骨髓巨核细胞的表达增强。

Results The megakaryocyte and platelet of 112 cases hemopathy marrow smear with acetal phospholipids staining were all positive, the plasmas cell in anaemia were positive, the erythroblast of aplastic anemia positive, the lipocyte in thrombocytopenic purpura positive, and the other cells all negative.

结果]112例血液病骨髓涂片缩醛磷脂染色中的巨核细胞和血小板均为阳性,贫血中的浆细胞为阳性,再生障碍性贫血中的幼红细胞为阳性,血小板减少性紫癜中的脂肪细胞为阳性,其余各种细胞均呈阴性反应。

Results There were significant differences between MDS and CAA in Hb, red cell distribution width-coefficient variation, immature reticulocyte fraction, BPC, the ratio of G1 (the sum percentage of myeloblast and premyelocyte) to G2 (the sum percentage of neutrophilic myelocyte and metamy-elocyte), the ratio of E1 (the sum percentage of proerythroblast and early erythroblast) to E2 (the sum percentage of intermediate erythroblast and late erythroblast), megakaryocyte count,erythroblast PAS, neutrophil alkaline phosphatase, and serous levels of indirect bilirubin,lactose dehydrogenase, folic acid, VitBl2 and ferritin.

结果 MDS患者血红蛋白,红细胞体积分布宽度。变异系数、未成熟网织细胞比率、血小板计数、骨髓原始细胞及早幼粒细胞之和与中性中幼粒细胞及中性晚幼粒细胞之和的比值、原始红细胞及早幼红细胞之和与中幼红细胞及晚幼红细胞之和的比值、巨核细胞计数、有核红细胞糖原染色阳性率和阳性指数、中性粒细胞碱性磷酸酶染色阳性率和阳性指数、血清间接胆红素、乳酸脱氢酶、尿酸、叶酸、维生素B12(VitB12)、铁蛋白水平等常规实验室指标与CAA患者比较差异有统计学意义。

MethodsA total of 63 patients with AAA from benzolism who underwent treatment for the first time were investigated for marrow test including myeloproliferative degree, ratio of every hemocyte system, hemocyte division, megakaryocyte count, plasm vacuoles, and hematopoiesis exponent, which were compared with that of those with primary AAA at the same time.

63例初治苯中毒AAA住院病例,入院时行骨髓检查,分析骨髓增生程度、各系的比例、细胞分裂像、巨核细胞数、胞浆空泡及造血指数积分,并与同期收治的原发性AAA作比较。找寻其特点。

It publishes original research reports, reviews in the following areas: cell cycle regulation, cytokines, erythropoiesis, gene therapy, general hematopoiesis, granulopoiesis, hematological malignancies, immunobiology, immunotherapy, lymphopoiesis, megakaryocytopoiesis, microenvironment, monocyte development, molecular genetics, signal transduction, stem cell biology, and experimental as well as clinical stem cell transplantation.

该杂志刊载细胞周期调控、细胞因子、红细胞生成、基因疗法、全身血细胞生成、粒细胞生成、血液肿瘤、免疫生物、免疫疗法、淋巴细胞生成、巨核细胞生成、微环境、单细胞生成、分子遗传学、信号传导、干细胞生物学、实验与临床干细胞移植方面的原始论文及综述等。

Models of K562 cells inducing differentiation to lineages of megakaryocyte, erythrocyte and macrophagocyte were established with inducers TPA (tetradecanoylphorbol 13-acetate), Hu and HMBA respectively.

用Western blot检测以十四烷酸佛波醇-13-乙酯(tetradecanoylphorbol 13-acetate, TPA)、羟基脲(hydooxyurea, Hu)及六甲基双乙酰胺(hexamethylene bisacetamide, HMBA)为诱导剂分别诱导K562细胞向巨核细胞系、红细胞系及巨噬细胞系分化时bcl-6表达变化,用PCR、克隆、直接DNA测序方法分析bcl-6基因5'调控区序列变异情况。

Results The reticulin fibre proliferated in all specimen and most of them occured mega karyocytosis.The myelofibrosis was severer along with the progress of CML,while megakaryocyte counts didn′t change significantly.

结果 发现所有患者的骨髓组织均存在网硬蛋白纤维增多,且随CML进展其程度加重;大多数患者巨核细胞过度增生,在CML不同阶段中巨核细胞数比较未见显著差异。

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They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性,但我大喊,并在他们的方向扔石头让他们过的线索,远离我,以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。

Store this product in a sealed, lightproof, dry and cool place.

密封,遮光,置阴凉干燥处。