巨噬细胞

Methods Models of severe thoracic trauma were established,alveolar macrophages were obtained by collecting broncho alveolar lavage fluid,and then separated and cultured.TLR4 mRNA and the expression of TLR4 protein were measured by northern and western blot before and 2,4,8,16,24h after trauma.

建立大鼠严重胸部创伤模型，支气管肺泡灌洗分离、培养肺泡巨噬细胞，利用Western、Northern分子生物学技术检测创伤前、创伤后2、4、8、16、24小时肺泡巨噬细胞TLR4的表达水平。

However, little isknown about whether Candesartan can stabilize and reduce plaque disrupture bydecreasing the macrophage accumulation and reducing MMP-9 expression in the plaque,moreover, it is not clear about the effect of Telmisartan on AT1/AT2 receptor and MMP-9expression of monocyte-macrophages.

但ARB类药物坎地沙坦是否通过减少斑块内巨噬细胞聚集、降低MMP-9的表达从而稳定斑块并具有预防斑块破裂的作用，以及替米沙坦对单核／巨噬细胞AT1、AT2受体、MMP-9表达的作用如何，目前相关的实验研究较少。

AIM: To investigate the effect of antisense oligonucleotides on expression of macrophage migration inhibitory factor in macrophages.

目的：研究巨噬细胞移动抑制因子反义寡核苷酸对体外巨噬细胞表达MIF的影响。

Rat AAA model was made by perfusion PPE elastase through the abdominal aorta, and the specimen was obtained on postoperativeday 3, 7, 14, 28, respectively. Specific elastic fiber staining was used to observe the disruption of elastic fiber in aortic wall. Immunohistochemistry staining of CD68 was applied to observe the microphage infiltration. The in tisu hybridization and western blot of MCP-1 and MMP-2 were used to study the expression of mRNA and protein. Thus we can analyze the facilitated function of MCP-1 gene to the microphage adherence and infiltration on the earlier AAA.

采用经腹主动脉腔内导管灌注的方法制成大鼠AAA模型，分别于术后3天、1周、2周、3周、4周获取各组大鼠腹主动脉标本，行弹力纤维特殊染色观察动脉壁弹力纤维的破坏情况；行CD68免疫组织化学染色观察动脉壁中巨噬细胞的浸润；行MCP-1及MMP-2的原位分子杂交、Western蛋白质印迹观察二者的mRNA表达和蛋白表达；分析MCP-1基因促进巨噬细胞的黏附、浸润在早期AAA发病中的作用。

RESULTS: Pseudopodia of mononuclear macrophage in the normal control group were intact, nuclear membrane was normal, and nucleoplasm was uniformed.

结果：正常对照组单核巨噬细胞伪足完整、核膜正常、核质均匀；20，100，200 mg/L纳米羟基磷灰石诱导24 h后，单核巨噬细胞具有典型的凋亡形态学特征。

The phagocyte swallows saccharomycetes 30 minutes after to swallow the percentage to be possible to reach as high as 63%.

在巨噬细胞吞噬鸡红细胞和巨噬细胞吞噬酵母菌实验基础上建立一种新的吞噬实验方法。

The team discovered that curcuminoids enhanced the surface binding of amyloid beta to macrophages and that vitamin D strongly stimulated the uptake and absorption of amyloid beta in macrophages in a majority of patients.

研究发现，对于大多数病人，姜黄素类衍生物提高了β淀粉样蛋白与巨噬细胞的表面结合，而维生素D强烈刺激了巨噬细胞内β淀粉样蛋白的摄取和吸收。

The lysozyme activity of pulmonary alveolar macrophages was determined by lysoplate assay method. PAM were obtained from the lungs of 26 normal rats by saline bronchoalveolar lavages.

本文检测了26例大鼠肺泡巨噬细胞溶菌酶活性，酶活性稳定，并与细胞浓度呈直线正相关；大蒜对增强肺泡巨噬细胞溶菌酶活性有显著作用。

Much more prolongation ofsurvival term and improvement of survival rate,as well as appearance of a great dealof lymphocytes around pulmonary metastatic nodes and less pulmonary metastaseswere also observed in murines treated with activated、tumor antigen-pulsedmacrophages contrast to those treated with IL-2 gene-transfected macrophageswithout prior pulse of tumor antigen in vitro.

肿瘤抗原冲击的IL-2基因转染巨噬细胞治疗组小鼠期存活明显延长，肺转移结节明显减少，局部病理显示，肺肿瘤周围出现大量淋巴细胞浸润，我们推测这可能是因为抗原冲击的活化巨噬细胞除了增强对肿瘤细胞直接的杀伤效应外，还对其进行处理加工，将免疫信息传递给周围的淋巴细胞，从而引起其增殖活化，并浸润肿瘤组织中。

Objective To investigate whether modulation of the expression level of CD40L on splenocytes could alter the type of macrophages.

目的检测不同CD40L表达水平的脾细胞对巨噬细胞表型和功能的影响，探讨通过调控CD40L的表达改变巨噬细胞的类型。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。