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巨噬细胞

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Each group of rats was kept in a separate cage. All of the rats drank water freely and were fed on stand food for rats.The experiment lasted 4 weeks. Indexes to be examined are as follows:⑴spleen T lymphocyte transform value,⑵spleen NK cell activation alternation value,⑶abdominal cavity macrophagocyte IL-1 and IL-2 activation alternation value.

所有动物分笼饲养,各组均自由饮水,喂食标准鼠类饲料,实验时间为4周。4周后,ME组和FE组作一次性力竭游泳运动后和其他各组大鼠股动脉放血处死,留取血清,无菌取胸腺和脾脏,行以下指标检测:⑴脾脏T淋巴细胞转化值;⑵脾脏NK细胞毒活性的变化值;⑶腹腔巨噬细胞IL-1的活性变化值和脾脏分泌的IL-2的活性变化值。

But in day 14th and day 28th groups, the ratio of macrophagus positive area in lung interstitium was bigger than that of control group( P 〈0.05 ), with collagen fibers depositing in the lung interstitium gradually.

结论博莱霉素鼠肺毛细血管内皮细胞间紧密连接持续开放,与巨噬细胞在组织间浸润密切相关,并可能是博莱霉素致肺纤维化发生的重要因素。

Results (1) Observation by light microscope:Parts of lung were consolidation in 3rd day and 7th day groups of pneumonia, and macrophagus were prevailing in alveolus.

BLM第3天及第7天组大鼠肺组织实变、出血,其中炎细胞浸润情况与同期肺炎组类似;第14天及第28天组大鼠肺间质内持续存在单核巨噬细胞浸润,其阳性面积比与正常对照组比较差异有统计学意义(P〈0.05)。

Methods The experimental mouse was injected with high, middle, and low dosages of marasmius androsaceus po1ysaccharide 5, 10, 20 mg kg^(-1d^(-1) in the abdomen, and the comparison group was given the same volume of saline water i. p. once a day. After treatment for 14 consecutive days, the blood cell count instrument was used to measure the mice hemogram, the phagocytic function of peritoneal macrophage and the ability of carbon granular clearance were observed., the ability of the spleen lymphocytes proliferation was tested by MTT, and the hemolysin production test was used to evaluate the influence of MA polysaccharide on specific humoral immunity in mice.

小鼠腹腔注射不同剂量的鬼毛针多糖5, 10, 20 mgkg^(-1d^(-1),对照组给予等量生理盐水,每天给药1次,连续14d后,用血细胞计数仪检测小鼠血象;用腹腔巨噬细胞吞噬鸡红细胞实验、碳粒廓清实验观察小鼠吞噬细胞的吞噬能力;采用MTT法测定小鼠脾T淋巴细胞增殖能力;采用血清溶血素形成实验观察鬼毛针多糖对小鼠特异性体液免疫功能的影响。

Expression of TGF-β and bFGF was from mesenchymal cells, macrophages and multinuclear giant cells in the granulation tissue.

肉芽组织中间质细胞、单核巨噬细胞和多核巨细胞表达TGF-β、bFGF。

METHODS: The human monocytic leukemia cell line (THP-1) was chosen in our study. The differentiation of THP-1 cells into macrophages was induced by using phorbol myristate acetate.

体外培养人源单核细胞系THP-1,由佛波酯作用使其分化为巨噬细胞,后者可在氧化低密度脂蛋白存在条件下进一步转变为泡沫细胞。

The results show that Yiliqi can enhance the delayed type hepersensitivity of mouse and phagocytosis of macrophage,and it can also increase the positive rate of peripheral T cell containing acid α-naphthyl acetate esterase and the number of antibody forming cell in spleen.

实验结果表明,小鼠连续20天给与该受试物,在人使用量的1倍、10倍、30倍剂量组能明显增强小鼠迟发型变态反应及增加外周血T淋巴细胞ANAE阳性率,并可提高小鼠巨噬细胞吞噬功能和脾脏抗体生成细胞数。

AIM: To observe the changes in infiltrating macrophagesand extracellular matrix in the kidney in the progressive course of nephrotoxic nephritis.

目的:观察肾毒血清肾炎发病过程中肾组织巨噬细胞浸润与细胞外基质含量的动态变化。

Most of these positive cells were verified as mono-macrophages and neutrophilic granulocytes by electron microscopy.

电镜下证实这些阳性细胞多单核-巨噬细胞和中性粒细胞。

Most of these positive cells were verified as mono-macrophages and neutrophilic granulocytes by electron microscopy.

电镜下证实这些阳性细胞多数为单核-巨噬细胞和中性粒细胞。

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