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Methods: Totally 101 patients with EH and 31 healthy volunteers were enrolled. Systolic peak velocity was measured at basal and middle segments in different left ventricular walls using real-time triplane quantitative tissue velocity imaging.

选择原发性高血压患者101例和健康志愿者31例,应用实时三平面成像技术同时显示心尖四腔心、心尖两腔心和心尖左心室长轴切面,启动定量组织速度成像模式测定左心室各壁基底段和中间段收缩期峰值速度。

Results The patients with cardiac amyloidosis had characteristics of large atriums and hypertrophic ventricular walls in echocardiography. And they also had low limb lead voltage in ECG. The ratio of (SV5+RV1) and left ventricle crossing area of all patients were obviously lower than 1.5. Biopsy behaved staining of congo red. And most patients had renal, dermatic and gastrointestinal involvements.

结果 心脏超声心动图表现为患者左、右心房增大,心室肥厚,心腔正常;心电图表现为肢体导联低电压,心电图电压(SV5+RV1)与左心室横截面积CSA比值均明显小于1.5;心外活检表现为刚果红染色阳性,且大部分患者合并肾脏、皮肤及消化系统损害。

The homodynamic studied on dogs in narcotics show that the mean artery pressure ;ventricular pressure maximal change rate decrease, the left ventricular press ; ventricular pressure maximal change rate ; Coronary blood flow; cardiac output increased after treatment of HISI while left ventricular end diastolic pressure decreased in dogs.

对麻醉犬血流动力学的考查表明,静脉注射苦碟子氯化钠注射液使受试犬平均动脉压、左室内压正向最大变化速率降低,左室内压负向最大变化速率-dp/dt_(max升高,左室舒张末期压降低,左室内压,心输出量及冠脉输出量增加。

9 cases of levoversion and 3 cases of isolated levocardia were investigated.

分析探讨左旋心和孤立左位心的诊断和外科治疗。

There was 4.8±1.7 mean abnormalities in levoversion, 3.0±1.7 in isolated levocardia.

左旋心平均心血管畸形数为4.8±1.8,孤立左位心为3.0±1.7。

Levoversion and isolated levocardia usually accompany with several defects in cardia.

左旋心和孤立左位心的诊断主要依靠肺门切层片或高KV胸片和胸腹部平片。

objective trimetazidine has shown anti-ischemic properties to improve exercise tolerance without haemodynamic effects and direct cyto protective effect on the myocardium.however,it is not clear whether trimetazidine has beneficially effect on severe ischemic cardiomyopathy.methods 19patients(68±9)years with postnecrotic left ventricular dysfunction(ejection fraction31.7%±5.4%)were studied to examine the benefit of adding60mg a day of trimetazidine for3months to the classical therapy.the assessment included clinical evaluation,electrocardiography and echocardiography.results after adding60mg a day of trimetazidine for3months,attack of angina was relieved and dyspnea was improved(p.05).but heart rate,systolic blood pressure,rate pressure product,ejection fraction,left ventricular volume and global wall motion index were not changed.conclusion trimetazidine seems to improve clinical status while can not change oxygen supply-to-demand ratio without adverse effects in patients on severe ischemic carˉdiomyopathy.

目的 曲美他嗪是一种新型的抗心肌缺血的药物,能够改善患者的运动耐量和心肌的直接保护作用同时并没有血流动力学效应。但目前对于严重缺血性心肌病患者的临床治疗价值还需要进一步观察。方法 19例(68±9)岁确诊为缺血性心肌病(左心室射血分数0%)的患者在常规治疗的基础上加用每日60mg曲美他嗪治疗3个月,随诊观察患者临床情况以及超声心动图指标的变化。结果 19例患者均可耐受在常规治疗基础上加用每日60mg曲美他嗪的治疗,随诊发现患者心绞痛发作明显减少,运动耐量明显改善。同时患者心率、收缩压、心率血压乘积、左心室射血分数、左心室容量以及整体室壁运动指数无明显改变。结论缺血性心肌病的患者在常规治疗基础上加用曲美他嗪是安全的,同时其能明显改善患者的临床状态,而这种作用并不改变心肌氧的供求比值。

Methods:A validated three dimension reconstructional echocardiographic technique for endocardial surface area was used to measure the endocardial surface area of the left ventricleand abnormal wall motionin 70 consecutive patients with first AMI.Patients undertook serial echocardiogram on the day 1,3 and 2 weeks,3 and 6 months after admission.

应用超声心动图数据处理系统重建并定量急性心肌梗塞患者的左室心内膜三维面积、异常运动区心内膜三维面积同时测量左室射血分数,系列观察70例患者急性心肌梗塞后左室重塑的动态演变特征及其对左室功能与预后的影响。

There was a good correlation between Ptw,AVCtw,MVOtw,PTV,PUV,UntwR and age.2.Assessment of left ventricular twisting and untwisting of DCM patients19 DCM patients(range 18-80 yr,mean age 50.52±17.52 yr,2 females) and 21 age- and sex-matched normal controls(range18-80 yr,mean age 49.05±16.94 yr,5 females) were enrolled into this study.Then DCM patients were divided into two groups:E/A<2 group and E/A>2 group.The routine echo showed the left ventricle dilated and EF decreased.The results show that LV rotation degree, rotation velocity at baseline and apex were irregular changeable with the cardiac cycle;the rotation direction was clockwise at the base and counterclockwise at the apex,and are combined to yield a systolic counterclockwise twisting as seen from the apex,but the rotation at the basal and apex were the same direction in some patients.

扩心病患者左室扭转及解旋特征的研究选择扩张型心肌病(Dilated Cardiomyopathy,DCM)组患者19例(男性17例,女性2例,年龄18~82岁,平均50.52±17.52岁),健康体检者21例(男性16例,女性5例,年龄18~80岁,平均49.05±16.94岁)作为对照组,扩心病患者按照E/A分为E/A<2、E/A>2两个亚组,结果显示:常规超声显示DCM组LVDd值增大,EF值减小;DCM患者左室心底部与心尖部心肌旋转角度、旋转速度随心动周期变化曲线明显紊乱;与正常组比较,DCM患者左室整体扭转角度和速度分别为(6.49±1.82)°、(67.84±15.60)°/s,较正常人显著减低P<0.01左室舒张末及收缩末扭转角度DCM患者较正常人显著减低(P<0.01,左室舒张末及收缩末时间在DCM-E/A>2组较正常人及DCM-E/A<2组显著缩短P<0.01DCM患者左室解旋速度较正常人亦显著减低(P<0.01,左室功能轻中度减低(DCM-E/A<2)患者解旋率[(0.29±0.07)%]较正常人[(0.42±0.11)%]明显减低,但当左室功能重度减低(DCM-E/A>2)时左室解旋率[(0.63±0.35)%]较正常人反而增加;左室整体扭转角度、舒张末扭转角度、收缩末扭转角度、解旋与左室射血分数未见明显相关性。3。

Measurirg indxes included:(1) Electrocardiograh;(2) Hemodynamics: cardiac output, pump output, aortic pressire, pulmo nary artery pressure, left atrium pressure, right atrium pressure, left ventricular end systolic pressure, left ventricular end diastolic pressure, LV-dp/dt, right ventricul ar end systolic pressure, RV-dp/dt, systolic pressure time index, diastolic pressure time index, endocardial viability ratio;(3) Myocardial metabolism: coronory sinus blood flow, myocardial oxygen consumption, myocardial lactate extractiorn;(4) Ischemic myocardial area;(5) Ultrastructure of myocardium.

测量指标包括:①心电图;②血流动力学:心输出量、泵输出量、主动脉压、肺动脉压、左房压、右房压、左室收缩末压、左室舒张末压、左室压的一阶导数、右室收缩末压、右室压的一阶导数、收缩压力时间指标、舒张压力时间指标、心内膜下心肌供血比率;③心肌代谢;冠状窦血流量、心肌氧耗量、心肌乳酸摄取量;④心肌缺血面积检查及缺血心肌的超微结构观察。

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