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Results: The disintegrating time of Yushi Weiweining concentrated pill was the shortest when the croscarmellose sodium was used for the disintegrating adminicle.

结果:以交联羧甲基纤维素钠的崩解时间最短,在用量为3%时,崩解时间为38min。

Technique characteristics: Libeng(Improved Carboxymethyl Starch Sodium) used to the collapse a degree of hardness for, it having goodly absorbing water dilatability, at the same time having can pressing sex, ameliorable a modeling sex, increment an of the solid product primarily but do not affect its collapse, better than Carboxymethyl Starch Sodium.

技术特点:立崩主要用作固体制剂的崩解剂,它具有良好的吸水膨胀性,同时具有可压性,可改善片剂的成型性,增加片剂的硬度而不影响其崩解性,功能优于普通的羧甲淀粉钠。

Stable pharmaceutical compositions containing 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6] cycloheptic [1,2-b] pyridine and a DCL protective amount of a pharmaceutically acceptable basic salt such as calcium dibasic phosphate and an amount of at least one disintegrant, preferably two disintegrates such as microcrystalline cellulose and starch sufficient to provide dissolution of at least about 80% by weight of the pharmaceutical composition in about 45 minutes and suitable for oral administration to treat allergic reactions in mammals such as man are disclosed.

本发明公开了含有8-氯-6,11-二氢-11-(4-亚哌啶基)-5H-苯并[5,6]环庚三烯并[1,2-b]吡啶和DCL保护量的可药用碱性盐如磷酸氢钙以及其含量足以使至少约80%的药物组合物在约45分钟内溶解的至少一种崩解剂、优选两种崩解剂如微晶纤维素和淀粉并且适于口服给药以治疗哺乳动物、例如人的过敏反应的稳定的药物组合物。

Disintegration time is one of the key parameters to determine whether a product is an ODT.

确定一个产品是否为口腔崩解片的一个方面是测定该产品的崩解时间。

The effect of the change of H/Na ratio in disintegrator Carboxymethyl Starch on its functions such as of water-absorbing, swelling and disintegrating had been described in this article.

本文叙述了羧甲基淀粉(Carboxymethyl starch;CMS)中H/Na比值的改变对崩解剂CMS的吸水溶胀性能和崩解性能的影响。

Determination by volunteers depends on subjective description, taste of no grittiness representing complete disintegration. Moreover, modification of pharmacopoeial disintegration testing methods depends on disintegration without shake, the suspension passing through 10 sieve representing complete disintegration.

志愿者口服试验法以服药后的主观感觉为依据,无粗糙砂砾感即为崩解完全;而崩解度检查方法改进法采用不加振摇的崩解度测定法,片剂全部通过10目筛即为崩解完全。

Bacterial strains were isolated from humus mud by employing the dilution methods. Seven cellulose-degradation Strains marked as B-37, B-35,B-31, B-25, B-17, Z-a, and Z-b were selected according to the hyaloid rings on the medium of carboxymethylcellulose sodium Congo red and their efficacy of decomposing filter paper. Z-b had the strongest ability in decomposing filter paper among the seven strains and 16S rDNA analyzed indecated that it was Stenotroplaomnonas maltophilia owning to 99.8% homology. Comparing clony size of the seven strains in media with different carbohydrates and inorganic salt, we found that the potato extract and inorganic salt which contained CaCl2 0.20, MgSO4 1.25, NaCl5.00,(NH4) SO4 1.30, KH2 PO4 1.35, FeSO47H2O 0.015, Na-EDTA 0.02 were suitable for the bacteria growth.

用稀释法从腐殖泥中分离菌株,根据它们在梭甲基纤维素钠-刚果红培养基上的透明圈直径及对滤纸的崩解能力,获得7株纤维素分解细菌(编号:B-37、B-35、B-31、B-25、B-17、Z-a和Z-b),其中菌株Z-b的纤维素崩解能力最强,分子鉴定结果表明它与Stenotrophomonas maltophilia的16S rDNA序列有99.8%的同源性,初步确定为嗜麦芽窄食单胞菌。

The physical and water-physical parameter of the mudstone is tested.

由不同含水状态下的室内崩解试验发现,紫红色泥岩具有较强的崩解特性,且与岩石的物理状态密切相关,试验得到岩块的力学性质指标和变形特征。

The rate of disintegration and dissolution depended on different composition of excipients such as stuffings, disintegrants, Lubricants and adhesives.

制剂中所含赋形剂如填充剂、崩解剂、润滑剂、粘合剂等不同,即会影响药片崩解和溶出的速度。

Objective: To investigate the effect of various disintegrating adminicles on disintegrating time of Yushi Weiweining concentrated pill.

目的:考察不同崩解剂对於氏萎胃宁浓缩丸崩解时间的影响,并选出最佳崩解剂的使用剂量。

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