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Numerical results show the collisional effects on some physics quantities, such as instantaneous voltages on the electrodes, instantaneous thicknesses of the electron sheathes, spatial distributions of the ion density and the electric field in the sheaths, and instantaneous voltage difference between two electrodes.

数值结果显示了碰撞效应对极板上鞘层的瞬时电压、瞬时电子鞘层厚度、鞘层内的离子密度和动能的空间分布以及两个极板上鞘层电压之差等物理量的影响。

By using of differentially drug release technology, various drug release profiles can be obtained by SOTs, and also, the weight of three layers of SOTs can be accommodated separately with unchanged dissolution profiles, thus, optimal formula which is suitable for tri-layer tableting machine can be achieved.

实验结果表明，通过异步释放技术的使用，可以使渗透泵制剂的释药曲线多样化，同时，该方法还可以在确保最终释药曲线不变的前提下，对三层渗透泵制剂中三个物料层的重量进行分别调节，从而得到最适合于三层压片机打片的三层渗透泵处方。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f_2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuilles law of laminar flow.

因此，本文以难溶性的格列齐特为模型药物，在传统型推拉式渗透泵的基础上，设计并制备了双面打孔型推拉式渗透泵；通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面，对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察，同时，应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究；在此基础上，通过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定，结合流体力学中的Poiseuille层流定律方程，对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此，本文以难溶性的格列齐特为模型药物，在传统型推拉式渗透泵的基础上，设计并制备了双面打孔型推拉式渗透泵；通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面，对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察，同时，应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究；在此基础上，通·药学论文过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定，结合流体力学中的Poiseuille层流定律方程，对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此，本文以难溶性的格列齐特为模型药物，在传统型推拉式渗透泵的基础上，设计并制备了双面打孔型推拉式渗透泵；通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面，对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察，同时，应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究；在此基础上，通过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定，结合流体力学中的Poiseuille层流定律方程，对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

Traditional Web application can be divided into three tiers: presentation tier, business logic tier and data tier.

传统的Web应用大致可以分为简单的三层：表示层，业务层和数据层。

The products were identified by IR,NMR,MS and elemental analysis. In our method,K.OH was used in place of NaOH to synthesize benzyl ester of 3,5-dimethyl-4-hydroxybenzoic acid,2',6'-dimethyl-4'-(n-succinimidyloxycarbonyl) phenyl-acridinium-9-carboxylate was purified on a silica gel column with chloroform/ethylacetate(4:l,v/v) as eluent and further purified by triturating with hexane/acetone(2:l,v/v).The luminescence produced by DMAE-NHS is a flash light with maximumemission at 0.4s and decay half-time of 0.9s. The luminescence intensity is 6.11x10 cps/mol,which is affected by the composition of trigger and surfactant.

DMAE·NHS的合成是本论文的关键和难点，我们对文献方法进行改进：文献方法用氢氧化钠与3，5-二甲基-4-羟基苯甲酸反应制得3，5-甲基-4-羟基苯甲酸钠，再用3，5-二甲基-4-羟基苯甲酸钠与苄氯作用制备3，5-二甲基-4-羟基苯甲酸苄酯，我们用氢氧化钾代替氢氧化钠，使合成取得成功；在合成2'，6'-二甲基-4'-苯基-吖啶-9-甲酸酯时，文献方法对粗产品进行两次硅胶柱层析纯化，第一次柱层析用氯仿/乙酸乙酯(4：1，Ⅴ：Ⅴ)作溶剂和淋洗剂，第二次柱层析用己烷/丙酮(2：1，Ⅴ：Ⅴ)作溶剂和淋洗剂，按照文献方法得到的不是所需要的化合物，我们只进行第一次柱层析纯化，然后用己烷/丙酮(2：1，Ⅴ：Ⅴ)进行研磨，过滤，洗涤，除去溶于己烷/丙酮(2：1，Ⅴ：Ⅴ)的部分，得到所需要的产品。

It shows that the average thickness of the surface layer of crystals,the palisade and cone layer and the eggshell membrane are 20.8,220.8 and 62.5μm,respectively,which accounting for 6.8%,72.6% and 20.6% of the total thickness of the eggshell.There are many vesicular holes in palisade layer with an average diameter of(0.32±0.08)μm(n=30).The function of such holes may be of significant to air exchange.The shape of eggshell pore on the surface layer of crystals is round or ellipsis.The fracture surface of the pore is funnel-shaped.

结果表明：白冠长尾雉卵壳的表面晶体层、栅栏锥体层和壳膜层的厚度分别为20.8，220.8和62.5μm，分别占卵壳总厚度的6.8%，72.6%和20.6%；栅栏层有很多蜂窝小孔，其直径为(0.32±0.08)μm(n=30)；卵壳表面有许多圆形或椭圆形的气孔，可能与胚胎发育过程中的气体交换有关，气孔横断面呈细漏斗状，在其上半部有颗粒状填充物。

By altering the carbon chain length,substitutional group on carbon chain,monoamine cations or biamine cations,metal cation and halide anion,we could adjust the interlayer distance,linear alkyl amines conformation and the interaction between linear alkyl amines and metal halide octahedra.

通过改变直链烷基胺的碳链长度、取代基、单双胺以及无机层的金属离子、卤素离子，可以调控无机层的层间距、烷基链段的排列以及烷基链与无机层的作用力等。

Secondly, by studying the effects of the structural parameter of reinforcement and face plate, attentions are paid to the problems, such as different anchor space, anchor length, shoring obliquity, friction angle and cohesive strength between cable and soil, surface thickness.

其次，通过对筋层和面板的变参数研究，研究了筋层布置间距、筋层长度、筋层支护倾角、筋与土体间的摩擦角、粘聚力、护面板厚度的变化对坝体变形的影响。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。