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Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变,则将导致关节软骨基质成分的丢失和进行性破坏;软骨细胞凋亡与OA的发病密切相关,Fas与NO可各自独立介导软骨细胞凋亡,造成关节软骨破坏;IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子,具有促进细胞生长、增殖与合成等作用,可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用,可促进软骨细胞增殖、分化与蛋白多糖的合成,具有较强的诱导软骨形成的能力,研究表明多种生长因子相互促进、相互抑制,以协同或拮抗方式影响软骨细胞代谢,影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

Hyperplasia look like arch local. Little mesangial cell nuclei showed irregular shape or light pycnosis. Mitochondrion in cytoplasm was mild swelling, crest fragmentated partly.

实验Ⅱ组肾小球毛细血管可见内皮细胞孔,局部轻度增生呈连拱状,系膜细胞少量核不规则或轻度固缩状,胞质内线粒体轻度肿胀,部分嵴断裂。

Object history ; State attributes ; Input attributes ; Evaluation attributes ; Sematic constraints ; Computation tuple sequences; Valid sequence ; Cohesion ; Interval query semigroup ; Recursive unsolvable

对象历史;状态属性;输入属性;评价属性;语义限制;局部限制;计算元组序列;合法序列;粘连;区间查询半群;递归不可解

98 patients were divided into 2 groups randomly. The study group of 52 cases were shotted with NB-UVB twice a week for 4 weeks, and received oral itraconazole(100mg, qd) for 4 weeks. The control group of 46 cases were received oral itraconazole(200mg, qd) for 4 weeks.

将98例患者随机分成两组,试验组52例给予局部照射窄谱UVB,每周2次,连续4周,同时口服伊曲康唑100mg,每日1次,连服4周;对照组46例口服伊曲康唑200mg,每天1次,连服4周。

Methods 91 patients with advanced esophagocadial cancer were divided into two groups: the control group (to receive PDT and local chemotherapy) and the test group (to receive endoscopic splender dilation plus PDT and local chemotherapy).

食管贲门癌患者91例,按治疗方法分为对照组和联合扩张治疗组(经内镜探条扩张联合PDT及局部化疗)。

The 69 subhyaloid hemorrhage crises of diabetes were randomly divided into two groups.45 cases in the combined treatment of traditional Chinese medicine and western medicine group;according to control group,determine the treatment based on differentiation of symptoms and signs in earlier period,intermediate stage,later stage.

两组均常规应用西药、激光光凝治疗。西药常规应用可元,并对症控制血糖、血脂、血压;激光光凝治疗针对有视网膜激光光凝适应症的病例,应用美国科以人公司生产的多波长氪激光器,进行局部视网膜激光光凝或次全视网膜激光光凝治疗。

Surface-based hippocampal morphologic analysesWe found regional atrophy of the lateral and inferior hippocampus area bilaterally corresponding to the CA1 and subiculum hippocampal subfield and reginal expand in the heads and tails bilaterally in aMCI compared with NC.

基于海马表面的形态分析结果aMCI组双侧海马的外侧及下表面可见区域性萎缩,这些区域相当于组织学上的CA1区和下托,此外在双侧海马的头部及尾部可见局部膨胀。

Subordinately come the moderately compacted and moderately cemented DRF3-type reservoirs in the Kongdian Formation, intensely compacted and moderately cemented DRF5-type reservoirs in the middle submember of the second member of the Kongdian Formation, and slightly compacted and moderately cemented DRF1-type reservoirs in the lower submember of the first member of the Kongdian Formation.

潍北油田孔店组储层主要属中压实中胶结的 DRF3型,其次是孔二中亚段发育的强压实中胶结的 DRF5型与孔一下亚段发育的弱压实中胶结的 DRF1型,局部出现其它三种类型的成岩相。

And their fractal figures have been drawn. Meanwhile, to obtain a better visual effect and simulate actual natural scene, software adopts the real color and color palette to enrich figures, and color animated cartoon to change them. To show the self-similarity and infinitive tractility of fractal figures, partial zoom has been made on them. In addition, the software also provides several groups of graphic parameters. Very different fractal figure can be created through slightly changing such parameters.

本文运用分形理论实现多种分形算法,在计算机上生成Mandelbrot集,Julia集,L系统,IFS迭代函数系统等典型的分形图形,同时运用真彩色及调色板技术丰富图形的色彩,实现了色彩动画,使其更真实的模拟自然景物;运用鼠标编程技术实现对图形局部的放大和缩小,体现分形图形的自相似性和无限延展性;提供多组参数,利用分形图形的混沌特性,通过微小的参数变化,生成完全不同的分形图形。

A UV varnish unit some-times installed in-line with a printing machine to perform overall or spot varnishing.

有时,紫外线光油机组是印刷机的一个联动装置,作全面或局部加印光油。

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