局部的

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体，分别为ET-1、ET-2、ET-3、ET-β，而在人主要是ET-1，在生理条件下，ET-1在血浆中含量较低，约为5ng〓，故ET-1不是一个循环激素，而是局部合成释放，局部起作用的活性物质，半衰期约1小时，ET-1是目前已知的最强的血管收缩剂，对静脉的作用比动脉强，在血管床，ET受体有A、B两型，A型主要分布在平滑肌细胞，B型主要分布在内皮细胞，它可以通过旁分泌途径刺激内膜增生，具有有丝分裂原效应，可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩，使静止期SMC进入增殖期，还可以通过信号传导途径，与bFGF、GTF-β、PDGF等生长因子协同作用，起共有丝分裂原作用。

In the presence of L-isoproterenol (through local infusion into area CA1), the theta-pulse stimulation with the parameter of 10 Hz, 150 pulses/train, 1 train, a frequency weakly modifying synaptic strength, induced a robust LTP, and this effect was blocked when DL-propranolol was co-administered. By contrast, the theta-pulse stimulation with the parameter of 5 Hz, 150 pulses/train, 3 train, a frequency strongly modifying synaptic strength, induced a significantly smaller LTP when DL-propranolol was administered into area CA1. Accordingly, DL-propranolol impaired rat's spatial learning in the water maze when infused into area CA1 20min pretraining.

正常情况下对突触传递效能仅有微小调制作用的10Hz的θ节律刺激（每串150个脉冲，1串），在CA1区局部给予L-异丙肾上腺素后，显著地诱导出LTP，这一效应可被DL-心得安所阻断；相反，正常情况下对突触传递强度有显著调制作用的5Hz的θ节律刺激（每串150个脉冲，3串），在CA1区局部给予DL-心得安后，所诱导出的LTP被显著压抑。

At this level, the upward projecting signals to higher-located centres and signals that eliciting spinal reflexes are subjected to complex modulatory effects coming from the descending fibers from supraspinal structures and propriospinal neurons through releasing some neuroactive substances, including neurotransmitters and neuromodulalors.

在这里，来自脊髓上结构的下行纤维和脊髓本身的局部神经元通过释放各种神经活性物质，包括神经递质和调质，对痛信号向高位中枢的上行传递和引起脊髓局部反射的过程，起着复杂的调制作用。

Recent studies of abyssal peridotites show that they are not melt residues of batching or fractional melting of pyrolite directly after melt extraction of MORB. Petrological studies of peridotites from Luobusa ophiolite massif also indicate that the mantle peridotites are not simple residues of primary pyrolite either.

罗布落蛇绿岩橄的镜下观察和岩石化学资料也证明，它不是原始地幔岩经局部熔化后的残余物，而且由来自更深层的地幔过渡带的硅酸盐超高压矿物底辟上升经熔取出玄武质熔体后，再次局部熔化后的残余物。

The present article used a word-by-word self-paced moving window reading paradigm, and participants read sentences such as The key to the {cabinet/cabinets}{was/were} rusty from many years of disuse. When the head noun, local noun, and verb were all singular, reading times after the verb were faster than when either a plural local noun or plural verb was present.

本文通过逐词自定节奏移动窗口实验向受试呈现并要求他们阅读The key to the {cabinet/cabinets}{was/were} rusty from many years of disuse一类的句子研究了句子理解中的主语-动词一致的认知加工机制，发现主要名词和局部名词以及动词均为单数时，对动词的加工较快，而出现复数局部名词或复数动词时则动词后成分的加工则较慢。

The thesis consists of three parts:The first part deals with optimal Sobolev inequalities on compact Riemannian manifolds;the second part is concerned with some variational models in image processing,and we propose variational models as well as experimental results for detection,denoising and mosaicking;the last part deals with inverse differential geometry in 3-D non-local image restoration.

本论文由三个部分组成。第一部分是流形上的非线性分析：第二部分是基于能量极小化方法的图像处理；第三部分是三维非局部图像重建及逆向微分几何。在第一部分中，我们研究了紧致流形上的最优Sobolev不等式，证明了某些不等式虽然就整体而言是不成立的，但总是局部成立的。

By employing coordinate transformation, the overall generalized displacement vector relevant to the motion of pad and axle journal is converted into axle journal displacement vector in a local motion coordinate system, and the oil film force in a partial motion coordinate system is obtained by solving the dynamic characters of a fixed bush bearing.

通过坐标变换，将瓦块和轴颈运动相关的全局广义位移矢量转换为局部动坐标系下轴颈的位移矢量；利用求解固定瓦轴承动力特性的方法求得的局部动坐标系下的油膜力。

Based on the summarizing of the algorithms of subdivision surface by Catmull and two-part texture mappings by Biers, this papers goes deeply into features of local texture mapping and the exiting problem, two kinds of local texture mapping methods are presented according to different topology surface.

本文在总结了Catmull的分割面片算法和Bier等的两步纹理映射算法基础上，深入研究了局部纹理映射的特点及目前存在的问题，提出了针对不同拓扑关系表面的两种局部纹理映射算法。

The reciprocal effects between the frequency veering and the sensitivity ofmistuning for a bladed disk are studied. The investigation is based on a finite elementmodel. The reason and features of frequency veering of the bladed disk are analyzed.By using the localization parameter, the effects of mistuning on the system modallocalization of the bladed disk are analyzed in the frequency veering region.

分析了叶盘系统频率转向现象产生的原因及其特点；利用本文提出的模态局部化参数，研究了频率转向区域内叶盘系统的高密集模态对失谐的敏感性；分析了频率转向区域内失谐叶盘系统的振动响应局部化特性。

Design on the principle that security , economy are rational , esthetic , fix up the selection of structure and structural level of every floor, assign , turn into with PK software AutoCAD revise the part behind the structural level well; Adopt stair and floor calculating and designing a teacher to appoint by hand, and calculate the appointed floor with PKPM software, compare with the floor that calculates by hand, fetch the drawing construction drawing of the head of the two; Calculate by hand the frame which the teacher appoints loads, set up good PKPM and calculate the procedur

设计以安全、经济合理、美观为原则，进行结构选型和各楼层结构平面布置，用PK软件布置好结构平面后再转到AutoCAD上进行局部修改；采用手工计算设计老师指定的楼梯和楼板，并用PKPM软件计算指定楼板，与手工计算的楼板进行比较，取二者之长绘制成施工图；手工计算老师指定的框架荷载，建立好PKPM计算框架程序模型，用PKPM计算框架内力并输出文件结果，把PKPM计算得到结构配筋图转到AutoCAD进行局部处理；从PKPM得出的框架构件内力组合，选择三组最不利的组合作为基础设计资料，进行手工设计基础，并用AutoCAD绘制得出基础详图及配筋。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。