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Part Ⅱ Objective: To study the immunoprotective and the immunotherapic effects of the new nucleic acid vaccine of the hepatitis B: pVAX1-C3d-S2S; respectively in normal and HBV transgenic mice after being inoculated intra- muscularly with this Eukaryotic Expression Plasmid, such as the in situ production of the expressed protein in muscle tissue section and specific humoral immune response in normal mice、the variation of specific antigen、antibody and HBV DNA, especialy the changes of specific antigen in liver.

第二部分新型乙肝核酸疫苗pVAX1 C3d-S〓S免疫预防效应和治疗作用的研究目的:研究含有新型分子佐剂补体C3d的HBV adw血清型的乙肝核酸疫苗重组真核表达质粒pVAX1-C3d-S〓S接种正常BALB/c小鼠和HBV转基因小鼠后,其免疫预防作用(接种局部肌肉中特异性抗原蛋白的表达和所诱生的体液免疫应答规律)以及免疫治疗作用(血清中特异性抗原的表达、特异性抗体的产生、HBV DNA的消长和肝组织中抗原表达的变化)。

Bacterial pyrogen was injected into denervated rabbbitear and novocain blocked rabbit knee joint capsule to see whether pyrogen induces fever through nervous reflex mechanism via local receptors or not.

为观察细菌致热原是否通过局部感受器——神经反射机制引起发热而进行下列实验:把细菌致热原注入去神经兔耳和完整神经兔耳皮下;把细菌致热原注入事先用奴弗卡因封闭的兔膝关节囊和事先注射生理盐液的兔膝关节囊;分别比较两组动物的发热效应。

Because of the effect of orientation orders on the distribution of the reactive group, which was called the " pseudo-concentration effect ",the concentration of the reactive group in the ordered domain was higher than that in the isotropic domain.

当体系中出现了介晶基元的有序排列时,与之相连的反应基团的分布也受到影响,有序区内的局部浓度将变大,产生假浓度效应,并最终影响扩散控制反应动力学。

The iron nanoparticles in inner core have good magnetism and targeting heating effect. The temperature can go up to 52 ℃ in the case that 0.1 g carrier (carbon-coated iron nanoparticles) is injected in a local point of pig's liver,while the temperature can go up to 42℃ in the case that pig's liver uniformly containing carrier of 0.4 wt.% and 45℃ in the case that pig's liver uniformly containing carrier of 0.6 wt.%. Carbon-coated iron nanoparticles also has good antioxidation and stability by an X-rays diffraction structural analysis.

铁纳米粒子磁场强,靶向效果好,有较佳的磁靶向发热效应,在动物病灶局部放置0.1 g碳包铁纳米粒子将能使发热温度平均升到52℃;而将碳包铁纳米粒子均匀与猪肝混合也有明显的产热效果:含量0.4%碳包铁纳米粒子的一组猪肝能将温度升到42℃,而含量0.6%碳包铁纳米粒子的一组猪肝能将温度升到48℃。X射线衍射表明借助于碳的包裹,碳包铁纳米粒子有好的抗氧化性和稳定性。

Our results indicate that EA has an inhibitory effect on the BK-induced pressor and ischemic dysfunction, which may be related with endogenous opioid peptide.

结果表明,电针能够抑制BK诱发的升压反应和改善局部心肌运动功能,该效应与内源性阿片肽有关。

The C response of semimembranous and semitendinous myoelectricity evoked by stimulation to rat intraplanta with high intensive currents was used to illustrate the peripheral analgesic effect of BmK when given in local cutaneous sensory fields.

方法采用局部皮肤感受野给药,以强电流刺激大鼠后肢趾部诱发半膜半腱肌发放C反应,观察对外周神经系统的镇痛作用;经脊髓蛛网膜下腔给药,以大鼠足跖辐射热痛阈的变化为中枢镇痛效应的观察指标。

The effect of length due to shear localization is studied.

研究了由于剪切局部化而引起的试件长度的尺寸效应。

In order to overcome the disadvantage of volume effect and improve prospecting precision of MT, the paper puts forward a multi-channel telemetry method of stratum resistivity for linearity processing exploring depth and electromagnetic frequency in the local area, which creates a crresponding relationship between stratum resistivity and sounding line, and a multi-channel observation system is designed accordingly to explore the resistivity of underground ledge.

为克服大地电磁勘探中"体积效应"的缺点,提高探测精度,提出多道遥测地层电阻率法,该方法是在一个局部区域内,将勘探深度和电磁波周期进行线性化处理,使得地层电阻率和测深曲线建立对应关系,并据此设计了一个多道探测地下矿层电阻率的观测系统。

The empirical mode decomposition method is introduced to extract the trend item of gyro's drift, but the local mean estimation isn't precision and the end effects exist in the conventional EMD method. The two-tap adaptive time-varying filter and the adaptive border estimation are used to modify the EMD. After the trend extraction, the method of time series analysis is used to make the autoregressive moving average model for stationary time series.

根据陀螺漂移的特性,提出采用经验模分解的方法对其趋势项进行提取,但传统的经验模分解方法存在局部均值估值不准,插值过程存在端点效应的问题,因此,本文又引入二拍自适应滤波及自适应边界估值来对原方法加以改进;在成功提取趋势项后,通过采用时间序列的分析方法,建立了陀螺漂移平稳时间序列的自回归滑动平均模型;并得出陀螺漂移模型可近似为常值加一阶马尔可夫过程这样一个结论。

Strontium 90 is an isotope with shorter radiation distance and dramatic local bioeffects which can occlude the vessels at the early stage. So it is acceptable by the patients for its simple usage and satisfactory effect.

结论90锶利用其射程短、局部生物效应强的特点作用于瘤体的浅表组织,使扩张之血管早期退缩、闭塞后失去血液供应而达到治疗目的,其治疗方法简便,效果好,患者易于接受。

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