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Abstract] objective to observe the effects of indapamide and losartan alone and combined treatment on the elder patients with hypertension,hypokalemia,hyperglycemia,uric acid,lipid,ect.methods one hundered and fifty patients with hypertension were randomly divided into three groups,with each of 50 cases.the levels of blood pressure,hypokalemia,blood sugar,uric acid,lipide were examined before and after treatment.results after 8 weeks the systolic and diastolic blood pressure were significantly lower.antihypertensive treatment group is the best,the levels of hypokalemia is lower after treatment in the indapamide group,the levels of uric acid is also lower in the losartan group and antihypertensive group.conclusion losartan and indapamide combined treatment not only coordinate to decrease blood pressure but also reduce uric acid,reduce the effect of hypokalemia caused by indapamide.

目的 观察氯沙坦与吲哒帕胺单独应用或联合用药对原发性高血压患者血压、血钾、血糖、尿酸、血脂的影响。方法将符合诊断标准的150例老年高血压患者电脑随机分为3组,每组50例,进行用药前后自身对照试验,8周后检测各组血压、血钾、血糖、尿酸、血脂值。结果 3组治疗后收缩压和舒张压均较前明显降低,联合治疗组降压幅度最大,氯沙坦组和联合治疗组治疗后尿酸值较治疗前降低,吲哒帕胺组治疗后血钾值较治疗前降低。结论氯沙坦与吲哒帕胺联合应用不仅具有协同降压作用,而且能降低尿酸,减轻吲哒帕胺引起的低钾血症。

Cheng Weili,Ding Mingmin,He Qiang,et al.The First Sanatorium of Jinan Military Aera,Qingdao266071. Objective To study the correlation of serum uric acidand lipid in the hyperlipidemia comˉplicated with hyperuricemia.

目的 检测高尿酸合并高脂血症患者血清尿酸、胆固醇、甘油三酯、高密度脂蛋白的含量,以了解其含量变化以及相互关系和影响。

Cheng Weili,Ding Mingmin,He Qiang,et al.The First Sanatorium of Jinan Military Aera,Qingdao266071. Objective To study the correlation of serum uric acidand lipid in the hyperlipidemia comˉplicated with hyperuricemia.Methods We measured UA and lipld by Bayer RA-1000automatic biochemical anaˉlyzer.

目的 检测高尿酸合并高脂血症患者血清尿酸、胆固醇、甘油三酯、高密度脂蛋白的含量,以了解其含量变化以及相互关系和影响方法采用Bayer公司的RA-1000型全自动生化分析仪和国产试剂盒进行测定。

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