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Because corticosteroid can modify the immunological process which is considered the major mechanism involved in AHS, it is used to treat AHS clinically. However, corticosteroid therapy may have deleterious effect (e.g., delayed healing of cutaneous lesions, infections, prolonged hospital stay). Therefore, the use of corticosteroids for AHS remains controversial. We reported a 54-year-old man who had underlying diabetes mellitus with chronic renal insufficiency, hypertension and hyperlipidemia. Allopurinol 100mg twice a day was initiated one month prior to admission. After taking the drug for 24 days, he developed a generalized mild itchy eruption on the trunk and upper extremities followed by chillness, fever, ocular discomfort and painful oral ulcer over one-week period and was admitted to the hospital. A skin biopsy revealed changes consistent with Stevens-Johnson syndrome.

本文报告一位54岁的男性患者,有高血压、高血脂、糖尿病及慢性肾脏功能不全的病史,最近发现有高尿酸血症(11.1mg/dL)而开始服用Allopurinol,在服用24日后,因为逐渐发生皮肤红疹搔痒、口腔溃疡、发烧、畏寒以及眼睛不适,一周之后到医院就医,经诊断为服用Allopurinol所造成之史帝文森-强生症候群(Stevens-Johnson syndrome),因而在皮肤科住院接受治疗,由於病人有高血压、高血脂及糖尿病,所以入院后仅以支持疗法,并未给予全身性类固醇,然而病人之病况恶化,并有肾功能恶化,因而於住院两日后,转进肾脏科病房,在使用全身性类固醇治疗之后,病况持续改善,并在2周后出院。

Urinary NAG is a early Diagnostic indicator of renal damage in patients with hyperuricosuria, especially for gouty kidney.

提示尿NAG可作为高尿酸血症患者早期肾功能损害的观测指标,尤其对痛风肾的早期诊断有重要意义。

In the use of diuretics in the treatment of hypertensive patients, but also about 40% to 50% of people with hyperuricemia.

在使用利尿剂治疗的高血压患者中,也有约40%~50%的人伴有高尿酸血症。

Methods 26621people who received medical check-up in Guangdong Provincial People's Hospital were included in this analysis.

随机抽取2004年在广东省人民医院健康体检人群26621例的资料进行高尿酸血症患病率及相关疾病的发生率统计分析。

Diagnostic standard of MS by international diabetes federation makes the waist circumference as the main diagnostic condition,which showed that neurohumor immunological disorder resulting from abnormality of lipid factors secreted by lipocyte in accumulated fat of internal organs maybe the common pathophysiological basis of Ms and hyperuricemia.

国际糖尿病联盟在MS的诊断标准中将腹围作为主要诊断条件,提示内脏脂肪蓄积引起脂肪细胞分泌脂性因子异常造成的神经体液免疫紊乱可能是高尿酸血症以及MS共同的病理生理学基础。

Objectives: The purpose of this study was to determine the purine content in commercial alcoholic beverages retailed in Taiwanese domestic markets.

目标:本研究是为探讨国内市售酒精性饮料中嘌呤的含量,藉以了解其可能对高尿酸血症和痛风的影响。

VLDL can downregulate the expression of the hOAT1gene possibly induced by lipodystrophy easily acting with hyperuricemia.

VLDL可下调hOAT1mRNA的表达,可能与脂代谢紊乱易合并高尿酸血症有关。

ConclusionsVLDL can downregulate the expression of the hOAT1gene possibly induced by lipodystrophy easily acting with hyperuricemia.

结论VLDL可下调hOAT1mRNA的表达,可能与脂代谢紊乱易合并高尿酸血症有关。

In recent years along with the high uricacidemia disease incidencerate gradual rise, the Chinese medicine and the modern medicine inunceasingly was also thorough to this kind of metabolism diseaseunderstanding and preventing and controlling.

近年来随着高尿酸血症发病率的逐渐上升,中医药和现代医学对这种代谢性疾病的认识和防治也在不断地深入。

Such tophi can destroy the joint and adjacent bone as seen here radiographically in sequential radiographs of the same foot (the patient did not have two right feet).

这种痛风石会破坏关节及相邻的骨,图示的两张X线片均为病人右足(只不过做了两次X线拍摄),大多数但非所有情况会有高尿酸血症。

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