尿酸血症的

In recent years, as rapid development of economy, people living standard rises gradually, dietary structure is changed, the year after year of incidence of a disease of disease of acerbity blood of high make water rises, it is the common unusual index in check-up.

近年来，随着经济的快速发展，人民生活水平逐渐提高，饮食结构改变，高尿酸血症的发病率逐年上升，是体检中常见的异常指标。

Objective:To observe the process of high adenine diet causing hyperuricemia in wistar rats,and to make clear the effect of dietotherapy in disease prevention and control.

目的：观察wistar大鼠高嘌呤饮食诱发高尿酸血症的过程，明确饮食治疗在疾病预防和控制中的作用。

Therefore, IR is common significant pathophysiology foundation of multiple metabolic disease,such as:hyperuricemia,diabetes mellitus,hypertension,and so on.

目前研究的主要结果是：IR与高尿酸血症的发生、发展、治疗及预后有密不可分的关系，高尿酸血症与胰岛素抵抗密切相关［1］。

Uygur national males have greater risk for the kidney harm, the high lipemia, the high blood sugar and the hypertension, should stregthern prevention and therapy.

维族男性高尿酸血症患者容易伴发肾损害、高脂血症、高血糖和高血压，应加强对高尿酸血症的防治。

To be controlled effectively and prevent disease of acerbity blood of high make water, center of check-up of the first hospital began fontal state city actively in check-up the healthy education of disease of acerbity blood of high make water.

为了有效控制和预防高尿酸血症，泉州市第一医院体检中心在体检中积极开展了高尿酸血症的健康教育。

Logistic regression analyses found tha tnationality, FINS, Hypertriglyceridemia, Hypercholesterolemia,BMI,serum Leptin, hypercholesterolemia, hypertriglyceridemia, low HDL cholesterol, diabetes, hypertension occupation, like drinking broth and chicken soup may be the risk factors ,and eating muscle, drinking milk, may be the protect factors of primar y hyperuricemia.

Logistic回归分析发现喜欢吃精瘦肉类和乳制品为高尿酸血症的保护因素，而患有高甘油三脂血症、胰岛素抵抗、高胆固醇血症、从事商业工作、高血压、喜欢喝肉汤鸡汤者以腰臀比较大、血清Leptin浓度较高可能是原发性高尿酸血症的危险因素。

Methods Acteoside was extracted from roots of Scrophularia ningpoensis .

从玄参根中分离提取苯丙素苷成分Acteoslde，采用矿黄嘌呤造成小鼠高尿酸血症，观察Acteoside对小鼠高尿酸血症的影响，并进一步从体外观察Acteoside对黄嘌呤氧化酶的冲制作用。

MethodsSixty Wistar rats were divided into 2 groups randomly: normol group(n=12), and model group(n=48).The model rats were fed with high fat-sugar diet for 6 weeks, then fed with adenine(100 mg·kg-1·d-1) and ethambutol(250 mg·kg-1·d-1) for 2 weeks to induce the IR and hyperuricemia model.

方法选用 60只成年Wistar雄性大鼠，随机分成正常对照组（12只）和模型组（48只），模型组给予高脂高糖饲料餵养6周，6周后再用腺嘌呤〔100 mg/kg·d）〕加乙胺丁醇〔250 mg/〕灌胃2周，造成胰岛素抵抗并高尿酸血症的大鼠模型。

MethodsSixty Wistar rats were divided into 2 groups randomly: normol group(n=12), and model group(n=48).The model rats were fed with high fat-sugar diet for 6 weeks, then fed with adenine(100 mg.kg-1.d-1) and ethambutol(250 mg.kg-1.d-1) for 2 weeks to induce the IR and hyperuricemia model.

方法选用 60只成年Wistar雄性大鼠，随机分成正常对照组（12只）和模型组（48只），模型组给予高脂高糖饲料喂养6周，6周后再用腺嘌呤〔100 mg/kg·d）〕加乙胺丁醇〔250 mg/〕灌胃2周，造成胰岛素抵抗并高尿酸血症的大鼠模型。

To warn that patients are receiving this medication at the same time not to use the excretion of uric acid can inhibit the antihypertensive drugs, such as Thiazide diuretics, including thiazide-type diuretics, as well as the compound preparation of salicylic acid drugs Astemizole aspirin, etc.

需提醒的是，患者在服用此药物的同时，不宜使用可抑制尿酸排泄的降压药物，如噻嗪类利尿剂、含噻嗪类利尿剂的复方制剂以及水杨酸类药物，以防止高尿酸血症的发生。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。