尿酸血症

Therefore, IR is common significant pathophysiology foundation of multiple metabolic disease,such as:hyperuricemia,diabetes mellitus,hypertension,and so on.

目前研究的主要结果是：IR与高尿酸血症的发生、发展、治疗及预后有密不可分的关系，高尿酸血症与胰岛素抵抗密切相关［1］。

MethodsThe same dosage of hypoxanthine, different uricase inhibitor are used singly or combined to replicate hyperuricemia model, inspect the uric acid in serum at different periods of time.

方法采用相同剂量次黄嘌呤，不同剂量尿酸酶抑制剂单次和连续给予复制代谢性高尿酸血症模型，测定造模后不同时段大鼠血尿酸值。

A method of screening serum of patients of gout and hyperuricemia includes checking purine compound content of xanthine and hypoxanthine in serum to be tested, confirming that serum to be tested is serum of gout patient if xanthine content of 1.00-2.35 mg / L and / or hypoxanthine content of 4.1-16.00 mg / L are contained in serum to be tested and confirming that serum to be tested is serum of hyperuricemia patient if xanthine content of 0.20-1.20mg/L and / or hypoxanthine content of 1.30-3.50mg/L are contained in serum to be tested.

本发明所提供的筛查痛风疑似患者及高尿酸血症疑似患者血清的方法，是检测待测血清中包括黄嘌呤和次黄嘌呤在内的嘌呤化合物的含量，如待测血清中黄嘌呤含量为1.00-2.35mg/L，和/或次黄嘌呤含量为4.1-16.00mg/L，则待测血清为痛风疑似患者血清；如待测血清中黄嘌呤含量为0.20-1.20mg/L，和/或次黄嘌呤含量为1.30-3.50mg/L，则待测血清为高尿酸血症疑似患者血清。

In general,the recommendatory dose of 2 g/d is safe for human beings.This does not cause abnormal rise of serum uric acid level,which leads to hyperuricemia and gout.

饮食核酸可影响血尿酸水平；成人日补充量 2 g/d是安全的，不会引起血尿酸水平的异常持续性升高而产生高尿酸血症和痛风。

To be controlled effectively and prevent disease of acerbity blood of high make water, center of check-up of the first hospital began fontal state city actively in check-up the healthy education of disease of acerbity blood of high make water.

为了有效控制和预防高尿酸血症，泉州市第一医院体检中心在体检中积极开展了高尿酸血症的健康教育。

Methods The adsorbing effect of montmorillonite was observed in vitro and the effect of decreasing serum concentration of uric acid was studied on acute hyperuricemia model mice. The concentration of uric acid was measured by the reduction method of phosphotungstic acid.

用离体实验研究蒙脱石对尿酸的吸附作用；用小鼠高尿酸血症模型研究蒙脱石降低血尿酸的作用；用磷钨酸还原法测定尿酸含量。

Methods Acteoside was extracted from roots of Scrophularia ningpoensis .

从玄参根中分离提取苯丙素苷成分Acteoslde，采用矿黄嘌呤造成小鼠高尿酸血症，观察Acteoside对小鼠高尿酸血症的影响，并进一步从体外观察Acteoside对黄嘌呤氧化酶的冲制作用。

Uricase inhibitor was given subcutaneously by lanolin mixed with olefin in acute animal model with Hyperuricemia on rat, which has the characters of high uric acid and maintaining a long time.

以羊毛脂石蜡油（质量比3：2）为溶剂配制尿酸酶抑制剂，采用皮下注射的方法造模，所复制的大鼠代谢性高尿酸血症模型具有血尿酸值高、维持时间长的特点。

Objective:To investigate the influence of different contents of purines in diets on serum uric acid and its excretion in hyperuricemic elderly men.

目的：探讨不同嘌呤含量饮食对老年男性原发性高尿酸血症血尿酸及肾脏尿酸排出的影响。

It has been indicated from epidemiology and clinic research that hyperuricemia and hypertriglyceridemia are risk factors resulting in cardiovascular diseases. Even more, the foul-up of uric acid and triglyceride will aggravate cardiovascular or cerebrovascular diseases.

流行病学调查和临床研究表明，高尿酸血症和高甘油三酯血症是引发心血管疾病的危险因子，尿酸和甘油三酯交互紊乱更是诱发和加重心血管疾病的重要危险因素。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。