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尿酸

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MethodsThe same dosage of hypoxanthine, different uricase inhibitor are used singly or combined to replicate hyperuricemia model, inspect the uric acid in serum at different periods of time.

方法采用相同剂量次黄嘌呤,不同剂量尿酸酶抑制剂单次和连续给予复制代谢性高尿酸血症模型,测定造模后不同时段大鼠血尿酸值。

AIM To determine the optimal doses of hypoxanthine and uricase inhibitor oxonic acid potassium salt for establishment of hyperuricemia rat model, and provide experimental evidence to prepare continual hyperuricemia and gout animal model.

目的 确定次黄嘌呤与尿酸酶抑制剂氧嗪酸钾伍用制备高尿酸血症大鼠模型的合适剂量,为制备持续性高尿酸血症及痛风大鼠模型提供实验依据。

During the 90 min experimental period, urine was collected in 10 min intervals and perfusate was collected at the midpoint of these intervals.

目的为建立发现和评价促尿酸排泄药物作用的离体模型,采用离体大鼠肾脏灌流技术,观察尿酸在离体肾脏中排泄特点和丙磺舒对尿酸排泄影响。

In general,the recommendatory dose of 2 g/d is safe for human beings.This does not cause abnormal rise of serum uric acid level,which leads to hyperuricemia and gout.

饮食核酸可影响血尿酸水平;成人日补充量 2 g/d是安全的,不会引起血尿酸水平的异常持续性升高而产生高尿酸血症和痛风。

In this condition , monosodium urate or uric acid crystals are deposited on the articular cartilage of joints , tendons and surrounding tissues due to elevated concentrations of uric acid in the blood stream .

在这种情况下,单尿酸尿酸晶体沉积在关节软骨的关节,肌腱及周围组织,由于高浓度的尿酸在血液里流。

The present invention uses isocyanuric acid as main raw material, and adopts the following main steps: adding alkali to make solvation, chlorization, bromation, secondary chlorization, filtering and drying to prepare bromochloro-isocyanuric acid.

本发明公开了一种溴氯异氰尿酸消毒灭菌剂的制备方法。该方法以异氰尿酸为主要原料,通过加碱溶解、氯化、溴化、再氯化、过滤、干燥主要步骤制备溴氯异氰尿酸

The levels of blood lipid, blood sugar and hematuria acid were compared in the fatty and nonfatty groups according to BWI. The levels of blood lipid, blood sugar and hematuria acid were also compared in the two groups according to sex and BWI.

对4640例体检者检查资料进行整理分析,按性别、年龄分组,比较体重指数与血脂、血糖和血尿酸的水平;按BMI分为肥胖组和非肥胖组,比较两组之间血脂、血糖和血尿酸的水平;进一步按性别和BMI比较两组之间血脂、血糖和血尿酸的水平。

Methods: After the sorting and analysis of data in the physical examination of 4640 cases, the comparisons between the BMI and blood lipid, the levels of blood sugar and hematuria acid were compared in the groups according to sex and age. The levels of blood lipid, blood sugar and hematuria acid were compared in the fatty and nonfatty groups according to BWI. The levels of blood lipid, blood sugar and hematuria acid were also compared in the two groups according to sex and BWI.

对4640例体检者检查资料进行整理分析,按性别、年龄分组,比较体重指数与血脂、血糖和血尿酸的水平;按BMI分为肥胖组和非肥胖组,比较两组之间血脂、血糖和血尿酸的水平;进一步按性别和BMI比较两组之间血脂、血糖和血尿酸的水平。

Objective To study the content of uric acid in serum, to screen the uricemia patients, and to avoid the diseases caused by uricemia. Methods An enzymetic colorimetric method was used to determine uric acid of 2 525 middle school students in Shanghai.

目的 了解中学生血清尿酸含量,以便尽早发现高尿酸血症患者,避免由此引起的疾病方法采用酶比色法,应用日立-7150型全自动生化分析仪上对上海市2 525名中学生的空腹血清进行尿酸测定。

The uricase is a kind of enzyme in the purine degeneration pathways of organism, the uric acid can be oxidated in allantoin, CO2 and H2O2, human does not have the uricase, therefore the uric acid accumulates in the vivo clinical organism such as the pathological change like gout.

摘要] 尿酸酶是生物体内嘌呤降解代谢途径中一种酶,尿酸氧化生成尿囊素、CO2和H2O2,人体中没有尿酸酶,因此尿酸在体内的积累会出现临床机体的病变如痛风。

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