尿酸

Initial stage of disease of acerbity blood of high make water can not have any symptoms, but the part can evolve and cause acute arthritis, chalkstone, kidney stone and uric acid nephrosis. The content that 3 health teach 3 · 1 balanced diet, reducing acid of make water of tall purine food is the final result that purine metabolizes, fructose is absorbed can bring about acid of nucleotide of purine of the gland inside body to produce increase too much, promote make water to be generated acerbitily then, reason should be fed less contain the food with much fructose, the intake of daily purine should 50 Mg.

高尿酸血症初期可无任何症状，但部分可演变而诱发急性关节炎、痛风石、肾结石及尿酸肾病。3健康教育的内容3·1均衡饮食，减少高嘌呤饮食尿酸是嘌呤代谢的最终产物，果糖摄入过多可导致体内腺嘌呤核苷酸产生增多，进而促进尿酸的生成，故应少食含果糖多的食物，每日嘌呤的摄入量应50 mg。

In part 1, a practical one-step RP-HPLC method thatcan simultaneous determine hypoxanthine, xanthine, uric acid, allantoin and creatinine in blood and urine was established.

人类高尿酸血症多为肾脏排泄尿酸减少的类型，而现有的建模方法在升高血尿酸的同时，也使尿尿酸含量显著增高。

Hypoxanthine and a uricase inhibitor were combined into the model drug to work out the rat＇s animal model for hyperuricemia. A comparison was made between the effect of hypoxanthine and that of the model drug on the subject＇s serum uric acid levels. Also, such factors as the dose effect and time effect of the model-building drug were investigated.

采取合用次黄嘌呤和尿酸酶抑制剂为模型药物，制备一种尿酸生成增多型大鼠高尿酸血症动物模型，比较了单用次黄嘌呤及合用尿酸酶抑制剂对受试动物血清尿酸水平的影响，并对造模药物的量效、时效关系等因素进行了考察。

Objective To observe the fluctuation of uric acid in serum on mouse after replicating model by using hypoxanthine and uricase inhibitor. Make certain the most proper approach and solvent for using uricase inhibitor.

目的 本实验考察次黄嘌呤、尿酸酶抑制剂复制大鼠代谢性高尿酸血症模型，观察造模后受试动物血清尿酸的变化，以确定尿酸酶抑制剂造模的最佳造模途径和溶剂。

Objective To analyse the clinical application quality of four kinds of uricase reagents:dry simple reagent of Changzheng company;liquid double reagent of Shanghai Kehua;liquid double reagent of Shanhai Shennergy-Diasys;liquid double reagent of Beijin Leadman.

目的 了解不同厂家四尿酸酶试剂即长征公司尿酸干粉单试剂、上海科华公司尿酸液体双试剂、上海申能公司尿酸液体双试剂、北京利德曼公司液体尿酸双试剂的临床应用质量方法对不同厂家尿酸试剂的精密度、线性、回收试验、干扰试验的比较以及试剂稳定性的观察。

1hyperuricemia subjects have greater risk for high lipemia, high blood sugar,hypertension, artherosclerosis, obesity,and adomen-obesity. 2Beer was a risk factor, but hyperuricemia has not relation with education degree and smoking. 3To prevent and to therapia hyperuricemia need control weight,below blood pressure and lipemia., sufficient movement, blank diet, control drinking.

1高尿酸血症常伴发高血压病、动脉粥样硬化、高脂血症、高血糖、腹型肥胖。2啤酒是促进高尿酸血症发病的重要的危险因素，但文化程度、吸烟与血尿酸水平的相关性无统计学意义。3预防和治疗高尿酸血症必需控制体重、降低血压和血脂，适量运动，清淡饮食，控制饮酒。

Methods: Research on middle-aged and old person who hospitalized in our hospital from January, 2000 to October,2006, measure the blood uric acidwith zymology, the boundary is SUA which is bigger than 420mmol/l, Comparate and analysis the clinical material of hypeluricemia group, hypeluricemia merge coronary disease group and normal uric acid group.

以2000年1月至2006年10月在我院住院的中老年人为研究对象，采用酶学测定血尿酸，以SUA大于420mmol/l为界限，比较分析高尿酸血症组及高尿酸血症合并冠心病组与尿酸正常组的临床资料。

Abstract］ objective to observe the effects of indapamide and losartan alone and combined treatment on the elder patients with hypertension,hypokalemia,hyperglycemia,uric acid,lipid,ect.methods one hundered and fifty patients with hypertension were randomly divided into three groups,with each of 50 cases.the levels of blood pressure,hypokalemia,blood sugar,uric acid,lipide were examined before and after treatment.results after 8 weeks the systolic and diastolic blood pressure were significantly lower.antihypertensive treatment group is the best,the levels of hypokalemia is lower after treatment in the indapamide group,the levels of uric acid is also lower in the losartan group and antihypertensive group.conclusion losartan and indapamide combined treatment not only coordinate to decrease blood pressure but also reduce uric acid,reduce the effect of hypokalemia caused by indapamide.

目的 观察氯沙坦与吲哒帕胺单独应用或联合用药对原发性高血压患者血压、血钾、血糖、尿酸、血脂的影响。方法将符合诊断标准的150例老年高血压患者电脑随机分为3组，每组50例，进行用药前后自身对照试验，8周后检测各组血压、血钾、血糖、尿酸、血脂值。结果 3组治疗后收缩压和舒张压均较前明显降低，联合治疗组降压幅度最大，氯沙坦组和联合治疗组治疗后尿酸值较治疗前降低，吲哒帕胺组治疗后血钾值较治疗前降低。结论氯沙坦与吲哒帕胺联合应用不仅具有协同降压作用，而且能降低尿酸，减轻吲哒帕胺引起的低钾血症。

Methods The adsorbing effect of montmorillonite was observed in vitro and the effect of decreasing serum concentration of uric acid was studied on acute hyperuricemia model mice. The concentration of uric acid was measured by the reduction method of phosphotungstic acid.

用离体实验研究蒙脱石对尿酸的吸附作用；用小鼠高尿酸血症模型研究蒙脱石降低血尿酸的作用；用磷钨酸还原法测定尿酸含量。

This is because:① hypertension caused by macrovascular disease, microvascular disease, the body part can hypoxia, blood lactate levels, leading to uric acid by inhibiting renal tubular secretion, coupled with increased synthesis of uric acid in patients, renal clearance of uric acid will reduce the functionality;② some long-term use in patients with hypertension Thiazide diuretics, the result of hypovolemia, which was repeated absorption of uric acid, thus leading to hyperuricemia.

这是因为：①高血压引起的大血管病变、微血管病变，可使机体部分组织缺氧、血乳酸水平升高，导致肾小管分泌尿酸受到抑制，加之病人体内尿酸合成增加，肾脏清除尿酸的功能就会降低；②部分高血压患者在长期使用噻嗪类利尿剂后，造成血容量减少，致使尿酸被重复吸收，从而引起高尿酸血症。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。