尿的

We coupled the IgG of monoclonal antibody N34 specific to UK and the Fab of monoclonal antibody SZ-51 specific to the membrane protein GMP-140 of activated platelet. The bispecific antibody (N34 SZ-51) is able to bind UK and plasma-clot simutaneously. It enhanced plasma clot lysis 5 fold by HUK whereas it enhanced plasma clot lysis 38 times by LUK. UK in association with the bispecific antibody didn't decrease the concentration of fibrinogen in the assay supernatants.

利用抗体介导使纤溶酶原激活剂定向到血栓表面，可大大提高其纤溶作用，我们用双功能团试剂将抗尿激酶的单克隆抗体N34的IgG和抗活化血小板膜蛋白GMP-l40的单抗SZ-5l的Fab片段通过二硫键共价偶联，合成的双专一性抗体（N34-SZ-51）既具有血栓亲和性也具有尿激酶亲和性，从而增加了尿激酶对血栓的专一性，使高分子量尿激酶溶栓率提高了5倍，使低分子量尿激酶溶栓率提高了38倍之多，且不影响血浆中纤维蛋白原的含量。

Results The NIH-CPSI score was 21.7±8.8 in the group,64.05% of the CPS patients had pain of perineal region,hypogastrium,inguinal groove and lumbosacral area.46.41% of them had urination irritation.41.18% of them felt dissatisfied,unhappy,even terrified with the symptoms of chronic prostatitis.Conclusion Controlling pain of perineal region and hypogastrium is important in the treatment of CP.

结果 306例患者的NIH-CPSI评分8～39分，平均（21.7±8.8）分，64.05%的患者有会阴部、外生殖器、小腹、腹股沟、腰骶部不同程度的疼痛不适，46.41%患者存在不同程度的尿频、尿急、尿等待、尿后淋漓等排尿刺激症状，41.18%存在情绪紧张、焦虑、乏力、压抑、失眠等精神症状。62.42%患者因职业原因有长期憋尿或长时间保持蹲姿或坐姿。59.15%患者有喜食辛辣或刺激性食物的饮食习惯。

Results The NIH-CPSI score was 21.7±8.8 in the group,64.05% of the CPS patients had pain of perineal region,hypogastrium,inguinal groove and lumbosacral area.46.41% of them had urination irritation.41.18% of them felt dissatisfied,unhappy,even terrified with the symptoms of chronic prostatitis.

结果 306例患者的NIH-CPSI评分8～39分，平均（21.7±8.8）分，64.05%的患者有会阴部、外生殖器、小腹、腹股沟、腰骶部不同程度的疼痛不适，46.41%患者存在不同程度的尿频、尿急、尿等待、尿后淋漓等排尿刺激症状，41.18%存在情绪紧张、焦虑、乏力、压抑、失眠等精神症状。62.42%患者因职业原因有长期憋尿或长时间保持蹲姿或坐姿。59.15%患者有喜食辛辣或刺激性食物的饮食习惯。

After +Gx, rhesus were anatomized and obtain tissues by means of HE staining with microscope, and collect urine for routine examination. Result:1 By light microiscopy, these were observed that nephroid ball differently swelled, nephroid vesicle dwindled,and serosity and red blood cell exuded out intovesicle. Denaturalization, putrescence and desquamation were found nephroid canaliculus epithelium, there were red conglomeration and cell in nephroid canaliculus.

结果1光镜下，与对照组相比实验组可见肾小球有不同程度的肿胀，囊腔变小甚至消失，内有数量不等的红细胞和浆液渗出；肾小管上皮细胞变性、脱落，管腔内有红染的团块和脱落的细胞成分。2常规尿液检测结果发现尿比重增加，尿液中有不同程度的潜血，尿中出现蛋白质，尿液的PH 值较对照组降低，另外，尿液中葡萄糖的含量降低。

BPH is a common disease in old people, it often causes bladder outlet obstruction and destrusor instability. It is reported that the morbidity, rate of detrusor instability secondary to BPH is from 52% to 80%. There are many hypotheses concerning detrusor instability, The study of detrusor denervational hypersensitivity and changes of detrusor ultra-structure are intensively popular at present. But most of the research work were only limited in animals. In order to gain the insight into its mechanism, we Carried out a series of studies on detrusor instability secondary to BPH obstruction in men.

BPH是老年人常见疾病，常导致膀胱出口梗阻和逼尿肌不稳定，有报道BPH梗阻性逼尿肌不稳定的发生率为52-80％，引起逼尿肌不稳定原因很多，其中逼尿肌去神经超敏和超微结构的变化是目前研究的热点，但大多限于动物实验，鉴于此，我们对BPH梗阻性逼尿肌不稳定进行了初步的研究，拟探讨其发生机制。

Abstract］ objective to discuss the effect of two kinds of nursing methods of male urinary incontinence patients to urinary tract infection and patient's comfortable influence of degree.methods 80 masculine urine incontinence patients in our hospital with voluntary will were chose,and divided them into the observation group and the comparison group,with 40 examples each.the observation group used bt-ⅰ high level chamber pot,the comparison group used the catheter.compared with 2 groups after nursing of the 3rd,7th,10th,14th day-long urethral meatus bacilliculture,the severance urine bacilliculture result and the urine road junction partial symptom.results compared the results of urine road and severance urine bacilliculture,and the urine road junction partial symptom of two groups,the observation group masculine positive rate was obviously lower than the comparison group,the difference had statistics significance（p.05）.conclusion using bt-ⅰ chamber pot can effectively enhance the nursing effect of the masculine urine incontinence patients'perineum and periphery skin,enhance the patients' degree of comfort.

目的 探讨男性尿失禁患者两种护理方法对尿路感染及患者舒适度的影响。方法本着患者及家属自愿选择的原则将入住我院的男性尿失禁患者80名分为观察组和对照组各40例。观察组利用bt-ⅰ型高级透气接尿器，对照组采用留置导尿管，比较两组护理后第3、7、10、14天的尿道口的细菌培养结果及尿道口的局部症状。结果两组患者尿道口培养结果及尿道口局部不良症状比较，观察组阳性率明显低于对照组，差异有统计学意义（p＜0.05）。结论使用bt-ⅰ型接尿器可有效提高男性尿失禁患者会阴及周围皮肤的护理效果，提高患者的舒适度。

Result: Unstable bladder in 9 cases(45%), low compliance bladder in 5 cases (25%), obstruction in the bladder outlet in 11 cases (55%), dyssynergia in detrusor muscle and external urethral sphincter in 7 cases (35%), unstable bladder with obstruction in the bladder outlet in 6 cases, low compliance bladder with obstruction in the bladder outlet in 4 cases , unstable bladder with dyssynergia in detrusor muscle and external urethral sphincter in 2 cases .

结果：不稳定性膀胱9例（45%），低顺应性膀胱5例（25%），膀胱出口梗阻11例（55%），逼尿肌尿道括约肌协同失调7例（35%），其中不稳定膀胱合并膀胱出口梗阻6例，低顺应性膀胱合并膀胱出口梗阻4例，不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。结论：慢性前列腺炎患者的下尿路症状与不稳定性膀胱、低顺应性膀胱、膀胱出口梗阻及逼尿肌尿道外括约肌协同失调有关，了解这些相关因素对治疗有重要的指导意义。

Result: unstable bladder in 9 cases(45%), low compliance bladder in 5 cases (25%), obstruction in the bladder outlet in 11 cases (55%), dyssynergia in detrusor muscle and external urethral sphincter in 7 cases (35%), unstable bladder with obstruction in the bladder outlet in 6 cases, low compliance bladder with obstruction in the bladder outlet in 4 cases , unstable bladder with dyssynergia in detrusor muscle and external urethral sphincter in 2 cases .conclusion : the symptom of inferior urinary tract in patients with chronic prostatitis urodynamic was related to the unstable bladder, low compliance bladder , obstruction in the bladder outlet and dyssynergia in detrusor muscle and external urethral sphincter ,to know the correlation factors do significant benefit in guiding the clinical treatment.

结果：不稳定性膀胱9例（45%），低顺应性膀胱5例（25%），膀胱出口梗阻11例（55%），逼尿肌尿道括约肌协同失调7例（35%），其中不稳定膀胱合并膀胱出口梗阻6例，低顺应性膀胱合并膀胱出口梗阻4例，不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。结论：慢性前列腺炎患者的下尿路症状与不稳定性膀胱、低顺应性膀胱、膀胱出口梗阻及逼尿肌尿道外括约肌协同失调有关，了解这些相关因素对治疗有重要的指导意义。

Results in MUPP: We evaluated 43 patients with MUPP and manufactured some typical plots to diagnose some of the lower urinary tract disease, including BPH, functional bladder neck obstruction, detrusor-external sphincter dyssynergia, urethral stricture, the female stress incontinence, the female urethral meatal stenosis and so on.

一、MUPP检测结果：对43例有下尿路症状的病人进行了MUPP检测，制出了诊断下尿路疾病的典型图形，其中包括BPH、功能性膀胱颈部梗阻、逼尿肌-外括约肌协同失调、尿道狭窄、女性压力性尿失禁、以及女性尿道末端缩窄综合症等。

Increase of intravesical pressure would be the cause of vesico-ureteral reflux, hydronephrosis, and inpaired renal function.

此外尿失禁的问题也常令病人感到困扰，包括急迫性尿失禁、满溢性尿失禁、甚或是应力性尿失禁。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。