尿生成

The ability that the medicine's influence to the new vein's creation induced by tumour and the ability that the vein creating in solid tumor can be indirectly evaluated by scaling the medicine's influence to the new vein's creation of the chicken's allantoid membrane.

观察药物对鸡胚尿囊膜局部血管新生的影响可以用来间接地衡量药物影响肿瘤诱生新血管发生或实体瘤组织内血管生成的能力。

To observe method of chick embryo allantois membrane, judge neovascularisation, research the effect of angiogenesis by drugs by means of chick embryo allantois membrane model.

学会观察鸡胚尿囊膜血管的方法，判断新生血管形成，通过鸡胚尿囊膜模型探讨药物对血管生成作用的影响

Heart as an endocrine gland generating and secreting natriuretic peptides hormone.

心脏作为内分泌腺，生成和分泌钠尿肽激素。

Describe the structure of nephron, and the process in the formation of urine.

试述肾单位的组成及尿液生成的途径。

Methods The mercury in urine, which is the total amount of inorganic mercury in urine, including those produced from organic mercury after treated by potassium bromate and potassium bromide, is determined by atomic absorption spectrophotometer after reduction into mercury atom with sodium borohydride.

方法］尿样中汞（尿中无机汞和经溴酸钾－溴化钾处理尿中有机汞生成的无机汞之和）以硼氢化钠还原生成汞原子蒸气，用原子吸收光谱仪测定其汞的含量。

Objective To investigate the effect of shearing vagus for uropoiesis experiment in rabbits.

目的 研究迷走神经剪断对兔尿生成实验的影响。

This study consists 3 partsPart I: the research on the mechanism of affecting the growth of CAM vesselsBecause neoformative vessels is most related with bFGF and VEGF, this study designed bFGF, VEGF and the primer of its receptor, by the experiment of the generation of CAM vessels, draw the materials from CAM tissues consist account of vessels, by the experiment of RT-PCR, reserve the influence of HSYA on the expression of bFGF, VEGF, VEGF-R(flt-1) in CAM tissues.

本实验分为三部分：第一部分，HSYA影响鸡胚尿囊膜血管生成的机理研究由于新生血管与bFGF、VEGF及其受体的关系最为密切，本实验设计了bFGF、VEGF及其受体的引物，利用CAM血管生成实验，直接从富含血管的CAM组织上取材，通过RT-PCR实验，观察HSYA对CAM组织中上述三个基因表达的影响。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

These results suggest that shearing vagus effect on the uropoiesis experiment, so we infer that the mechanisms may be relate to the increased atrial natriuretic peptide.

说明迷走神经剪断对兔尿生成实验具有显著影响，推断其机制可能与心房钠尿肽分泌增多有关。

The thesis are divided into two parts. In the first part, we used 2,4,6-trichloro-1,3,5-triazine as the precursor to react with sodium which have been achieved by decomposing sodium hydrate at 623 K. At a low reaction temperature of 623 K, carbon nitride nanosphere、porous carbon nitride material and byproduct sodium chloride, would be produced.

本研究将分成两部份，第一部分是在低温下(623 K)将氢化钠粉末热裂解，生成表面积较大的熔融态金属钠，使气态的氰尿醯氯通入与熔融态金属钠在623 K反应，生成奈米氮化碳球、奈米孔洞性氮化碳材料及副产物氯化钠。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。