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尿嘧啶

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ABSTRACT OBJECTIVE :The aim of this experiment was to observe the effects of intraperitoneal,intraveinousand intragastric administration.

目的:研究5-氟尿嘧啶(5-Fu)腹腔、静脉和灌胃3种给药途径化疗的优劣。

Different doses of Chitosan were intraperitoneally injected into mice with sarcoma 180 and EAC cancer respectively for 10 days.

结果:硫酸壳聚糖高、低剂量组和氟尿嘧啶组的抑瘤率分别为38.67%、30.19%和43.27%,3组的生命延长率分别为65.38%、69.23%和54.93%。

Objective To investigate the clinical significance of large intestinal cancer5-FU treated with portal intubation chemotherapy.

目的 探讨大肠癌行5-氟尿嘧啶(5-FU)门静脉插管化疗的临床意义。

The most common adverse reactions included leucopenia, neutronpenia, gastrointestinal tract reactions and peripheral neuropathy, etc.

多西紫杉醇联合奥沙利铂、5-氟尿嘧啶及亚叶酸钙化疗方案治疗晚期胃癌的疗效显著,毒性反应患者能耐受,可能延长患者生存期。

In search of databases, the deduced products of sanP, sanQ, sanR, sanS, sanT and sanU show highest similarity to those of nikP2, nikQ, nikR, nikS, nikT and nikU of S. tendae respectively. In comparison with the proteins of identified function, it is indicated that sanP encodes a thioesterase, sanQ encodes a cytochrome P450, sanR encodes a uracil phosphoribosyltransferase, sanS encodes a carboxylase, sanT encodes a histidinol-phosphate aminotransferase and sanU encodes a mutase.

在蛋白数据库中比较结果表明,sanP、sanQ、sanR、sanS、sanT和sanU基因编码的蛋白分别和唐德链霉菌的尼可霉素生物合成基因nikP2、nikQ、nikR、nikS、nikT、nikU六个基因编码的蛋白同源性最高;根据和已知功能蛋白的比较,推测sanP基因编码的是硫酯酶,sanQ基因编码的是细胞色素P450,sanR基因编码的是尿嘧啶磷酸核糖转移酶,sanS基因编码的是羧化酶,sanT基因编码的是组氨醇磷酸氨基转移酶,sanU基因编码的是一种变位酶。

Uracil A nitrogenous base that is found in RNA but not in DNA.

尿嘧啶:存在于 RNA 而非 DNA 中的一种含氮碱基。

The method is raw material with pyrimidine of 5- fluorine make water, after reacting with chloric second acid below the intention that changes potassium in oxyhydrogen, with complex intermediate body 2- amino - 5- is replaced - 1, 3, 2 Zun reaction makes 4- Sai target content, evaluate its to fight tumor active.

方法以5-氟尿嘧啶为原料,在氢氧化钾的功能下和氯乙酸反应后,和合成的中间体2-氨基-5-取代-1,3,4-噻二唑反应制得目标物,并评价其抗肿瘤活性。

More prophase and prometaphase cells may be obtained by this technique.

在培养基中加入5-溴脱氧尿嘧啶核苷使细胞同步化6—8小时,可以得到较多的前期和前中期分裂细胞。

Objective To observe the effects of 5-fluorouracil(5-FU) on prognosis of septic shock in rats.

目的观察5氟尿嘧啶(5FU)对脓毒性休克大鼠预后的影响。

OBJECTIVE: To determine the content of 5-Fu in human serum.

目的:测定5-氟尿嘧啶在人血清中的浓度。

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