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尿嘧啶

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Objective This study was aimed at optimizing the preparation of 5-Fluorouracil and peanut agglutinin conjugates so as to obtain a conjugate with high activity and high drug ratio, and to choose a suitable dosage form in the light of its properties.

目的 优化5-氟尿嘧啶(5-Fu)-花生凝集素结合物的反应条件,以期制备得到既有生物活性又有较高药物结合率的结合物。

During TRANSCRIPTION, the thymine of the DNA template is substituted by a uracil in the RNA copy.

转录过程中 DNA 模板链的胸腺嘧啶对应 RNA 复制链上的尿嘧啶

The dose-effect of the implantation of N+ and Ar+ on thymine and uracil were studied in this paper. Simulative curves were given when the sputtering of the intact sample molecules and the decomposition of the sample were taken into account.

本文研究了低能N+和Ar+注入对胸腺嘧啶和尿嘧啶的剂量效应,并分别给出了在考虑离子对样品的溅射和损伤的情况下的拟合曲线。

A form of post-transcriptional modification to mRNA in eukaryotes in which cytosine is deaminated to form uracil.

一种形式的真核生物转录后修饰作用,修饰时将胞嘧啶脱氨基形成尿嘧啶

Using chemical treatment, the kit converts all unmethylated cytosine residues to uracil.

使用化学处理,该套件会将所有未甲基化的胞嘧啶残留尿嘧啶

Seven compounds have been isolated from hard coral Acropora pulchra. These compounds are:pentadecoic acid, heptadecyl ester;(2)n-cetanol;(3)batyl alcohol;(4) N- [ 1 --2-hydroxyl--3,7-heptad-ecadienal] -hexadecanamide;(5)1 -0-hexanoyl-glycerol ester;(6)thymine;(7)uracil. Their structures were determined by IR, MS, HNMR, 13CNMR analysis.

从北海佳丽鹿角珊瑚Acropora pulchra乙醇提取液的乙酸乙酯部分分离出七个化合物,经IR、MS、~1HNMR、~(13)CNMR等波谱方法鉴定,其结构分别为:(1)十五酸十七酯,(2)正十六碳醇,(3)鲨肝醇,(4)N-1-羟基甲基-2-羟基—-3,7-十七碳二烯基十六酸酰胺,(5)1-正十六酸甘油酯,(6)胸腺嘧啶,(7)尿嘧啶

Results Using different concentrations of 5fluorouracil to deal with A549 cells, with the increase in drug concentration and treatment time,cell survival rate decreased significantly;and low concentration of 5fluorouracil induced the cell spread and increased vacuolization within the cytoplasm, acridine orange staining showed an increase in acidic vesicles,high concentration made the cell round and cell apoptosis.

结果不同浓度的5氟尿嘧啶处理A549细胞,随着药物浓度的增加和处理时间的延长,细胞存活率明显下降;且低浓度使细胞呈铺展状态,细胞质内空泡增多,吖啶橙染色显示酸性膜泡增多,高浓度使细胞变圆,出现凋亡状态。

Objective: To synthesize 2-benzyloxy-5-fluoro-4-oxo-pyrimidine-3-butyric acid ethyl ester, the key intermediate in the synthesis of fluorouracil derivatives.

目的:合成氟尿嘧啶类衍生物合成中的关键中间体2-苄氧基-5-氟-4-嘧啶酮-3-丁酸乙酯。

Uridine is a white, odorless powder, C9H12N2O6, which is the nucleoside of uracil, important in carbohydrate metabolism, and used in biochemical experiments.

尿苷,白色无味粉末,c9h12n2o6,是尿嘧啶中的核苷,在糖类新陈代谢作用中很重要,用于生化实验中。

In DNA the corresponding sugar is the closely related deoxyribose. A ribose molecule combined with adenine, guanine, cytosine, or uracil forms a nucleoside; adding a phosphate group forms a nucleotide.

去氧核糖核酸中相应的糖类和去氧核糖密切相关核糖分子和腺嘌呤、鸟嘌呤、胞嘧啶或尿嘧啶形成核;再加上磷酸盐和磷酸酯便成为核。

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