尿嘧啶

The achievements of this paper are as follows:(1) A series of cantharidin derivatives, saccharide-cantharidin derivatives compounds, saccharide-5-fluorouracil derivatives compounds and 5-fluorouracil derivatives organotin complexes have been firstly synthesized.

本论文的创新点在于：首次合成了一系列斑蝥素衍生物，斑蝥素衍生物-糖化合物，5-氟尿嘧啶衍生物-糖化合物和5-氟尿嘧啶衍生物-有机锡配合物。

Technologies for determining methylation patterns in cancer cells, Methyl Light and COBRA, both of which were based on the deamination of methylated cytosines—which converts these cytosines to uracil residues—and identification of the converted sequence by analytical methods.

在上世纪80年代期间，研究的主要方法是PCR和克隆，两者都不涉及甲基化内容，因此很快就被弃用了。90年代，Laird开发了两类技术去检测肿瘤细胞中的甲基化模式，MethylLight和COBRA，两者都是以甲基化胞嘧啶的脱氨作用（将胞嘧啶转化为尿嘧啶残基）以及通过分析方法鉴定修改的序列为基础。

The most abundant bases are cytosine, thiamine, and uracil and adenine and guanine.

最丰富的碱基是胞嘧啶，胸腺嘧啶，尿嘧啶，腺嘌呤和鸟嘌呤。

Two modified beacons containing of uracil and hypoxanthine have been used to validate the assay on purified proteins with success. However, while applying the assay to cell extracts, the results were interfered by non-specific nuclease activities.

我们分别设计其中含有尿嘧啶以及inosine的分子信号，以测定尿嘧啶-核酸醣解酶（uracil-DNA glycosylase）以及次黄嘌呤-核酸醣解酶（hypoxanthine-DNA glycosylase）的活性。

The basic group has five kinds, respectively be adenine, guanine, cytosine, thymine and uracil.

碱基有五种，分别为腺嘌呤、鸟嘌呤、胞嘧啶、胸腺嘧啶和尿嘧啶。

"One of the purines or pyrimidines (cystosine, thymine, and uracil ) that occurs attached to the sugar component of DNa or RNa."

嘌呤或嘧啶(胸嘧啶、胸腺嘧啶和尿嘧啶)的一种，附着在脱氧核糖核酸或核糖核酸的糖分子上。

The codA gene encodes cytosine deaminase, which can deaminate nontoxic compound 5-fluorocytosine (5-FC) to the highly cytotoxic compound 5-fluorouracil (5-FU). 5-FU can influence the cells survival through interference with the synthesis metabolism of the RNA and DNA.

codA基因在细菌体内编码胞嘧啶脱氨酶，CD能把对细胞无毒的5-氟胞嘧啶(5-FC)脱氨成为有毒的5-氟尿嘧啶(5-FU)。5-FU通过干扰RNA和DNA的合成代谢从而影响细胞的生存。

Bisulfite modification: A total of 1μg of genomic DNA, obtained from culture cells or tissues, was modified by sodium bisulfite to convert unmethylated cytosines to uracils.

2亚硫酸氢钠修饰取1μg上述DNA经亚硫酸氢钠处理，将非甲基化的胞嘧啶转变为尿嘧啶，而甲基化的胞嘧啶保持不变。

Nucleosides are compounds composed of a purine or pyrimidine base (usually adenine, cytosine, guanine, thymine, uracil) linked to either a ribose or a deoxyribose sugar.

核苷是由嘌呤基，嘧啶基(通常是腺嘌呤，胞嘧啶，鸟嘌呤，胸腺嘧啶，尿嘧啶)与核糖或脱氧核糖相连而组成的化合物。

One of the purines or pyrimidines that occurs attached to the sugar component of DNA or RNA.

碱基嘌呤或嘧啶（胸嘧啶、胸腺嘧啶和尿嘧啶）的一种，附着在脱氧核糖核酸或核糖核酸的糖分子上

Shop assistant: Please check at the door.

店员：请您到门口柜台交费。

In the end, transportation of PAHs in the environmental matrix was preliminarily investigated and discussed according to PAHs data of soils and sediments from a certain region in Shanghai. The result indicated that there are two or more pathways on PAHs transportation in the environmental matrix.

最后，对上海特定地区内PAHs在环境介质中的迁移径途进行了分析讨论，结果表明上海市土壤和沉积物等环境介质中PAHs的迁移存在多种途径。