尿嘧啶

Result: Six compounds were isolated and identified as vanillic acid, formononetin, isoliquiritigenin, liquiritigenin, kumatakenin B and uracil.

结果 ：从四逆汤水煎剂的乙酸乙酯萃取部分分得 6个化合物，分别鉴定为香草酸(1)，芒柄花素(2 )，异甘草素(3)，甘草素(4)，华良姜素B(5 )和尿嘧啶(6 )。

Objective To observe the clinical effect in treating metastatic liver cancer in artery interventional and vein chemotherapy with oxaliplatin, 5-fluorouracil deoxyribonucleoside and citrovorum factor, mitomycin +lipiodol.Methods 38 non-operable cases of metastatic liver cancer were given transfemoral artery chemoembolization, catheterical head was placed into tumors feeding artery(common hepatic artery, left of right hepatic artery, hepatic segmental artery), veinous chemotherapy in the next day.

目的 观察奥沙利铂(Oxaliplatin， L-OHP)联合氟尿嘧啶脱氧核苷、亚叶酸钙、丝裂霉素+超液化碘油动脉介入+静脉化疗双通路对转移性肝癌的临床疗效方法不能手术的转移性肝癌38例，经皮股动脉穿刺插管至腹腔动脉，并超选至肿瘤的供血供氧血管后灌注化疗药并栓塞，于次日再给予静脉化疗。

They were two new compounds, [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7],[2-N-(1-methoxycarbonylethyl)guanosine, 10], and eight known compounds,(p-hydroxybenzoic acid, 1),(methyl succinate, 2),(russulaceramide, 3),(phenylalanine, 4),(guanine, 5),(β-carboline, 6),(uridine, 8), and (adenosine, 9). All the compounds were isolated from Amanita exitialis for the first time.

分别为：对羟基苯甲酸(p-hydroxybenzoic acid，1)、丁二酸二甲酯(methyl succinate，2)、神经酰胺(russulaceramide，3)、苯丙氨酸（phenylalanine，4）、鸟嘌呤核苷(guanine，5)、β-咔啉(β-carboline，6)、环（脯氨酸-缬氨酸-苯丙氨酸-苯丙氨酸-脯氨酸-缬氨酸-苯丙氨酸-丝氨酸-亮氨酸） [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu)，7]、尿嘧啶核苷(uridine，8)、腺嘌呤核苷(adenosine，9)、2-N-(1-甲氧羰基乙基)鸟苷[2-N-(1-Methoxycarbonylethyl)guanosine， 10]。10个化合物均为首次从致命鹅膏中分离得到，其中化合物7和10为新化合物。

A series of novel polyethylene glycol derivates was synthesized by esterification of chloroacetic acid with polyethylene glycol. Because of the good reactive activity of α-chlorin in the esters it can react with 5-fluorouracil, thus the conjugate can be obtained .

采用氯乙酸与不同分子量的聚乙二醇进行酯化反应得到氯乙酸聚乙二醇酯，由于酯中的α-氯具有良好的反应活性，将它再与抗癌药物5-氟尿嘧啶结合制备了不同分子量的高分子前药。

Topical fluorouracil for actinic keratoses and photoaging: a clinical and molecular analysis.

局部氟尿嘧啶治疗光化性角化病和光老化：一项临床和分子分析 _文摘译讯_医脉通，www.medlive.cn

METHODS: In mobilization group (M, n=10), granulocyte-colony stimulating factor (30 μg·kg-1·d-1) was injected subcutaneously 3 hours after MI and every 24 hours for 5 days. On the 5th day, the BMCs from 10 mL peripheral blood were labeled with bromodeoxyuridine for 24-48 hours, then reinjected intravenously. In transplantation group (T, n=10), BMCs transplantation was performed 5-7 days after MI.

将30只新西兰兔采用结扎前降支的方法复制心肌梗死模型，随机分为动员组、移植组和对照组，动员组（n=10）心梗后3 h开始皮下注射粒细胞集落刺激因子30 μg·kg-1·d-1，连续使用5 d，第5 d抽取静脉血约10 mL，分离单个核细胞用5-溴脱氧尿嘧啶核苷标记后，经静脉注入动物体内。

The study p roves that the formula of docetaxel combined with oxaliplaitin and fluorouracil is effective and its toxicity tolerable in treating advanced gastric cancer.

多西紫杉醇联合奥沙利铂和氟尿嘧啶方案治疗晚期胃癌的疗效较好，毒副反应可以耐受。

To observe the effect of 5-flurouracil (5-FU) with different doses and administration time on cell cycle uncoupling of Jurkat and EL-4 cell lines.

目的：研究5-氟尿嘧啶（5-FU）不同剂量和给药后不同时间Jurkat和EL-4细胞周期解偶联的变化规律。

An unusual substitution of 5-fluorouracils by the reaction of lithium salts of 1,3-dialkyl-5-fluorouracil with benzyl bromide is described.

1，3-二烷基-5-氟尿嘧啶的锂盐与苄基溴进行苄基化反应时产生了异常的反应结果。

In this thesis, shikonin, cryptotanshinone and 5-fluorouracil (5-FU) were selected as the objects for several aspect studies: In Chaper 2, the electrochemical behavior of shikonin was investigated by cyclic voltammetry, linear sweep voltammetry, chronocoulometry and bulk electrolysis with coulometry on a glassy carbon electrode. Triple strand DNA modified electrode was preparated and used to investigate the interaction of shikonin with DNA. It was found that it is hydroquinone of shikonin to embed in DNA and interacted with guanine and adenine of DNA.

本论文以紫草素、隐丹参酮和5-氟尿嘧啶三种抗癌药物为研究对象，做了以下几个方面的工作：在论文的第二章，我们研究了紫草素的电化学基本性质，初步探讨了三链DNA 修饰电极的制备，并利用该修饰电极研究紫草素与DNA 的相互作用，得出主要是紫草素的氢醌与DNA 的G、A 碱基间发生嵌插作用的结论。

Shop assistant: Please check at the door.

店员：请您到门口柜台交费。

In the end, transportation of PAHs in the environmental matrix was preliminarily investigated and discussed according to PAHs data of soils and sediments from a certain region in Shanghai. The result indicated that there are two or more pathways on PAHs transportation in the environmental matrix.

最后，对上海特定地区内PAHs在环境介质中的迁移径途进行了分析讨论，结果表明上海市土壤和沉积物等环境介质中PAHs的迁移存在多种途径。