尿嘧啶

Here, we introduce a novel method for monitoring uracil removal in real-time.

UDG酶是一种能特异消除损伤碱基尿嘧啶的蛋白，在防止基因突变，调节免疫功能等方面具有重要意义。

Study on the Synthesis of Uracil Derivatives Ⅱ.Study on the Synthesis of 1, 4-Dihydro-s-Tetrazine Derivatives and Their Antitumor Activity

论文标题：Ⅰ。药物中间体尿嘧啶衍生物合成研究Ⅱ。1，4-二氢-s-四嗪衍生物的合成及抗肿瘤活性研究

The main point is to illustrate the effect of Uracil, ITS, and ATP on bovine oocytes'maturation.

旨在探讨成熟液中添加尿嘧啶和三价因子等试剂对牛卵母细胞成熟的影响。

Fluorouracil is a kind of popular antimetabolic drug used in clinic.It has the similar structure with uracil which is necessary to the cancer cell.

5-氟尿嘧啶(5-Fu)是一种在临床上已为人们熟知的一类抗瘤谱广、有效率高的抗代谢药物。

Structure resembles uracil with an attached bromine group.

带有溴基团的结构与尿嘧啶相似。

Dietary orotate had more potent growth-stimulatory effects than uracil in this animal model.

在这一动物模型中，乳清酸比尿嘧啶更能有效地刺激生长。

It contents with uracil in the same enzyme system,blocks the metabolic link,impeds the synthesis of DNA,and then prohibits the propagation of the cancer cells.

它的结构与肿瘤细胞所必需的代谢结构尿嘧啶相类似，在同一系统酶中互相竞争，阻断代谢环节，阻碍DNA的合成，从而抑制肿瘤细胞的增殖。

Objective: To evaluate the inhibitory effect of intraperitoneal sustained-release chemotherapy with 5-FU on the growth of H22 ascitic tumor in mice.

目的：观察5-氟尿嘧啶(5-FU)腹腔内缓释化疗对H22腹水瘤小鼠的抑瘤作用。

Result: Eight compounds were isolated and they were identified as β-sitosterol (1), succinic acid (2), luteolin-7-O-β-D-glucoside (3), uracil (4), apigenin (5), chrysoeriol (6), chrysoeriol-7-O-β-D-glucoside (7), and apigenin-7-O-β-D-glucoside (8). Conclusion: Compound 4-8 were isolated from L.

结果：从藏药短管兔耳草醋酸乙酯提取物中分离得到8个化合物，经鉴定分别为β-谷甾醇（1），琥珀酸（2），木樨草素-7-O-β-D-葡萄糖苷（3），尿嘧啶（4），芹菜素（5），柯伊利素（6），柯伊利素-7-O-β-D-葡萄糖苷（7）和芹菜素-7-O-β-D-葡萄糖苷（8）。

Objective to evaluate the functional recovery of acute spinal cord injuried rats treated with exogenous wnt-3a signal protein administration and to explore its mechanism.methods moderate spinal cord contusion injury was made in 40 adult sprague dawley rats at t10.twenty rats served as contusion controls(group 1).twenty rats were treated with wnt-3a for three days after injury (group 2).the functional recovery of the rats was observed through basso,beattie,bresnahan open field locomotor score.rats were killed at 14 or 28 days after injury,then spinal cords were removed for histopathological examinations,and the expression of the bromodeoxyuridine plus neural cell markers was stained with immunohistochemical method.results rats of two groups receiving a contusive injury recovered substantial function within 1 week.by 28 days,rats in groups 2 scored 7.0 points better on the bbb scores than rats in group 1 group 2=16.94,after 28 days vs.

目的 研究外源性wnt-3a信号蛋白对脊髓损伤的修复作用，并探讨其作用机制。方法取40只成年雌性sd大鼠在t10节段制备适度脊髓挫伤模型。随机从中取20只为损伤对照组(group 1)，另外20只为损伤治疗组(group 2)。脊髓损伤3天后用wnt-3a蛋白治疗。这些大鼠的功能恢复通过basso、beattie、bresnahan开放视野运动评分来观察。这些大鼠分批在损伤后14天或28天被处死，取出损伤节段脊髓用来组织病理学检查，同时用5-溴脱氧尿嘧啶核苷和神经细胞标记物进行免疫组化染色。结果两组大鼠在伤后一周运动功能有明显的恢复。不过，到损伤后28天，我们观察发现，损伤治疗组中的大鼠bbb评分比损伤对照组中的评分高出7.0分左右(group 2∶16.94±1.18，group 1∶9.89±1.29；p.05)，光镜和电镜检查发现wnt-3a蛋白对髓鞘形成和轴突再生有一定的修复效果。

Shop assistant: Please check at the door.

店员：请您到门口柜台交费。

In the end, transportation of PAHs in the environmental matrix was preliminarily investigated and discussed according to PAHs data of soils and sediments from a certain region in Shanghai. The result indicated that there are two or more pathways on PAHs transportation in the environmental matrix.

最后，对上海特定地区内PAHs在环境介质中的迁移径途进行了分析讨论，结果表明上海市土壤和沉积物等环境介质中PAHs的迁移存在多种途径。