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Objective To detect antigenicity of collagen of cysticarcus cellulosae.

目的检测猪囊尾蚴胶原蛋白的抗原性。

METHODS: Nine rabbits were infected with monosexual cercariae, 7 rabbits were infected with bisexual cercariae as controls.

用单雄性和单雌性尾蚴分别感染9只家兔,以复性尾蚴感染7只家兔作对照;感染后定期采血。

Methodsthe Ginger oil were loaded on the slides, and the time of killing the Schistosoma Cercariae was recorded.

取生姜油100μl于载玻片上,观察生姜油杀灭血吸虫尾蚴的时间;并用已杀灭的血吸虫尾蚴感染小鼠,经灌注法加撕碎法收集虫体,计算感染率。

Many studies of immune mechanisms in radiation-attenuated cercariae immuned mice models show that the high protective immunity is mediated by CD4+T cell.

在辐照致弱尾蚴免疫小鼠等动物模型中的免疫机制研究表明,辐照致弱尾蚴诱导所产生的高保护力主要是由CD4+T细胞介导的细胞免疫。

Furthermore, the average number of S .japonicum cercariae shed from superinfected snails were significantly less than that of single S.japonicum infected control.

对各试验组及对照组钉螺逸出尾蚴试验发现,试验组钉螺血吸虫尾蚴逸出量均显著低于对照组的逸出量。

After applied in vivo,NX1resultsin cell apoptosis of cysticerci first and then necrosis appears under theinvolvement of some factors from hosts.

6说明NX1体内作用后,首先引起猪囊尾蚴细胞发生凋亡,而后在宿主因素参与下导致猪囊尾蚴细胞发生坏死。

In this test, metabolites and enzyme activities involved in energy metabolism in Cysticercus cellulosae were determined systematicly in vivo and in vitro and under action of drugs.The principles of variation of energy metabolism in Cysticercus cellulosae and mechanism of action of the benzimidazol carbamate drugs were illustrated so as to select an effective drug against immature and mature cysticerci and to provide a theoretical and experimental chemotherapy.

本研究首次系统地测定了体内发育过程中、体外培养条件下及抗囊药物作用下猪囊尾蚴能量代谢的有关物质含量和酶活性的变化,阐明了猪囊尾蚴的能量代谢变化规律和苯并咪唑氨基甲酸酯类药物作用机理,为筛选有效的抗囊药物以及为药物治疗提供了重要的实验和理论依据。

No cysticercus cellulosae was found in various organs of pigs 10 days after infection; but asmall amount of immature form could be detected in liver 15-30 days after infection, the number of cysticerci parasitized in liver gradually increased.

感染40~70d时在肝脏寄生的囊尾蚴数量增多,同时开始在前肢和后肢的肌肉、胸肌、颈肌、脑组织、肾脏、肺脏内逐步见到未成熟的囊尾蚴

The results showed that a number of cysticerci cellulosae in the pigs were alive in dose of 20mg/kg,and all the cysticerci cellulosae in the pigs died and were absorbed,the musclar tissue was cured ,and a few small nodes of calcification were found in the bra...

结果表明,治疗剂量为20mg/kg组病猪体内囊尾蚴多数仍具有活力;治疗剂量为40、80、160mg/kg组病猪肌肉组织内的囊尾蚴全部死亡并被吸收,肌肉组织结构正常,脑组织内残留少量小钙化灶。

The histological observation showed that the larvae of S .japonicum in superinfected snails were sluggish in development, irregular, shrunken, deformed, relatively small in number as compared with the control. The sporocysts contained few germ balls or immature cercariae and most of the digestive glands of superinfected snails were atrophiej.

组织学观察发现各双重感染组钉螺消化腺萎缩,消化腺盲囊间隙只有少量血吸虫子胞蚴,血吸虫子胞蚴皱缩、变形及不规则,且子胞蚴中只含稀疏的尾蚴胚球,有的子胞蚴中已无胚球;而单独感染血吸虫的对照组中血吸虫均发育到成熟的子胞蚴或尾蚴

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