尾蚴

ObjectiveTo evaluate the efficacy of the Ginger oil killing the Schistosoma japonicum Cercariae.

目的探讨生姜油杀灭日本血吸虫尾蚴的效果。

Objective To explore antigens possessing common immunogenicity with Schistosoma japonicum cercariae antigens, and to find out new candidate antigens for schistosomiasis diagnosis and vaccine.

目的 筛选与日本血吸虫尾蚴抗原有共同免疫原性的日本血吸虫成虫抗原分子，为血吸虫病诊断和疫苗研究提供新的候选分子。

Results Optimal result in enriching schistosoma cercariae was obtained by using the desinged device with the filtering net of 400 hole at diving pump power of 40 watts for a duration of 5 hours.

结果 在潜水泵功率40瓦、富集5h和滤网目数为400目时，富集装置对疫水中尾蚴的富集效果最好。

Objective To explore the feasibility of establishing animal model of schistosomiasis through subcutaneous injection of IMDM liquid and intramuscular injection of IMDM liquid both of which contained the cercariae.

目的探讨尾蚴经IMDM悬液皮下注射和肌肉注射感染动物建立动物模型的可行性。

Then 30 cercariae of Schistosoma japonicum were given per mouse by abdominal skin inoculation.

第3次免疫后5d经腹部皮肤攻击感染大陆株日本血吸虫尾蚴30条／鼠。

Methods Forty mice were randomly divided into 4 groups: one normal control group,mice in the other three groups were all infected each with 25 cercariae, the infected control group was fed for 10 weeks after infection, and 2 weeks after infection, the high dose PTX group was given PTX 360 mg/ for 8 weeks and the low dose PTX group was given PTX 180 mg/also for 8 weeks.

将40只小鼠随机分为4组，其中3组每只小鼠人工感染日本血吸虫尾蚴25条，1组感染后继续喂养10周，不作治疗，作为感染对照组；2组分别于感染后2周用PTX 360 mg/和180 mg/灌胃治疗8周；另1组不感染、也不接受药物治疗，与上述3组同步喂养10周，作为正常对照组。10周后将上述4组小鼠分别剖杀取肝组织，光镜观察肝组织病变；用免疫组化染色方法检测小鼠肝组织中Bcl-2、Bax的水平。

A diameter 80 μm schistosoma entice cercariae molecularly imprinted polymers was synthesized by molecularly imprinted technology.

采用分子印迹技术，直接合成出粒径在80μm左右的血吸虫诱尾蚴剂分子印迹聚合物。

Methods Balb/c mice were immunized subcutaneously three times （0,2,4 weeks） with rSj 32 emulsified with adjuvant. Each mouse was infected with （40±1） curacies of Sj （6 weeks）. After 42 days of infection, the mice were killed and the worm number was counted.

用rSj 32×103加佐剂免疫小鼠3次，分别在0、2、4周进行，第6周每鼠经腹部感染（40±1）条日本血吸虫尾蚴，感染后42 d剖杀，计算减虫率。

Results The expression of TNF-α mRNA in egg granulomas in t...

结果 疫苗免疫，尾蚴攻击后小鼠肝虫卵肉芽肿细胞内TNF－α mRNA表达显著加强。

Rabbits were treated 18 weeks after infection with praziquantel 100mg/kg/day for 2 days. All cured rabbits showed an excellent recovery 20-36 weeks after treatment with favorable pathological changes: i.e.,(1)disappearance of vasodilatation, with decrease of hepatic arterioles and increase of portal branches;(2) disappearance of black-brown color, nodular appearance a...

感染尾蚴后18周，用吡喹酮100mg/kg/日进行两天治疗，所有治愈家兔肝脏血管模型、病理形态及组织学的异常变化均在停药后20～36周得到很好恢复，提示吡喹酮是一个治愈血吸虫病肝硬化较为理想的药物。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。